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Viser treff 9513-9532 av 10884

  • T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF 
    Abraityte, Judita Aurelija; Aukrust, Pål; Kou, Lei; Anand, Inder S.; Young, James; McMurray, John J.V.; van Veldhuisen, Dirk J.; Gullestad, Lars; Ueland, Thor (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
    Background Activated leukocytes may contribute to the development and progression of heart failure (HF). We investigated the predictive value of circulating levels of stable and readily detectable markers reflecting ...
  • T cell receptor repertoire as a potential diagnostic marker for celiac disease 
    Yao, Ying; Zia, Asima; Neumann, Ralf Stefan; Pavlović, Milena; Balaban, Gabriel; Lundin, Knut Erik Aslaksen; Sandve, Geir Kjetil; Qiao, Shuo Wang (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    An individual's T cell repertoire is skewed towards some specificities as a result of past antigen exposure and subsequent clonal expansion. Identifying T cell receptor signatures associated with a disease is challenging ...
  • T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases 
    Høye, Eirik; Dagenborg, Vegar Johansen; Kristensen, Annette Torgunrud; Lund-Andersen, Christin; Fretland, Åsmund Avdem; Lorenz, Susanne; Edwin, Bjørn von Gohren; Hovig, Eivind; Fromm, Bastian; Inderberg, Else Marit; Greiff, Victor; Ree, Anne Hansen; Flatmark, Kjersti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Background Colorectal liver metastasis (CLM) is a leading cause of colorectal cancer mortality, and the response to immune checkpoint inhibition (ICI) in microsatellite-stable CRC ...
  • T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation 
    McAdam, Stephen N.; Fleckenstein, Burkhard; Rasmussen, Ingunn B; Sandlie, Inger; Bogen, Bjarne; Vinter, N.J.; Sollid, Ludvig Magne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)
    Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to I-A(k) in different conformations. ...
  • T Cell Responses and Regulation and the Impact of In Vitro IL-10 and TGF-beta Modulation During Treatment of Active Tuberculosis 
    Feruglio, Siri; Kvale, Dag; Dyrhol-Riise, Anne Ma (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ...
  • T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis 
    Wolf, Asia-Sophia Fumika Michaela; Ravussin, Anthony; König, Marton; Øverås, Mathias Herstad; Solum, Guri; Kjønstad, Ingrid Fadum; Chopra, Adity; Holmøy, Trygve; Harbo, Hanne-Cathrin Flinstad; Syversen, Silje Watterdal; Jørgensen, Kristin Kaasen; Høgestøl, Einar August; Vaage, John T.; Celius, Elisabeth Gulowsen; Lund-Johansen, Fridtjof; Munthe, Ludvig Andre; Nygaard, Gro Owren; Mjaaland, Siri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Immune responses in people with multiple sclerosis (pwMS) receiving disease-modifying therapies (DMTs) have been of significant interest throughout the COVID-19 pandemic. Lymphocyte-targeting immunotherapies, including ...
  • T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes 
    Ali, Muhammad; Giannakopoulou, Eirini Chrysovalantou; Li, Yingqian; Lehander, Madeleine; Virding Culleton, Stina; Yang, Weiwen; Knetter, Cathrine; Odabasi, Mete Can; Bollineni, Ravi Chand; Yang, Xinbo; Foldvari, Zsofia; Böschen, Maxi-Lu; Taraldsrud, Eli; Strønen, Erlend; Toebes, Mireille; Hillen, Amy; Mazzi, Stefania; de Ru, Arnoud H.; Janssen, George M. C.; Kolstad, Arne; Tjønnfjord, Geir Erland; Lie, Benedicte Alexandra; Griffioen, Marieke; Lehmann, Sören; Osnes, Liv Toril; Buechner, Jochen; Garcia, K. Christopher; Schumacher, Ton N.; van Veelen, Peter A.; Leisegang, Matthias; Jacobsen, Sten Eirik W.; Woll, Petter; Olweus, Johanna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we demonstrate that T cells expressing TCRs specific for ...
  • T-cell Receptor Excision Circles in Newborns with Heart Defects 
    Gul, Kiran Aftab; Strand, Janne Maren; Pettersen, Rolf Dagfinn; Brun, Henrik; Abrahamsen, Tore G (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract In the fetus, the cardiac neural crest gives rise to both the thymus and the conotruncus of the heart. In newborn screening for severe T-cell lymphopenia neonates with congenital heart defects may be detected. In ...
  • T-cell receptors and human leukocyte antigens in primary sclerosing cholangitis 
    Henriksen, Eva Kristine Klemsdal (Doctoral thesis / Doktoravhandling, 2017)
  • T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation 
    Imbery, John Franklin; Heinzelbecker, Julia; Jebsen, Jenny K.; McGowan, Marc Kevin; Myklebust, Camilla Victoria; Bottini, Nunzio; Stanford, Stephanie M.; Skånland, Sigrid S; Tveita, Anders Aune; Tjønnfjord, Geir Erland; Munthe, Ludvig Andre; Szodoray, Peter; Nakken, Britt (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Chronic lymphocytic leukaemia (CLL) is characterised by malignant mature-like B cells. Supportive to CLL cell survival is chronic B-cell receptor (BCR) signalling; however, emerging evidence demonstrates CLL cells proliferate ...
