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Plasma-derived exosomes as potential biomarkers for pediatric acute leukemia. 
Sørensen, Eva Mjåseth (Master thesis / Masteroppgave, 2020)
The purpose of this study was to find whether exosomes can function as biomarkers for acute leukemia in children, with the long-term goal to assess whether exosomes can be used to predict risk of relapse.
Synergia PRR-fecta: Harnessing pathogen-recognition receptor synergy to produce high levels of IL-12p70 & prime dendritic cells for use in cancer immunotherapy Restricted Access
Gilmour, Brian Christopher (Master thesis / Masteroppgave, 2020)
Progress in the production of consistent, viable anti-cancer vaccines has been hampered by the lack of a fitting adjuvant capable of eliciting a targeted, cytotoxic response against tumours. The cytokine interleukin 12p70 ...
Characterization of human and chicken PGM2 and PGM5 Restricted Access
Dahl, Anette Kathinka (Master thesis / Masteroppgave, 2020)
The proteins of the α-D-phosphohexomutase superfamily are important in several metabolic processes in all kingdoms of life. Many of the superfamily members are, however, severely understudied. Two of the less studied human ...
Increasing the efficacy of influenza vaccination in obese individuals Restricted Access
Klausen, Kristin Lunder (Master thesis / Masteroppgave, 2020)
Idiotype-specific Th cells as a drive for the expansion of malignant B cells in chronic lymphocytic leukemia Restricted Access
Lund, Katrine Persgård (Master thesis / Masteroppgave, 2020)
Microbiological monitoring of an Atlantic salmon recirculating aquaculture system (RAS) – Health and quality assessment 
Banaszkiewicz, Maria (Master thesis / Masteroppgave, 2020)
Aquaculture is an important industry in Norway, particularly the production of Atlantic salmon (Salmo salar L.). Health problems and environmental impacts during the seawater stage are limiting factors for the industry. ...
Development of novel human antibodies targeting T cells 
Våg, Ingeborg (Master thesis / Masteroppgave, 2020)
Acinetobacter baumannii in Norwegian chicken farms: A One Health perspective Restricted Access
Edvardsen, Per Kristian Thorén (Master thesis / Masteroppgave, 2020)
The Gram-negative bacterium, Acinetobacter baumannii, is one of the leading causes of drug resistant hospital-acquired infections in humans. Owing to its ability to easily acquire resistance genes and to survive in the ...
A novel trimeric APC targeted DNA vaccine against influenza Restricted Access
Brown, Diamond Whitney (Master thesis / Masteroppgave, 2020)
Antibody-targeted photodynamic therapy to kill cancer cells Restricted Access
Gebretensaie, Samrawit Michael (Master thesis / Masteroppgave, 2020)
Mechanisms controlling the selection of anti-transglutaminase 2 B cell receptors in celiac disease 
Das, Saykat (Master thesis / Masteroppgave, 2019)
Production of autoantibodies by TG2-specific gut plasma cells is a hallmark of celiac disease. Previous studies have revealed biased selection of IGHV and IGKV gene segments, low number of mutations and preferential targeting ...
Identification and Functional Characterization of microRNAs in Ichthyosporea Restricted Access
Zhu, Hengyi (Master thesis / Masteroppgave, 2019)
microRNAs (miRNAs) are short RNA molecules, which post-transcriptionally regulate other genes. They are generated from genome-encoded single-stranded hairpin structures, by a set of RNA-processing enzymes. miRNAs are highly ...
Effects of the mycotoxin Deoxynivalenol and grain components on intestinal in vitro model systems Restricted Access
Wolden, Johanne Kristin Lied (Master thesis / Masteroppgave, 2019)
Characterization of eIF2α kinases in prostate cancer cells Restricted Access
Frengen, Nicolai Sebastian (Master thesis / Masteroppgave, 2019)
Cancer is the second leading cause of death worldwide. In Norwegian men, prostate cancer (PCa) was the most commonly diagnosed cancer and second most frequent cause of cancer death in 2017. The tumor microenvironment (TME), ...
