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Now showing items 1-100 of 2157
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
A growing body of evidence suggests that processes of upward treeline expansion and shifts in vegetation zones may occur in response to climate change. However, such shifts can be limited by a variety of non-climatic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Marine threespine sticklebacks colonized and adapted to brackish and freshwater environments since the last Pleistocene glacial. Throughout the Holarctic, three lateral plate morphs are observed; ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)
Sperm morphological traits are highly variable among species and are commonly thought to evolve by post-copulatory sexual selection. However, little is known about the evolutionary dynamics of sperm morphology, and whether ...
(Master thesis / Masteroppgave, 2018)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Understanding the effects of habitat modification on the feeding strategies of threatened species is essential to designing effective conservation management plans. Bale monkeys (Chlorocebus ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Most suids (Mammalia: Suidae, pigs) worldwide are omnivores living in closed environments, but the African warthog (Phacochoerus) has special adaptations for grazing in open environments. Similar specializations have been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Signalling proteins often contain several well defined and conserved protein domains. Structural analyses of such domains by nuclear magnetic spectroscopy or X-ray crystallography may greatly inform the function ...
(Master thesis / Masteroppgave, 2020)
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Forest loss and degradation are the most significant threats to terrestrial biodiversity in the tropics. Promoting flagship or umbrella species is a strategy that can be used to conserve intact forests and restore degraded ...
Understanding the role of RNA binding protein QKI in the regulation of H2A.Z variants in breast cancer Restricted Access
(Master thesis / Masteroppgave, 2020)
Breast cancer is the most predominant form of cancer in females worldwide. High throughput gene expression analysis has led to classification of breast cancer into distinct molecular subtypes (Parker et al., 2009; Perou ...
(Doctoral thesis / Doktoravhandling, 2018)
The genomic landscape of a hybrid species is marked by alternating regions of parental inheritance and areas of genomic constraint which form reproductive barriers.
A PhD candidate at the University of Oslo has explored ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Ongoing climate change threatens biodiversity and directly affects the stability of plant-animal communities. However, it is unclear how the species diversity of biological communities responds to natural climate warming, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Understanding the genetic basis of adaptation is one of the main enigmas of evolutionary biology. Among vertebrates, hemoglobin has been well documented as a key trait for adaptation to different environments. Here, we ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background Functionality of the tetrameric hemoglobin molecule seems to be determined by a few amino acids located in key positions. Oxygen binding encompasses structural changes at the interfaces between the α1β2 and α2β1 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Closely related transcription factors (TFs) can bind to the same response elements (REs) with similar affinities and activate transcription. However, it is unknown whether transcription is similarly orchestrated by different ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
This paper reports a full assessment of results from ICON, an international workshop on marine integrated contaminant monitoring, encompassing different matrices (sediment, fish, mussels, gastropods), areas (Iceland, North ...
(Doctoral thesis / Doktoravhandling, 2013)
Mennesker har i lang tid forvaltet hjortevilt for ulike formål som mat, troféer eller bestandsregulering. Forvaltningen foregår gjennom ulike former for selektiv jakt. Pga. alders- og kjønnsspesifikke kvoter og jegernes ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Partial migration is common among northern ungulates, typically involving an altitudinal movement for seasonally migratory individuals. The main driving force behind migration is the benefit of an extended period of access ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Postzygotic isolation in the form of reduced viability and/or fertility of hybrids may help maintain species boundaries in the face of interspecific gene flow. Past hybridization events between ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
The ballan wrasse (Labrus bergylta) belongs to a large teleost family containing more than 600 species showing several unique evolutionary traits such as lack of stomach and hermaphroditism. ...
(Master thesis / Masteroppgave, 2022)
Cardiovascular disease (CVD) is a major contributor to both mortality and disability worldwide, with numbers of cases continuously rising. While CVD is commonly thought to primarily affect men, it is a main killer amongst ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The importance of forests of the kelp Laminaria hyperborea along the Norwegian coast is related to the three dimensional structure that they create together with the associated macroalgae. Today, kelp forests have recovered ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The Barents Sea system is often depicted as a simple food web in terms of number of dominant feeding links. The most conspicuous feeding link is between the Northeast Arctic cod Gadus morhua, the world's largest cod stock ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Teleosts are exposed to a broad range of external stimuli, which may be either of acute or chronic nature. The larval phase of certain fish species offer a unique opportunity to study the ...