  • T1 bladder cancer in Norway: treatment and survival 
    Blindheim, Augun Jodis; Fosså, Sophie Dorothea; Babigumira, Ronnie; Myklebust, Tor Åge; Haug, Erik Skaaheim; Arum, Carl-Jørgen; Kulle, Bettina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Aim: Evaluation of treatment and survival of pT1 stage (T1) bladder cancer (BC) patients diagnosed with transitional cell carcinoma of the urinary bladder in Norway. Material and methods: According to the Cancer Registry ...
  • T2 weighted MRI and Histopathology as Markers for Response to Somatostatin Analogues in Acromegaly 
    Heck, Ansgar (Doctoral thesis / Doktoravhandling, 2016)
  • Tacrolimus Measured in Capillary Volumetric Microsamples in Pediatric Patients—A Cross-Validation Study 
    Kindem, Ingvild Andrea; Bjerre, Anna Kristina; Åsberg, Anders; Midtvedt, Karsten; Bergan, Stein; Vethe, Nils Tore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background: Therapeutic drug monitoring of tacrolimus (Tac) is mandatory in solid organ transplant (SOT) recipients. Finger-prick microsampling is more flexible and tolerable during the therapeutic drug monitoring of ...
  • Tailored surgery in chronic pancreatitis after implementation of a multidisciplinary team assessment; a prospective observational study 
    Waage, Anne; Holmquist, Olof Dan Sebastian; Labori, Knut Jørgen; Paulsen, Vemund; Aabakken, Lars; Lenz, Harald; Felix Magnus, Henrik C.; Tholfsen, Tore; Hauge, Truls (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Introduction Optimal management of chronic pancreatitis involves several specialties. Selection of patients for surgery may benefit from evaluation by a multidisciplinary team (MDT), similar to cancer care. The aim of ...
  • Take-Home Naloxone Kits: Attitudes and Likelihood-Of-Use Outcomes from a European Survey of Potential Overdose Witnesses 
    McDonald, Rebecca; Breidahl, Sibella; Abel-Ollo, Katri; Akhtar, Shabana; Clausen, Thomas; Day, Ed; Kelleher, Mike; McAuley, Andrew; Petersen, Helle; Sefranek, Martin; Thiesen, Henrik; Strang, John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background: Injectable naloxone is already provided as take-home naloxone (THN), and new concentrated intranasal naloxone is now being introduced in Europe. Despite evidence of the effectiveness and cost-effectiveness of ...
  • "Takk som spør" : En kvalitativ studie om hvordan barnevernet oppleves av barn og ungdom som har levd med vold i familien 
    Steen, Tonje (Master thesis / Masteroppgave, 2012)
    Denne masteroppgaven handler om hvordan barnevernet oppleves av barn og ungdom som har levd med vold i familien. Oppgaven er basert på kvalitative intervjuer, og temaene som barna har vektlagt er analysert i lys av lovverk ...
  • TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration 
    Lagström, Sonja; Umu, Sinan Uğur; Lepistö, Maija; Ellonen, Pekka; Meisal, Roger; Christiansen, Irene Kraus; Ambur, Ole Herman; Rounge, Trine Ballestad (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effective sequencing ...
  • Tanker om overlevelse : Flyktningers refleksjoner om styrkende faktorer i et liv med traumehendelser 
    Sandvik, Hedda (Master thesis / Masteroppgave, 2012)
    Flyktninger har som regel en historie som handler om ekstreme påkjenninger, ulike tap, forfølgelse, tvungen migrasjon og en utfordrende eksiltilværelse. Det er kjent at det å bli utsatt for ekstreme hendelser øker sårbarheten ...
  • Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models 
    Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Mahmuda, Shoshy (Brinch, Shoshy Alam); Lycke, Eric Maximilian; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre; Krauss, Stefan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    The development of immune checkpoint inhibitors represents a major breakthrough in cancer therapy. Nevertheless, a substantial number of patients fail to respond to checkpoint pathway blockade. Evidence for WNT/β-catenin ...
  • Tapering from Methadone or Buprenorphine during Pregnancy: Maternal and Neonatal Outcomes in Norway 1996-20 
    Welle-Strand, Gabrielle; Skurtveit, Svetlana; Tanum, Lars; Waal, Helge; Bakstad, Britt Elise; Bjarkø, Lisa; Ravndal, Edle (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
    Background: The tapering of methadone or buprenorphine during pregnancy is an understudied and controversial issue. The aim of this study was to determine to what extent women tapered their opioid medication dose during ...