Identification and validation of putative pathogenic variants in a patient with intellectual disability, epilepsy, autism and macrocephaly 
Zohoorian Izadpanah, Negar (Master thesis / Masteroppgave, 2019)
Whole exome sequencing was performed to identify putative disease-causing variants in a girl with macrocephaly, epilepsy and severe mental retardation, who had an unknown molecular diagnosis. Compound heterozygous SZT2 ...
Exploring FLT3 driven acute myeloid leukemia for novel immunotherapeutic options. 
Abono, Desmond Mfua (Master thesis / Masteroppgave, 2019)
Acute myeloid leukemia (AML) is one of the subtypes of leukemia that is genetically and medically heterogeneous. The FLT3-ITD mutant variant is one of its form of leukemia, that constitutes 30% of the occurrences. This ...
PCI-based Targeted Therapy for Treatment Resistant Sarcoma 
Czachorowski, Abriel Malin (Master thesis / Masteroppgave, 2019)
Sarcomas arise in patients of all ages and account for approximately 1% of new cancer diagnoses in Norway and the United States. Osteosarcoma is a subtype of sarcoma that typically affects children and adolescents and ...
Small molecule c-Myc modulator as a potential compound for immunotherapeutic treatment of cancers Restricted Access
Chlubnová, Markéta (Master thesis / Masteroppgave, 2019)
Development of Novel Treatments for Drug-Resistant Candida Infections Restricted Access
Corrales, Jeanne Gaspar (Master thesis / Masteroppgave, 2019)
The EEG Slow Wave Activity; a possible marker for consciousness 
Hasanzadehmoghadam, Fatemeh (Master thesis / Masteroppgave, 2019)
VH315 Heavy Chain Shows Preference for VL Lambda over VL Kappa Light Chain Partners 
Randjelovic, Kristina (Master thesis / Masteroppgave, 2019)
Molecular Mechanism of Hairpin Formation and Passenger Secretion in the Inverse Autotransporter Intimin 
Kandanur, Sai Priya Sarma (Master thesis / Masteroppgave, 2019)
Gram-negative bacteria use different protein secretion systems, ranging from type I through type IX, to invade the host and cause infections. Proteins of the type V secretion system, called autotransporters, can autonomously ...
Association between plasma glucose in pregnancy and DNA methylation of candidate CpG sites Restricted Access
Kiryushchenko, Nadezhda (Master thesis / Masteroppgave, 2019)
Background: Increased plasma glucose levels in pregnancy or gestational diabetes may have implications for future maternal health, such as increased risk of type 2 diabetes mellitus (T2DM) developing within 10 years. ...
Molecular heterogeneity in multifocal primary prostate cancer Restricted Access
Kidd, Susanne Gundersen (Master thesis / Masteroppgave, 2019)
Repeated social defeat induces changes in splenic myeloid cells: downregulation of β-arrestin-2 and upregulation of IL-6 Restricted Access
Nymoen, Ingeborg (Master thesis / Masteroppgave, 2019)
TREM2: A potential target for treatment of Alzheimer’s Disease Restricted Access
Johannesen, Brage Milch (Master thesis / Masteroppgave, 2019)
Emblica officinalis as a therapeutic supplement in Alzheimer’s disease 
Chilcutt, Natalie Lane (Master thesis / Masteroppgave, 2019)
Alzheimer’s disease (AD) is the most common form of dementia, currently affecting 50 million people worldwide. While plaques of misfolded protein amyloid-beta (Aβ) are a hallmark of the disease, drugs targeted to reduce ...
