Browsing Institutt for klinisk medisin by Author "A, Bitonti"

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  • Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. 
    Blumberg, Laurence; Humphries, JE; Jones, SD; Pearce, LB; Holgate, R; Hearn, A; Cheung, J; Mahmood, A; Del Tito, B; Graydon, JS; Stolz, LE; A, Bitonti; Purohit, S; de Graaf, D; Kacena, K; Andersen, Jan Terje; Christianson, Gregory J.; Roopenian, DC; Hubbard, Jonathan J.; Gandhi, AK; Lasseter, K; Pyzik, Michal; Blumberg, RS (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglobulin G (IgG). Recently, several clinical studies have reported the lowering of circulating monomeric IgG ...