Browsing Institutt for biovitenskap by Title

Now showing items 1-20 of 1197

  • 1H, 13C, 15N backbone assignment of the human heat-labile enterotoxin B-pentamer and chemical shift mapping of neolactotetraose binding 
    Hatlem, Daniel; Heggelund, Julie Elisabeth; Burschowsky, Daniel; Krengel, Ute; Kristiansen, Per Eugen (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    The major virulence factor of enterotoxigenic Escherichia coli is the heat-labile enterotoxin (LT), an AB5 toxin closely related to the cholera toxin. LT consists of six subunits, the catalytically active A-subunit and ...
  • 454 Pyrosequencing to Describe Microbial Eukaryotic Community Composition, Diversity and Relative Abundance: A Test for Marine Haptophytes 
    Egge, Elianne Sirnæs; Bittner, Lucie; Andersen, Tom; Audic, Stéphane; de Vargas, Colomban; Edvardsen, Bente (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Next generation sequencing of ribosomal DNA is increasingly used to assess the diversity and structure of microbial communities. Here we test the ability of 454 pyrosequencing to detect the number of species present, and ...
  • 4D nucleome modeling 
    Paulsen, Jonas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The intrinsic dynamic nature of chromosomes is emerging as a fundamental component in regulating DNA transcription, replication, and damage-repair among other nuclear functions. With this increased awareness, reinforced ...
  • 5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication 
    Prikrylova, Terezia; Robertson, Julia; Ferrucci, Francesca; Konorska, Dorota Joanna; Aanes, Håvard; Manaf, Adeel; Zhang, Beibei; Vågbø, Cathrine Broberg; Kusnierczyk, Anna; Gilljam, Karin Margaretha; Løvkvam-Køster, Caroline; Otterlei, Marit; Dahl, John Arne; Enserink, Jorrit; Klungland, Arne; Robertson, Adam Brian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    In most mammalian cells, DNA replication occurs once, and only once between cell divisions. Replication initiation is a highly regulated process with redundant mechanisms that prevent errant initiation events. In lower ...
  • A 15-million-year-long record of phenotypic evolution in the heavily calcified coccolithophore Helicosphaera and its biogeochemical implications 
    Supraha, Luka; Henderiks, Jorijntje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    The biogeochemical impact of coccolithophores is defined not only by their overall abundance in the oceans but also by wide ranges in physiological traits such as cell size, degree of calcification and carbon production ...
  • A Bayesian Binomial Regression Model with Latent Gaussian Processes for Modelling DNA Methylation 
    Hubin, Aliaksandr; Storvik, Geir Olve; Grini, Paul Eivind; Butenko, Melinka Alonso (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Epigenetic observations are represented by the total number of reads from a given pool of cells and the number of methylated reads, making it reasonable to model this data by a binomial distribution. There are numerous ...
  • A brain and a head for a different habitat: Size variation in four morphs of Arctic charr (Salvelinus alpinus (L.)) in a deep oligotrophic lake 
    Tamayo, Ana-Maria Peris; Devineau, Olivier; Præbel, Kim; Kahilainen, Kimmo Kalevi; Østbye, Kjartan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Adaptive radiation is the diversification of species to different ecological niches and has repeatedly occurred in different salmonid fish of postglacial lakes. In Lake Tinnsjøen, one of the largest and deepest lakes in ...
  • A classification framework for Bacillus anthracis defined by global genomic structure 
    Bruce, Spencer A; Schiraldi, Nicholas J; Kamath, Pauline L.; Easterday, William Ryan; Turner, Wendy C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Bacillus anthracis , the causative agent of anthrax, is a considerable global health threat affecting wildlife, livestock, and the general public. In this study, whole‐genome sequence analysis of over 350 B. anthracis ...
  • “A cleaner break”: Genetic divergence between geographic groups and sympatric phenotypes revealed in ballan wrasse (Labrus bergylta) 
    Seljestad, Gaute; Sanchez, Maria Quintela; Faust, Ellika; Halvorsen, Kim Aleksander Tallaksen; Besnier, Francois; Jansson, Eeva; Dahle, Geir; Knutsen, Halvor; André, Carl; Folkvord, Arild; Glover, Kevin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Capture and long-distance translocation of cleaner fish to control lice infestations on marine salmonid farms has the potential to influence wild populations via overexploitation in source regions, and introgression in ...
  • A computational model for gonadotropin releasing cells in the teleost fish medaka 
    Halnes, Geir; Tennøe, Simen; Haug, Trude; Einevoll, Gaute; Weltzien, Finn-Arne; Hodne, Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Pituitary endocrine cells fire action potentials (APs) to regulate their cytosolic Ca2+ concentration and hormone secretion rate. Depending on animal species, cell type, and biological conditions, pituitary APs are generated ...
  • A de novo transcriptome assembly for the bath sponge Spongia officinalis, adjusting for microsymbionts 
    Manousaki, Tereza; Koutsouveli, Vasiliki; Lagnel, Jacques; Kollias, Spyridon; Tsigenopoulos, Costas S; Arvanitidis, Christos; Magoulas, Antonios; Dounas, Costas; Dailianis, Thanos (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Objectives We report a transcriptome acquisition for the bath sponge Spongia officinalis, a non-model marine organism that hosts rich symbiotic microbial communities. To this end, a pipeline was developed to efficiently ...