A proteomics-based approach to identify interactors of the IDA-HAE/HSL2 signaling pathway Restricted Access
Mertes, Verena (Master thesis / Masteroppgave, 2019)
Mechanism of SUMO repression of the transcription factor c-Myb – the role of SUMO acetylation 
Haug, Andrea (Master thesis / Masteroppgave, 2019)
Role of NEIL DNA glycosylases in G4 dynamics Restricted Access
Pannone, Marco (Master thesis / Masteroppgave, 2019)
Gene activation and SUMO-derepression through HIPK1-mediated p300 phosphorylation 
Rijal, Pradip (Master thesis / Masteroppgave, 2019)
Determining the clonal composition and antigen specificity of germinal center regulatory T cells Restricted Access
Solem, Sigrid Kinden (Master thesis / Masteroppgave, 2019)
Identification of novel DNA methylation biomarkers for kidney cancer Restricted Access
Børresen, Ida Marie (Master thesis / Masteroppgave, 2019)
Endoplasmic reticulum stress downregulates c-MYC expression through proteasomal degradation in prostate cancer cells Restricted Access
Steward, Hannah Jaer (Master thesis / Masteroppgave, 2019)
Prostate cancer (PCa) is the most prevalent non-cutaneous cancer and second leading cause of cancer-related death among men in Western countries. Knowledge of its underlying molecular mechanism is necessary to characterise ...
Identification of a novel interacting partner of Rab33b: a potential link to cell migration Restricted Access
Bjørnestad, Synne Arstad (Master thesis / Masteroppgave, 2019)
Characterization of the role of a Rab protein in cell migration through novel interactors Restricted Access
Berg, Sigmund Eystein (Master thesis / Masteroppgave, 2019)
Identification and pre-clinical assessment of patient-derived TCRs for solid tumor immunotherapy Restricted Access
Ruud, Amanda Malene (Master thesis / Masteroppgave, 2019)
Can activation of the lactate receptor HCAR1 by lactate injections influence disease development in an animal model for Alzheimer’s disease? 
Belhaj, Imen (Master thesis / Masteroppgave, 2019)
Improved biomarker potential of long non-coding RNAs in multisampled primary prostate cancer Restricted Access
Olsen, Linn Guro (Master thesis / Masteroppgave, 2019)
Characterization of a Drosophila model of MLL-rearranged leukemia Restricted Access
Bråthen, Nora Rojahn (Master thesis / Masteroppgave, 2019)
Studying the Impact of Drugs on LINE-1 Retrotransposition Restricted Access
Mustorp, Guro Cecilie (Master thesis / Masteroppgave, 2019)
Dissecting the transactivation domain of the transcription factor c-Myb 
Storesund, Jan Ove (Master thesis / Masteroppgave, 2019)
Dissecting the Transactivation Domain of the Transcription Factor c-Myb 
Næs, Guro (Master thesis / Masteroppgave, 2019)
Dissecting the Transactivation Domain of the Transcription Factor c-Myb 
Udayakumar, Priyanga-Dina (Master thesis / Masteroppgave, 2019)
Identification of novel molecular targets in drug resistant fungi 
Sønsterud, Linda Håkensbakken (Master thesis / Masteroppgave, 2019)
Human IgG subclasses in intracellular antiviral immunity Restricted Access
Jonsson, Alexandra (Master thesis / Masteroppgave, 2018)
Immune exhaustion of T cells in HIV+ immunological nonresponders Restricted Access
Handeland, Charlotte Andrea Hauge (Master thesis / Masteroppgave, 2018)
Characterization of a peptide-Fc fusion protein Restricted Access
Pettersen, Solveig (Master thesis / Masteroppgave, 2018)
The microenvironment as the basis of CLL cell growth - Defining pathways, enabling EBV transformation and performing groundwork for drug sensitivity screening of patients Restricted Access
Subbanna, Sowmya (Master thesis / Masteroppgave, 2018)
Chronic lymphocytic leukemia (CLL) is a mature B-cell malignancy that most often affects the elderly. CLL cells depend on their microenvironment for their extended growth and survival. CLL cells are difficult to grow “in ...
Effects of Hsp90 inhibition and/or PKC activation on ErbB2 in MDA-MB-453 cells 
Chitano, Ylenia (Master thesis / Masteroppgave, 2018)
ErbB2 is one of the four members of the epidermal growth factor family of receptor tyrosine kinases, which mediate the activation of several signaling pathways that lead to cell proliferation, survival, differentiation and ...
