Browsing Institutt for klinisk medisin by Author "Aabakken, Lars"

Now showing items 1-20 of 33

  • A framework with a fully convolutional neural network for semi-automatic colon polyp annotation 
    Qadir, Hemin Ali; Solhusvik, Johannes; Bergsland, Jacob; Aabakken, Lars; Balasingham, Ilangko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Deep learning has delivered promising results for automatic polyp detection and segmentation. However, deep learning is known for being data-hungry, and its performance is correlated with the amount of available training ...
  • A low FODMAP diet reduces symptoms in treated celiac patients with ongoing symptoms–A randomized controlled trial 
    van Megen, Frida; Skodje, Gry Irene; Lergenmuller, Simon; Zühlke, Stephanie; Aabakken, Lars; Veierød, Marit Bragelien; Henriksen, Christine; Lundin, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background & Aims A gluten-free diet usually leads to mucosal remission in celiac disease, but persistent symptoms are common. A low fermentable oligo-, di-, monosaccharides and polyols (FODMAP) diet is an established ...
  • A novel intragastric balloon for treatment of obesity and type 2 diabetes. A two-center pilot trial 
    Tønnesen, Christer Julseth; Hjelmesæth, Jøran Sture; Hofsø, Dag; Tonstad, Serena; Hertel, Jens Kristoffer; Heggen, Eli; Johnson, Line Kristin; Mathisen, Tor Erik; Kalager, Mette; Wieszczy, Paulina; Medhus, Asle Wilhelm; Løberg, Magnus; Aabakken, Lars; Bretthauer, Michael (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background and aims: Obesity with type-2 diabetes is a global challenge. Lifestyle interventions have limited effect for most patients. Bariatric surgery is highly effective, but resource-demanding, invasive and associated ...
  • A pilot study of implementation of endoscopic sleeve gastroplasty (ESG) in Norway 
    Tønnesen, Christer Julseth; Hjelmesæth, Jøran Sture; Aabakken, Lars; Lund, Randi Størdal; Johnson, Line Kristin; Hertel, Jens Kristoffer; Kalager, Mette; Løberg, Magnus; Bretthauer, Michael (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background and aim Bariatric surgery is the most effective treatment for obesity but is invasive and associated with serious complications. Endoscopic sleeve gastroplasty (ESG) is a less invasive weight loss procedure ...
  • Assessment of the effect of an Interactive Dynamic Referral Interface (IDRI) on the quality of referral letters from general practitioners to gastroenterologists: a randomised cross-over vignette trial. 
    Eskeland, Sigrun Losada; Brunborg, Cathrine; Rueegg, Corina Silvia; Aabakken, Lars; de Lange, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Objectives: We evaluated whether interactive, electronic, dynamic, diagnose-specific checklists improve the quality of referral letters in gastroenterology and assessed the general practitioners’ (GPs’) acceptance of the ...
  • Automatic colon polyp detection using region based deep CNN and post learning approaches 
    Shin, Younghak; Qadir, Hemin Ali Qadir; Aabakken, Lars; Bergsland, Jacob; Balasingham, Ilangko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Automatic image detection of colonic polyps is still an unsolved problem due to the large variation of polyps in terms of shape, texture, size, and color, and the existence of various polyp-like mimics during colonoscopy. ...
  • CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile 
    Bartolomé Casado, Raquel; Landsverk, Ole J. B.; Chauhan, Sudhir Kumar; Sætre, Frank Ove; Hagen, Kjersti Thorvaldsen; Yaqub, Sheraz; Øyen, Ole; Horneland, Rune; Aandahl, Einar Martin; Aabakken, Lars; Bækkevold, Espen Sønderaal; Jahnsen, Frode Lars (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Studies in mice and humans have shown that CD8+ T cell immunosurveillance in non-lymphoid tissues is dominated by resident populations. Whether CD4+ T cells use the same strategies to survey peripheral tissues is less ...
  • Clinical variables as indicative factors for endoscopy in adolescents with esophageal atresia 
    Mikkelsen, Audun; Møinichen, Unn Inger; Reims, Henrik Mikael; Grzyb, Krzysztof; Aabakken, Lars; Mørkrid, Lars; IJsselstijn, Hanneke; Emblem, Ragnhild (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Introduction Gastro-esophageal reflux disease (GERD) occurs frequently in patients operated for esophageal atresia (EA). Longstanding esophagitis may lead to dysphagia, strictures, columnar metaplasia, and dysplasia with ...
  • Colorectal polypectomy and endoscopic mucosal resection: European Society of Gastrointestinal Endoscopy Cascade Guideline 
    Karstensen, John Gásdal; Ebigbo, Alanna; Desalegn, Hailemichael; Afihene, Mary; Anigbo, Gideon; Antonelli, Giulio; Bhat, Purnima; Duduyemi, Babatunde; Guy, Claire; Ijoma, Uchenna; Ponchon, Thierry; Rahmi, Gabriel; Aabakken, Lars; Hassan, Cesare (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Colorectal cancer (CRC) is a major contributor to morbidity and cancer death globally with an increasing incidence also in low- and middle-income countries [1] [2]. However, CRC is preventable if precursor lesions are ...