(Doctoral thesis / Doktoravhandling, 2015)
(Master thesis / Masteroppgave, 2022)
(Doctoral thesis / Doktoravhandling, 2018)
Skeletal muscle is a heterogeneous tissue comprised of a variety of different cell types, including the multinucleated skeletal myofiber. Although myofibers are post-mitotic, they hold a remarkable ability to adapt new ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
The class Diphyllatea belongs to a group of enigmatic unicellular eukaryotes that play a key role in reconstructing the morphological innovation and diversification of early eukaryotic evolution. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Gillnet sampling and analyses of otolith shape, vertebral count and growth indicated the presence of three putative Atlantic herring (Clupea harengus L.) populations mixing together over the spawning season February–June ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Clostridium botulinum comprises a diverse group of botulinum toxin-producing anaerobic rod-shaped spore-forming bacteria that are ubiquitously distributed in soils and aquatic sediments. Decomposition of plants, algae, and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Most cervid populations in Europe and North America are managed through selective harvesting, often with age- and sex-specific quotas, with a large influence on the population growth rate. Less well understood is how ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Next generation sequencing of ribosomal DNA is increasingly used to assess the diversity and structure of microbial communities. Here we test the ability of 454 pyrosequencing to detect the number of species present, and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Rural livelihoods relying on agriculture are particularly vulnerable to climate change. Climate models project increasingly negative effects on maize and sorghum production in sub-Saharan Africa. We present a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background
Plague (Yersinia pestis infection) is a vector-borne disease which caused millions of human deaths in the Middle Ages. The hosts of plague are mostly rodents, and the disease is spread by the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Many wingless ectoparasites have a limited capacity for active movement and are therefore primarily dependent on hitchhiking on their hosts for transportation. The distribution of the tick Ixodes ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Maize is the most produced crop in Sub-Saharan Africa, but yields are low and climate change is projected to further constrain smallholder production. The current efforts to breed and disseminate new high ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Freshwater fishes of the genus Esox are found throughout the Holarctic region. The northern pike (E. lucius) has a circumpolar distribution whereas the assumed sister species the Amur pike (E. reichertii) is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Ticks and tick-borne diseases are increasing in many areas of Europe and North America due to climate change, while land use and the increased abundances of large hosts play a more controversial role. The pattern ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Divergent selection pressures induced by different environmental conditions typically lead to variation in life history, behavior, and morphology. When populations are locally adapted to their current environment, selection ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Salinity is one of the key factors that affects metabolism, survival and distribution of fish species, as all fish osmoregulate and euryhaline fish maintain osmotic differences between their extracellular fluid and either ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The vertical distribution and migration of plankton organisms may have a large impact on their horizontal dispersal and distribution, and consequently on trophic interactions. In this study we used video-net profiling to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
It is generally accepted that the high buoyancy of pelagic marine eggs is due to substantial influx of water across the cell membrane just before ovulation. Here we further develop the theoretical basis by applying laboratory ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Strictly speaking, fundamental niches are inestimable. Nevertheless, ecologists attempt approximating them to understand species ’ distribution and plasticity to environmental changes, with invaluable repercussions on both ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Large carnivores that approach human settlements are usually considered a threat to human property and safety. The prevailing paradigm, that such ‘problem’ animals approach settlements in search of food, ignores their ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Abundant new ichthyosaur material has recently been documented in the Slottsmøya Member of the Agardhfjellet Formation from the Svalbard archipelago of Norway. Here we describe a partial skeleton of a new taxon, Janusaurus ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background Advances in sequencing efficiency have vastly increased the sizes of biological sequence databases, including many thousands of genome-sequenced species. The BLAST algorithm remains the main search engine for ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Harvest control rules (HCRs) have been implemented for many fisheries worldwide. However, in most instances, those HCRs are not based on the explicit feedbacks between stock properties and economic considerations. This ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
A persistent debate in population ecology concerns the relative importance of environmental stochasticity and density dependence in determining variability in adult year-class strength, which contributes to future reproduction ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2015)
