Browsing Molekylærbiologi by Issue Date
Now showing items 1-20 of 308
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(Master thesis / Masteroppgave, 2013)Cytokinesis is the final step of cell division that leads to the physical separation of two daughter cells by abscission. It is now well established that several components of endosomal machineries are involved in cytokinesis ...
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(Master thesis / Masteroppgave, 2013)The WEE1-inhibitor MK-1775 is currently in clinical trials as an anti-cancer drug. In response to DNA damage, human cells activate cell cycle checkpoints to temporarily halt cell cycle progression, and this helps facilitating ...
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The potential of tumor-specific Th2 cells for cancer immunotherapy by adoptive transferRestricted Access (Master thesis / Masteroppgave, 2013)Immunotherapy based on adoptive cell transfer (ACT) of tumor-specific T cells, either naturally occurring or gene engineered, represents a promising strategy to cure cancer. To date the majority of ACT trials have focused ...
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(Master thesis / Masteroppgave, 2013)RNA pyrophosphohydrolase (RppH) catalyzes the removal of pyrophosphate from 5' triphosphorylated RNAs thereby initiating RNA degradation. The enzyme has originally been identified in bacteria but homologs are present in ...
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(Master thesis / Masteroppgave, 2013)
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Phage library against library for combinatorial discovery of matched target and bait pairs - a proof of principleRestricted Access (Master thesis / Masteroppgave, 2013)
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Expanding the c-Myb interaction network through search for and studies of novel interaction partnersRestricted Access (Master thesis / Masteroppgave, 2013)SUMMARY The transcription factor c-Myb is a key regulator of stem- and progenitor cells in the bone marrow, which has the task of forming most of the blood cells. However, maturation, activation and some proliferation of ...
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Human albumin-antigen fusions with improved FcRn binding and transport propertiesRestricted Access (Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2013)Iron oxide nanoparticles are widely used for magnetic resonance imaging, and there is a rapidly expanding research interest in using these nanoparticles for drug delivery or cell labeling. Therefore we need a better ...
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A novel role for the PNUTS/PP1 interacting proteins WDR82 and TOX4 in the DNA damage responseRestricted Access (Master thesis / Masteroppgave, 2013)
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Differential effects of bone morphogenetic proteins (BMPs) in human memory B cellsRestricted Access (Master thesis / Masteroppgave, 2013)
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Utilization of autophagy in the antigen donor cell for enhanced priming of Gag-p24-specific CD8+ T cell responsesRestricted Access (Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2013)Steroide hormone receptors (SHRs) are ligand-modulated transcription factors that regulate important physiological processes. The effects of SHRs are regulated by their coordinated interaction with other transcription ...
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(Master thesis / Masteroppgave, 2013)Prostate cancer (PCa) is the most common type of cancer among men in Western countries. An approach to better PCa diagnosis, prognosis and management is to identify genes that are prostate-specific and differentially ...
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Aberrant m6A regulation in Alkbh5 deficient mice results in increased DNA methylation and altered gene expressionRestricted Access (Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2013)The Casitas B-lineage lymphoma (Cbl) family of ubiquitin ligases has been studied for years regarding their important role in downregulation of ligand bound epidermal growth factor receptor (EGFR). The two isoforms c-Cbl ...
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The Effect of Transcorneal Electrical Stimulation on the Electroretinogram in Patients with Retinitis PigmentosaRestricted Access (Master thesis / Masteroppgave, 2013)Retinitis Pigmentosa (RP) is a progressive and degrading illness impairing the vision of all age groups [1-3]. The disease is caused by mutations which are affecting the photoreceptors and the retinal pigment epithelium ...