Browsing Institutt for klinisk medisin by Title
Now showing items 8713-8732 of 10911
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(Doctoral thesis / Doktoravhandling, 2014)
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(Doctoral thesis / Doktoravhandling, 2011)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Host–microbiome interplay from birth is essential for immune imprinting and tuning. Live gut microbes and microbial‐derived metabolites regulate the development and modulation of the immune system, but whether ...
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(Doctoral thesis / Doktoravhandling, 2020)Patients with chronic rhinosinusitis have decreased quality of life. The prevalence of this disease is estimated at above ten percent in some studies. This poses a major socioeconomic challenge. The pathogenesis is still ...
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(Doctoral thesis / Doktoravhandling, 2011)
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)Importance Converging evidence indicates that clusterin, a chaperone glycoprotein, influences Alzheimer disease neurodegeneration. However, the precise role of clusterin in Alzheimer disease pathogenesis is still not well ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Primary sclerosing cholangitis (PSC) is a progressive disease of the bile ducts that usually results in chronic liver disease often requiring liver transplantation. Endoscopy remains crucial to the care of these patients, ...
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(Doctoral thesis / Doktoravhandling, 2009)In order to survive, eukaryotic cells must be in constant communication with the exterior environment. Not only is the cell dependent on the uptake of nutrients and the transmission of metabolic, neuronal and proliferative ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Reactive oxygen and nitrogen species (ROS and RNS, resp.) have been traditionally perceived solely as detrimental, leading to oxidative damage of biological macromolecules and organelles, cellular demise, and ageing. ...
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(Doctoral thesis / Doktoravhandling, 2011)Background: Colorectal cancer (CRC) can be considered a disease of the elderly, with a median age of diagnosis of 72 years. Surgery is the main treatment for colorectal cancer. As chronological age does not accurately ...
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(Doctoral thesis / Doktoravhandling, 2021)Monica Strand and collaborators studied the role of digital support in transitions towards recovery-oriented practices for persons with long-term mental health problems. Few have studied how digital solutions might support ...
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(Doctoral thesis / Doktoravhandling, 2014)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Oral squamous cell carcinoma is an aggressive neoplasm with serious morbidity and mortality, which typically spreads through local invasive growth. Lysophosphatidic acid (LPA) is involved in a ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)The microbiome plays a crucial role in integrating environmental influences into host physiology, potentially linking it to autoimmune liver diseases, such as autoimmune hepatitis, primary biliary cholangitis, and primary ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)One of the major challenges of neonatal intensive care is the early detection and management of circulatory failure. Routine clinicalassessment of the hemodynamic status of newborn infants is subjective and inaccurate, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Optimizing resuscitation is important to prevent morbidity and mortality from perinatal asphyxia. The metabolism of cells and tissues is severely disturbed during asphyxia and resuscitation, and metabolomic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Neurotensin has been found to promote colon carcinogenesis in rats and mice, and proliferation of human colon carcinoma cell lines, but the mechanisms involved are not clear. We have examined ...
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(Doctoral thesis / Doktoravhandling, 2023)Exposure to continually changing endogenous and exogenous stresses exerts selective pressure on bacteria, forcing them to evolve survival strategies. Within the healthcare sector, one particularly stressful condition that ...
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(Doctoral thesis / Doktoravhandling, 2012)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Introduction Regional fat distribution strongly relates to metabolic comorbidities. We identified the DNA repair genes H2AX and HMGB1 to be differentially expressed between human subcutaneous (SAT) and omental visceral ...