  • A genome-skimmed phylogeny of a widespread bryozoan family, Adeonidae 
    Orr, Russell J S; Haugen, Marianne N; Berning, Björn; Bock, Philip; Cumming, Robyn L; Florence, Wayne K; Hirose, Masato; Di Martino, Emanuela; Ramsfjell, Mali H; Sannum, Maja M; Smith, Abigail M; Vieira, Leandro M; Waeschenbach, Andrea; Liow, Lee Hsiang (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Understanding the phylogenetic relationships among species is one of the main goals of systematic biology. Simultaneously, credible phylogenetic hypotheses are often the first requirement for ...
  • A genome-wide linkage map for the house sparrow (Passer domesticus) provides insights into the evolutionary history of the avian genome 
    Hagen, Ingerid Julie; Lien, Sigbjørn; Billing, Anna Maria; Elgvin, Tore Oldeide; Trier, Cassandra Nicole; Niskanen, Alina K.; Tarka, Maja; Slate, Jon; Sætre, Glenn-Peter; Jensen, Henrik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    The house sparrow is an important model species for studying physiological, ecological and evolutionary processes in wild populations. Here, we present a medium density, genome wide linkage map for house sparrow (Passer ...
  • A genomic and historical synthesis of plague in 18th century Eurasia 
    Guellil, Meriam; Kersten, Oliver; Namouchi, Amine; Luciani, Stefania; Marota, Isolina; Arcini, Caroline; Iregren, Elisabeth; Lindemann, Robert; Warfvinge, Gunnar; Bakanidze, Leila; Bitadze, Lia; Rubini, Mauro; Zaio, Paola; Zaio, Monica; Neri, Damiano; Stenseth, Nils Christian; Bramanti, Barbara (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Plague continued to afflict Europe for more than five centuries after the Black Death. Yet, by the 17th century, the dynamics of plague had changed, leading to its slow decline in Western Europe over the subsequent 200 y, ...
  • A high-quality assembly of the nine-spined stickleback (Pungitius pungitius) genome 
    Varadharajan, Srinidhi; Rastas, Pasi; Löytynoja, Ari; Matschiner, Michael; Calboli, Federico C. F.; Guo, Baocheng; Nederbragt, Alexander Johan; Jakobsen, Kjetill Sigurd; Merilä, Juha (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The Gasterosteidae fish family hosts several species that are important models for eco-evolutionary, genetic and genomic research. In particular, a wealth of genetic and genomic data has been generated for the three-spined ...
  • A New Look at the Functional Organization of the Golgi Ribbon 
    Saraste, Jaakko; Prydz, Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    A characteristic feature of vertebrate cells is a Golgi ribbon consisting of multiple cisternal stacks connected into a single-copy organelle next to the centrosome. Despite numerous studies, the mechanisms that link the ...
  • A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes. 
    Lode, Heidrun Elisabeth; Gjølberg, TT; Foss, Stian; Sivertsen, Magne S.; Brustugun, Jørgen; Andersson, Yvonne; Jørstad, Øystein Kalsnes; Moe, Morten Carstens; Andersen, Jan Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Intravitreal injections of antibody-based biologics targeting vascular endothelial growth factor (VEGF) are highly effective and have markedly decreased the risk of visual impairment associated with prevalent retinal ...
  • A novel ultra high-throughput 16S rRNA gene amplicon sequencing library preparation method for the Illumina HiSeq platform 
    de Muinck, Eric J; Trosvik, Pål; Gilfillan, Gregor D; Hov, Johannes R; Sundaram, Arvind Y M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Advances in sequencing technologies and bioinformatics have made the analysis of microbial communities almost routine. Nonetheless, the need remains to improve on the techniques used for gathering ...
  • A Research-Inspired Biochemistry Laboratory Module - Combining Expression, Purification, Crystallization, Structure-Solving, and Characterization of a Flavodoxin-like Protein 
    Hammerstad, Marta; Kjendseth, Åsmund Røhr; Hersleth, Hans-Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Many laboratory courses consist of short and seemingly unconnected individual laboratory exercises. To increase the course consistency, relevance, and student engagement, we have developed a research‐inspired and project‐based ...
  • A risk assessment of the effects of mercury on Baltic Sea, Greater North Sea and North Atlantic wildlife, fish and bivalves 
    Dietz, Rune; Fort, Jérôme; Sonne, Christian; Albert, Céline; Bustnes, Jan Ove; Christensen, Thomas Kjær; Ciesielski, Tomasz Maciej; Danielsen, Jóhannis; Dastnai, Sam; Eens, Marcel; Erikstad, Kjell E; Galatius, Anders; Garbus, Svend-Erik; Gilg, Oliver; Hanssen, Sveinn Are; Helander, Björn; Helberg, Morten; Jaspers, Veerle; Jenssen, Bjørn Munro; Jónsson, Jón Einar; Kauhala, Kaarina; Kolbeinsson, Yann; Kyhn, Line A.; Labansen, Aili Lage; Larsen, Martin M.; Lindstrøm, Ulf; Reiertsen, Tone Kristin; Rigét, Frank F.; Roos, Anna; Strand, Jakob; Strøm, Hallvard; Søndergaard, Jens; Sun, Jiachen; Teilmann, Jonas; Therkildsen, Ole Roland; Thórarinsson, Thorkell Lindberg; Tjørnløv, Rune Skjold; Wilson, Simon; Eulaers, Igor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    A wide range of species, including marine mammals, seabirds, birds of prey, fish and bivalves, were investigated for potential population health risks resulting from contemporary (post 2000) mercury (Hg) exposure, using ...