The catalytic residues in carbohydrate esterase enzyme families constitute a highly conserved triad: serine, histidine and aspartic acid. This catalytic triad is generally located in a very sharp turn of the protein backbone ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Mice lacking glycosylated lysosomal membrane protein (Glmp gt/gt mice) have liver fibrosis as the predominant phenotype due to chronic liver injury. The Glmp gt/gt mice grow and reproduce at the same rate as ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The Gauss-peak spectra (GPS) method represents individual pigment spectra as weighted sums of Gaussian functions, and uses these to model absorbance spectra of phytoplankton pigment mixtures. We here present several ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Eusociality is widely considered to evolve through kin selection, where the reproductive success of an individual’s close relative is favored at the expense of its own. High genetic relatedness ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The six transmembrane protein of prostate 2 (STAMP2) is an androgen‐regulated gene whose mRNA expression is increased in prostate cancer (PCa). Here, we show that STAMP2 protein expression is increased in human PCa compared ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
Thermophiles are extremophiles that grow optimally at temperatures >45 °C. To survive and maintain function of their biological molecules, they have a suite of characteristics not found in organisms that grow at moderate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background: Recent large-scale undertakings such as ENCODE and Roadmap Epigenomics have generated experimental data mapped to the human reference genome (as genomic tracks) representing a variety of functional elements ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Advances in whole genome sequencing strategies have provided the opportunity for genomic and comparative genomic analysis of a vast variety of organisms. The analysis results are highly dependent on the quality ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Understanding the factors that shape the evolution of gene expression is a central goal in biology, but the molecular mechanisms behind this remain controversial. A related major goal is ascertaining how such factors may ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
We have previously shown that aberrant promoter methylation of ZNF331 is a potential biomarker for colorectal cancer detection with high sensitivity (71%) and specificity (98%). This finding was recently confirmed by others, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a ...
(Doctoral thesis / Doktoravhandling, 2021)
Nanoparticles are small particles in the nanometer size range, undetectable by the human eye. Nowadays nanoparticles are investigated as carriers of therapeutic drugs to increase treatment effect and minimize side effects ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The toxicity resulting from exposure to oil droplets in marine fish embryos and larvae is still subject for debate. The most detailed studies have investigated the effects of water-dissolved components of crude oil in water ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
The Benthic Invertebrates of Icelandic Waters programme (BIOICE) was conducted between 1991 and 2004, for the purpose of gathering specimens within the Icelandic Exclusive Economic Zone (59° 58′N – 69° 35‘N and 30° 52’W – ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Large interannual fluctuations in the numbers of offspring joining a teleost population are common, yet factors affecting offspring production, a key driver of fish population size and demography, are often poorly understood. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The idea of a bioactive surface coating that enhances bone healing and bone growth is a strong focus of on-going research for bone implant materials. Enamel matrix derivate (EMD) is well documented to support bone regeneration ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Recent studies suggest that previous estimates of mesopelagic biomasses are severely biased, with the new, higher estimates underlining the need to unveil behaviourally mediated coupling between shallow and deep ocean ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Eculizumab is a humanized IgG2/4 chimeric anti-complement C5 antibody used to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) or atypical hemolytic uremic syndrome. The aim of this study was to evaluate whether ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Objective
Earlier studies documenting the effect of candidate genes on recovery have seldom taken into consideration the impact of emotional distress. Thus, we aimed to assess the modifying effect of emotional ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Gelatinous organisms apparently play a central role in deep pelagic ecosystems, but lack of observational methodologies has restricted information on their behaviour. We made acoustic records of diel migrating jellyfish ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Bergmann’s rule proposes that animals in cold habitats will be larger than those in warm habitats. This prediction has been tested thoroughly at the intraspecific level, but few studies have ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Natural stochasticity can pose challenges in managing the quality of the environment, or hinder understanding of the system structure. It is problematic because unfavourable stochastic events cancel management efforts and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Understanding responses of marine species to temperature variability is essential to predict impacts of future climate change in the oceans. Most ectotherms are expected to adjust their behavior to avoid extreme temperatures ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Many cellular proteins are methylated on lysine residues and this has been most intensively studied for histone proteins. Lysine methylations on non-histone proteins are also frequent, but in most cases the functional ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Zoonoses are increasingly recognized as an important burden on global public health in the 21st century. High-resolution, long-term field studies are critical for assessing both the baseline and future risk scenarios in a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Prediction of year-class strength is a critical challenge for fisheries managers. Theoretically, predictions of recruitment should be better when they are based on estimates of cohort size taken close to the age of recruitment ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2013)