Regulation of translation after exposure to stress 
Pettersen, Vilde Emilie (Master thesis / Masteroppgave, 2018)
When encountering environmental stress, cells alter their gene expression pattern which primarily occurs at translational level. This leads to rapid changes in the protein repertoire, making the cells more able to adapt ...
STAMP2 Affects Stress Signaling Events in Prostate Cancer Cells Restricted Access
Vallenari, Evan Michael (Master thesis / Masteroppgave, 2018)
The Impact of Persistent Organic Pollutants on Neural Development Using an In Vitro Approach 
Davidsen, Nichlas (Master thesis / Masteroppgave, 2018)
Persistent Organic Pollutants (POPs) are highly stable chemicals that are widespread in nature with potential hazardous effects in humans and wildlife. POPs have been used in a multitude of industrial applications and ...
Co-aggregation Properties of trimeric autotransporter adhesins 
Khalil, Hawzeen Salah Khalil (Master thesis / Masteroppgave, 2018)
Localization of a putative RNA pyrophosphohydrolase in the unicellular green alga Chlamydomonas reinhardtii Restricted Access
Yaghoobi Nezhad, Maral (Master thesis / Masteroppgave, 2018)
In bacteria an RNA pyrophosphohydrolase (RppH) has been shown to remove pyrophosphate (PPi) from the 5’ end of mRNAs thereby allowing binding of RNases that degrade the transcripts. In previous master projects a gene that ...
Functional characterization of three members of the NEDD4 family of E3 ubiquitin ligases in the regulation of connexin43 Restricted Access
Basing, Sebastian (Master thesis / Masteroppgave, 2018)
Fibroblast-Mediated Resistance to BRAF Inhibition in Metastatic Melanoma - Effect of drugs targeting PI3K/AKT/mTOR signaling pathway 
Gawraczynska, Marta (Master thesis / Masteroppgave, 2018)
In vitro measurements of immunogenic cell death after radiation treatment combined with ATR inhibition: Potential effects on anti-cancer immunity Restricted Access
Mariampillai, Adrian Eek (Master thesis / Masteroppgave, 2018)
Nanoparticle-mediated drug therapy against tuberculosis in the zebrafish embryo model 
Dal, Nils-Jørgen Knudsen (Master thesis / Masteroppgave, 2018)
Mycobacterium tuberculosis (M.tb), the primary agent of human tuberculosis (TB), is a global problem of pandemic dimensions, despite the introduction of antibiotics against the disease happened more than 70 years ago. Today ...
Xenograft in zebrafish embryo's neural tube: A preclinical model for studying nanoparticle-mediated drug delivery to tumors Restricted Access
Kocere, Agnese (Master thesis / Masteroppgave, 2018)
The Role of the Transcription Factor Ikaros in Acute Myeloid Leukemia and Myeloid Development Restricted Access
Vestbøstad, Johanne (Master thesis / Masteroppgave, 2018)
Discovery of small-molecule inhibitors of human endonuclease VIII-like 1 (NEIL1) Restricted Access
Hansen, Ane-Sofie Bednarczyk (Master thesis / Masteroppgave, 2018)
Epigenetic alterations associated with EMT within ER positive breast cancers Restricted Access
Ankill, Jørgen (Master thesis / Masteroppgave, 2018)
Breast cancer is the most prevalent type of cancer affecting females in world today and poses a serious public health problem worldwide. Even though the overall survival has increased significantly the last decades, the ...
Characterisation of the immune contexture of breast cancer subtypes Restricted Access
Torland, Lilly Anne (Master thesis / Masteroppgave, 2018)
Purpose: The purpose and aim of this project was to investigate immune contexture according to tumour molecular subtype, and ER status. To find the interrelationship between serum cytokine levels and specific tumour cell ...
