Browsing Institutt for biovitenskap by Title
Now showing items 1-20 of 668
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)The major virulence factor of enterotoxigenic Escherichia coli is the heat-labile enterotoxin (LT), an AB5 toxin closely related to the cholera toxin. LT consists of six subunits, the catalytically active A-subunit and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Next generation sequencing of ribosomal DNA is increasingly used to assess the diversity and structure of microbial communities. Here we test the ability of 454 pyrosequencing to detect the number of species present, and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Advances in sequencing technologies and bioinformatics have made the analysis of microbial communities almost routine. Nonetheless, the need remains to improve on the techniques used for gathering ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background Multigenic diseases are often associated with protein complexes or interactions involved in the same pathway. We wanted to estimate to what extent this is true given a consolidated protein ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Colored dissolved organic matter (CDOM) absorbs a substantial fraction of photosynthetically active radiation (PAR) in boreal lakes. However, few studies have systematically estimated how this light absorption influences ...
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(Doctoral thesis / Doktoravhandling, 2018)The last few years have seen the arrival of new effective cancer therapies which is directed at the immune system rather than the cancer cells directly. One type of cancer immunotherapies is the so-called checkpoint ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)The multifunctional enzyme transglutaminase 2 (TG2) is the target of autoantibodies in the gluten-sensitive enteropathy celiac disease. In addition, the enzyme is responsible for deamidation of gluten peptides, which are ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)How genomic selection enables species to adapt to divergent environments is a fundamental question in ecology and evolution. We investigated the genomic signatures of local adaptation in Atlantic cod (Gadus morhua L.) along ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Theoretical models suggest that sympatric speciation along environmental gradients might be common in nature. Here we present the first data-based model of evolutionary diversification along a continuous environmental ...
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(Master thesis / Masteroppgave, 2016)
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The adaptor protein ARA55 and the nuclear kinase HIPK1 assist c-Myb in recruiting p300 to chromatin (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)LIM-domain proteins, containing multiple cysteine-rich zinc finger-like motifs, have been shown to play diverse roles in several cellular processes. A common theme is that they mediate important protein-protein interactions ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Comparative genomics of non-model organisms has resurrected whole genome duplication (WGD) from being viewed as a somewhat obscure process that happens in plants to a primary driver of eukaryotic diversification. The shadow ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)In migratory birds, mistimed arrival might have negative consequences for individual fitness, causing population declines. This may happen if arrival time is not synchronized with breeding time, especially when earlier ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Mice lacking glycosylated lysosomal membrane protein (Glmp gt/gt mice) have liver fibrosis as the predominant phenotype due to chronic liver injury. The Glmp gt/gt mice grow and reproduce at the same rate as ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)We used a comparative approach investigating commercially fished species with contrasting life histories and trophic positions in an Arcto-boreal system, the Barents Sea. Our objective was to address the ecological ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)Faithful chromosome segregation during mitosis relies on a proofreading mechanism that monitors proper kinetochore-microtubule attachments. The spindle assembly checkpoint (SAC) is based on the concerted action of numerous ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Studies on the consequences of ocean acidification for the marine ecosystem have revealed behavioural changes in coral reef fishes exposed to sustained near-future CO2 levels. The changes have been linked to altered function ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background The first Atlantic cod (Gadus morhua) genome assembly published in 2011 was one of the early genome assemblies exclusively based on high-throughput 454 pyrosequencing. Since then, rapid advances ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Bergmann’s rule proposes that animals in cold habitats will be larger than those in warm habitats. This prediction has been tested thoroughly at the intraspecific level, but few studies have ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background The Tarim Basin in western China, known for its amazingly well-preserved mummies, has been for thousands of years an important crossroad between the eastern and western parts of Eurasia. Despite ...