  • Comparison between Enteroscopy-, Laparoscopy- and Endoscopic Ultrasound-Assisted Endoscopic Retrograde Cholangio-Pancreatography in Patients with Surgically Altered Anatomy: A Systematic Review and Meta-Analysis 
    Gkolfakis, Paraskevas; Papaefthymiou, Apostolis; Facciorusso, Antonio; Tziatzios, Georgios; Ramai, Daryl; Dritsas, Spyridon; Florou, Theodosia; Papanikolaou, Ioannis S.; Hassan, Cesare; Repici, Alessandro; Triantafyllou, Konstantinos; Aabakken, Lars; Devière, Jacques; Beyna, Torsten; Arvanitakis, Marianna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background and Aims: Endoscopic retrograde cholangiopancreatography (ERCP), in surgically altered anatomy (SAA), can be challenging and the optimal technique selection remains debatable. Most common foregut interventions ...
  • Defining Primary Sclerosing Cholangitis: Results From an International Primary Sclerosing Cholangitis Study Group Consensus Process 
    Ponsioen, Cyriel Y.; Assis, David N.; Boberg, Kirsten Muri; Bowlus, Christopher; Deneau, Mark; Thorburn, Douglas; Aabakken, Lars; Färkkilä, Martti; Petersen, Bret; Rupp, Christian; Hübscher, Stefan G. (Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
  • Determination of lower cut-off levels of adalimumab associated with biochemical remission in Crohn's disease 
    Carlsen, Arne; Omdal, Roald; Karlsen, Lars Normann; Kvaløy, Jan Terje; Aabakken, Lars; Steinsbø, Øyvind; Bolstad, Nils; Warren, David; Lundin, Knut Erik Aslaksen; Grimstad, Tore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background and Aim Adalimumab is administered and dosed using a standardized treatment regimen. Although therapeutic drug monitoring (TDM) may help optimize treatment efficacy, the lower cut‐off concentration of adalimumab ...
  • Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile 
    Vedeld, Hege Marie; Grimsrud, Marit Mæhle; Andresen, Kim; Pharo, Heidi Dietrichson; von Seth, Erik; Karlsen, Tom Hemming; Honne, Hilde; Paulsen, Vemund; Färkkilä, Martti A.; Bergquist, Annika; Jeanmougin, Marine; Aabakken, Lars; Boberg, Kirsten Muri; Folseraas, Trine; Lind, Guro Elisabeth (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background and Aims Primary sclerosing cholangitis (PSC) is associated with increased risk of cholangiocarcinoma (CCA). Early and accurate CCA detection represents an unmet clinical need as the majority of patients with ...
  • Effects of faecal microbiota transplantation on the small intestinal mucosa in systemic sclerosis 
    Strahm, Noemi; Didriksen, Henriette; Fretheim, Håvard Halland; Molberg, Øyvind; Midtvedt, Øyvind; Farstad, Inger Nina; Midtvedt, Tore; Lundin, Knut; Aabakken, Lars; Błyszczuk, Przemysław; Distler, Oliver; Kania, Gabriela; Hoffmann-Vold, Anna-Maria (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Objectives In SSc, gastrointestinal tract (GIT) involvement is a major concern, with no disease-modifying and limited symptomatic therapies available. Faecal microbiota transplantation ...
  • Electronic checklists improve referral letters in gastroenterology: a randomized vignette survey 
    Eskeland, Sigrun Losada; Rueegg, Corina Silvia; Brunborg, Cathrine; Aabakken, Lars; de Lange, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Objective: Investigate whether gastroenterologists rate the quality of referral letters higher if electronic dynamic checklist items are added to a standard free-text referral letter. Assess how this affects the ...
  • Endoscopic retrograde cholangiopancreatography in infants and children 
    Åvitsland, Tone Lise; Aabakken, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Background and study aims Previous reports have suggested that endoscopic retrograde cholangiopancreatography (ERCP) in pediatric patients are safe. However, the total number of cases presented in the ...
  • Endoscopy assistants influence the quality of colonoscopy 
    Holme, Øyvind; Pedersen, Ina Borgenheim; Medhus, Asle Wilhelm; Aabakken, Lars; Glomsaker, Tom Birger; Kvamme, Jan-Magnus; Løberg, Magnus; Bretthauer, Michael; Seip, Birgitte Karen Berggreen; Kjellevold, Øystein; Jørgensen, Anita; Furholm, Siv; Hoff, Geir; de Lange, Thomas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Background: Colonoscopy performance varies between endoscopists, but little is known about the impact of endoscopy assistants on key performance indicators. We used a large prospective colonoscopy quality database to perform ...
  • ERCP for the initial management of malignant biliary obstruction–real world data on 596 procedures 
    Mikalsen, I.M.; Breder, Sigurd; Medhus, Asle Wilhelm; Folseraas, Trine; Aabakken, Lars; Ånonsen, Kim Vidar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Aims To evaluate outcomes of ERCP as first-line management in patients with malignant biliary obstruction (MBO) of all causes and stages, reflecting a real-life setting. Methods Retrospective observational study of ...
  • Fatigue: a frequent and biologically based phenomenon in newly diagnosed celiac disease 
    Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Fatigue is increasingly recognized as a major complaint in patients with chronic inflammatory and autoimmune diseases. Although fatigue is assumed to represent a significant problem in celiac disease, existing ...
  • First quality score for referral letters in gastroenterology—a validation study 
    Eskeland, Sigrun Losada; Brunborg, Cathrine; Seip, Birgitte Karen Berggreen; Wiencke, Kristine; Hovde, Øistein; Owen, Tanja; Skogestad, Erik; Huppertz-Hauss, Gert; Halvorsen, Fred-Arne; Garborg, Kjetil Kjeldstad; Aabakken, Lars; de Lange, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Objective To create and validate an objective and reliable score to assess referral quality in gastroenterology. Design An observational multicentre study. Setting and participants 25 gastroenterologists participated in ...