Cell- and genome size responses to different temperatures in haptophytes 
Standeren, Erik (Master thesis / Masteroppgave, 2018)
In recent years, environmental concerns and global temperature increase has attracted a wide interest. Global temperature has increased in the recent years, and will continue to do so in the near future. How organisms, ...
Cholera toxin and cytolethal distending toxin: Expression, purification and stability with host machineries 
Tveitan, Siri Luise (Master thesis / Masteroppgave, 2018)
Very young women with breast cancer - Unique biology? 
Ladegård, Marie Kristine Lizcano (Master thesis / Masteroppgave, 2017)
Dissecting the direct projection from the medial septum to the grid cell network 
Frey, Mina Martine (Master thesis / Masteroppgave, 2017)
The medial entorhinal cortex (MEC) spatially modulated neurons, including grid cells, all contribute to the brain's spatial navigation system. The mechanisms behind the grid cells' hexagonal firing pattern in space remain ...
Analysis of the role of four members of the NEDD4 family of E3 ubiquitin ligases in the modulation of growth characteristics of LoVo colon cancer cells Restricted Access
Five, May-Britt (Master thesis / Masteroppgave, 2017)
The role of diacylglycerol kinase α in retrograde transport Restricted Access
Thiyagarajah, Shakiththiya (Master thesis / Masteroppgave, 2017)
Design and characterization of IgG variants fused to albumin domain III Restricted Access
Mester, Simone (Master thesis / Masteroppgave, 2017)
Combination Treatments to Overcome Fibroblast-Associated Resistance to BRAF Inhibitors in Malignant Melanoma Use of the PeggySue Technology to Explore Drug Responses at a Protein level 
Jørgensen, Kjetil (Master thesis / Masteroppgave, 2017)
Malignant melanomas are one of the most devastating forms of cancers with high mortality rate. The melanoma cells readily spread to distant organs, where the cancer cells interact with stromal cells. Such interaction can ...
Metformin as an anticancer agent: Combining Metformin with the tankyrase inhibitor G007-LK for treatment of NSCLC Restricted Access
Johnsen, Ida (Master thesis / Masteroppgave, 2017)
O-linked glycosylation in Neisseria meningitidis. A study of glycan diversity, glycoproteome and immunogenic properties. Restricted Access
Herø, Elin Christine Eliassen (Master thesis / Masteroppgave, 2017)
Phenotypic changes following upregulation of miR-105-5p, miR-767-5p and miR-6499-5p in SW756 cervical cancer cells Restricted Access
Gjølberg, Torleif Tollefsrud (Master thesis / Masteroppgave, 2017)
A Novel Signaling Pathway that Regulates Cell Adhesion in Prostate Cancer Restricted Access
Haukanes, Benedikte (Master thesis / Masteroppgave, 2017)
Developing a platform for the study of multifactorial diseases 
Ingebrigtsen, Stian Eide (Master thesis / Masteroppgave, 2017)
Investigation of DNA and RNA changes in multifocal prostate cancer - Identification of novel alterations and molecular subtyping of individual tumors Restricted Access
Carm, Kristina Totland (Master thesis / Masteroppgave, 2017)
The role of MITF in the regulation of CDKN2A in melanoma 
Andreassen, Randi Christel (Master thesis / Masteroppgave, 2017)
Melanoma is the deadliest form of skin cancer when discovered in advanced stages. Early detection with surgical tumor removal is still the most effective treatment option. Novel treatment options such as small molecular ...
Production and Purification of Membrane Scaffold Protein and Class IID bacteriocin Enterocin EJ97 from Enterococcus faecalis EJ97 
Chaudhary, Mahendra (Master thesis / Masteroppgave, 2017)
Characterization of a Novel Human Methyltransferase Restricted Access
Zuhairi, Fawzi Rahmadiyan (Master thesis / Masteroppgave, 2017)
Methylation is the transfer of a methyl group from a methyl donor to a substrate, and such reactions are catalyzed by enzymes called methyltransferases (MTases). The methyl donor for cellular methylation reactions is most ...