Differential change in the phenology of predators and prey is a potentially important climate-mediated mechanism influencing populations. The match-mismatch hypothesis describes the effect of predator-prey population ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system. ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Rab7a, a small GTPase of the Rab family, is localized to late endosomes and controls late endocytic trafficking. The discovery of several Rab7a interacting proteins revealed that Rab7a function is closely connected to ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Divergence-time estimation based on molecular phylogenies and the fossil record has provided insights into fundamental questions of evolutionary biology. In Bayesian node dating, phylogenies are commonly time calibrated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Large herbivores gain nutritional benefits from following the sequential flush of newly emergent, high-quality forage along environmental gradients in the landscape, termed green wave surfing. Which landscape characteristics ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Supplemental feeding for ungulates is a widespread practice in many human-dominated landscapes across Europe and North America, mainly intended to seasonally support populations. Surprisingly, little consideration was given ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Warming-induced range shifts along elevational and latitudinal gradients have been observed in several species from various taxa. The mobility and behavioral plasticity of large endothermic mammals, however, complicate the ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
In the extracellular environment, the enzyme transglutaminase 2 (TG2) is involved in cell–matrix interactions through association with the extracellular matrix protein, fibronectin (FN). The 45 kDa gelatin-binding domain ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Studying herbal products derived from local and traditional knowledge and their value chains is one of the main challenges in ethnopharmacology. The majority of these products have a long history of use, but non-harmonized ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Increased concentrations of dissolved organic carbon (DOC), often labelled “browning”, is a current trend in northern, particularly boreal, freshwaters. The browning has been attributed to the recent reduction in sulphate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Population growth is affected by several factors such as climate, species interaction and harvesting pressure. However, additional complexity can arise if fishing increases the sensitivity to environmental variability. To ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Mutations in the N-myc downstream-regulated gene 1 (NDRG1) can cause degenerative polyneuropathy in humans, dogs, and rodents. In humans, this motor and sensory neuropathy is known as Charcot-Marie-Tooth ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Prostate cancer (PCa) is the most common non-cutaneous cancer in men. The androgen receptor (AR), a ligand-activated transcription factor, constitutes the main drug target for advanced cases of the disease. However, a ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)
Cryptic species could represent a substantial fraction of biodiversity. However, inconsistent definitions and taxonomic treatment of cryptic species prevent informed estimates of their contribution to biodiversity and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Current evidence of phenological responses to recent climate change is substantially biased towards northern hemisphere temperate regions. Given regional differences in climate change, shifts in phenology will not be uniform ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Computers are now essential in all branches of science, but most researchers are never taught the equivalent of basic lab skills for research computing. As a result, data can get lost, analyses can take much longer than ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Understanding the drivers (internal and external) that determine the productivity of marine ecosystems is challenging. For example, the correct estimate of recruitment is essential to estimate fish stock abundance. In this ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
A number of lysine-specific methyltransferases (KMTs) are responsible for the post-translational modification of cellular proteins on lysine residues. Most KMTs typically recognize specific motifs in unstructured, short ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Increased availability of genome assemblies for non-model organisms has resulted in invaluable biological and genomic insight into numerous vertebrates, including teleosts. Sequencing of the ...
The Effect on Mutated Tau Expression in Higher Visual Areas on Visual Discrimination Learning Restricted Access
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Ameloblastin (AMBN), an important component of the self-assembled enamel extra cellular matrix, contains several in silico predicted phosphorylation sites. However, to what extent these sites actually are phosphorylated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Shiga toxins consist of an A-moiety and five B-moieties able to bind the neutral glycosphingolipid globotriaosylceramide (Gb3) on the cell surface. To intoxicate cells efficiently, the toxin A-moiety has to be cleaved by ...
(Doctoral thesis / Doktoravhandling, 2018)
Over the past ten years the massive use of genomic and transcriptomic technologies has revealed groundbreaking information about the genetic drivers of cancer in general. The knowledge of these drivers is not only fundamental ...
(Doctoral thesis / Doktoravhandling, 2021)
Plague is a disease of rodents and is transmitted through their fleas. Humans are only occasionally infected. Direct human-to-human transmission through droplets happens rarely. The low plague activity in humans nowadays ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The neonatal crystallizable fragment receptor (FcRn) is responsible for maintaining the long half-life and high levels of the two most abundant circulating proteins, albumin and IgG. In the latter case, the protective ...