Hippocampal ROS and mitochondria in exercise: an electron microscopy analysis in a rat model of aerobic fitness Restricted Access
Moretti, Laura (Master thesis / Masteroppgave, 2017)
In humans, objectively measured cardiovascular fitness is a good predictor of cognitive performance and of the risk to suffer from dementia. This association remains to be explained mechanistically, but altered mitochondrial ...
Inhibering av reseptor tyrosin kinase AXL i melanoma celler ved bruk av BGB324 
Omar, Nasrin (Master thesis / Masteroppgave, 2017)
Identification of potential adhesin receptors for Yersinia ruckeri: expression and purification of Yersinia ruckeri Invasin Restricted Access
Liskiewicz, Krystyna Anna (Master thesis / Masteroppgave, 2017)
Yersinia ruckeri is a causative agent of yersiniosis or enteric redmouth disease (ERM) in salmonid fish. It leads to significant economic losses in fish aquaculture industry each year. The exact virulence mechanism and ...
Role of microRNA-223 in pain modulation 
Legfeldt, Anna (Master thesis / Masteroppgave, 2017)
Identifying protein interaction partners for DEXI, encoded by the multiple sclerosis associated dexamethasone-induced gene, DEXI 
Mo, Ingrid (Master thesis / Masteroppgave, 2017)
Molecular characterization of T-cell activation Rho-GTPase activating protein 
Kropf Correia, Fernanda (Master thesis / Masteroppgave, 2017)
Identification of DNA methylation biomarkers for gastrointestinal cancer - Ubiquitin C-terminal hydrolase L1 (UCHL1) 
Güere, Mariella Evelyn (Master thesis / Masteroppgave, 2017)
Stim1 p.R304 mutations may cause constitutive puncta formation in murine cells Restricted Access
Reinseth, Ingvild Sveum (Master thesis / Masteroppgave, 2017)
Developing cancer immunotherapy by activating macrophage tumoricidal activity 
Avdagic, Ajna (Master thesis / Masteroppgave, 2017)
High Resolution Mapping of Prostaglandin E2 Signaling Pathways in T cell Subsets Restricted Access
Jørgensen, Marthe Jøntvedt (Master thesis / Masteroppgave, 2017)
Functional evaluation of polo like kinase 1 (PLK1), a potential drug target, in malignant peripheral nerve sheath tumor cells Restricted Access
Thorsen, Marthe Norreen (Master thesis / Masteroppgave, 2017)
Elucidation of the function of CW-MBD proteins of Arabidopsis thaliana - A potential role in light-mediated processes Restricted Access
Iversen, Vegard (Master thesis / Masteroppgave, 2017)
Functional Analysis of Stress Signaling in Prostate Cancer Cells Restricted Access
Livgård, Marte (Master thesis / Masteroppgave, 2016)
RNAseq analysis identifies differentially expressed genes of Serpula lacrymans during growth on Scots pine and Norway spruce wood 
Bakkemo, Reneè Isabel (Master thesis / Masteroppgave, 2016)
Evaluation of WMircrotracker for assessing C. elegans stress responses 
Zhu, Hengyi (Master thesis / Masteroppgave, 2016)
Nanoparticle delivery of anti-tuberculosis drugs Formulation and testing of clofazimine containing nanoparticles using a zebrafish embryo tuberculosis model 
Høgset, Håkon (Master thesis / Masteroppgave, 2016)
The role of perineuronal nets in spatial memory 
Olsen, Katrine Haram (Master thesis / Masteroppgave, 2016)
The interaction between the hippocampus and parahippocampal region is essential for the processing and storage of episodic memories. Spatial memory is a form of episodic memory, which entails the details of the what, when ...
Developing a Molecular Approach to Determine the Last Blood Meal in Ticks 
Mjønes, Caroline Skar (Master thesis / Masteroppgave, 2016)
How does antibody-virus affinity affect TRIM21-mediated protection? Restricted Access
Lode, Heidrun Elisabeth (Master thesis / Masteroppgave, 2016)
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