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Now showing items 1-100 of 2104
(Doctoral thesis / Doktoravhandling, 2024)
The Atlantic cod possesses a unique immune system, with an evolutionary loss of key genes crucial for antibody responses to conventional vaccines and combating infectious diseases in other vertebrates. This work found an ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Many pathogens and parasites can infect multiple host species, and the competence of different hosts as pathogen reservoirs is key to understanding their epidemiology. Small mammals are important ...
(Doctoral thesis / Doktoravhandling, 2024)
Characterizing the genomes of living organisms increasingly involves extensive use of computational tools for data processing and analysis. During my PhD, I have developed and utilized computational tools to improve our ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
The present study examined how climate changes may impact the concentrations of lipophilic organochlorines (OCs) in the blood of fasting High Arctic common eiders (Somateria mollissima) during incubation. Polychlorinated ...
(Doctoral thesis / Doktoravhandling, 2024)
The addition of a methyl group (CH3) to proteins, also known as protein methylation, is mediated by specialized enzymes named methyltransferases. One such enzyme is METTL13, which specifically trimethylates glycine 2 (G2me3) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
Objectives
We aimed to discover CpG sites with differential DNA methylation in peripheral blood leukocytes associated with body mass index (BMI) in pregnancy and gestational weight gain (GWG) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
The secretion of extracellular vesicles (EVs) is a common process in Gram-negative bacteria and can be exploited for biotechnological applications. EVs pose a self-adjuvanting, non-replicative vaccine platform, where ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Chronic wasting disease (CWD) is well known among cervids in North America. Nevertheless, management faced different types and degrees of uncertainty when CWD was first detected in reindeer Rangifer tarandus in Nordfjella, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
1. The state of sea trout in 1251 Norwegian watercourses was assessed based on a scoring system for human pressures, abundance data, and local knowledge. 2. Over 16,000 km of rivers and lakes were available to sea trout ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Molecular phylogenetics has revolutionized the taxonomy of crustose lichens and revealed an extensive amount of cryptic diversity. Resolving the relationships between genera in the crustose lichen family Tephromelataceae ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Aquaculture is the fastest-growing food sector worldwide but faces sustainability challenges that need to be addressed in many ways, including genetic enhancement. Atlantic cod has re-emerged as an aquaculture species and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Antimicrobial resistance is a major threat to human health and must be approached from a One Health perspective. Use of antimicrobials in animal husbandry can lead to dissemination and persistence of resistance in human ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Eusociality is widely considered to evolve through kin selection, where the reproductive success of an individual’s close relative is favored at the expense of its own. High genetic relatedness ...
The Effect on Mutated Tau Expression in Higher Visual Areas on Visual Discrimination Learning Restricted Access
(Master thesis / Masteroppgave, 2023)
(Doctoral thesis / Doktoravhandling, 2023)
Research on persistent organic pollutants (POPs) in tropical regions is scarce, with most efforts concentrated in the Global North. This disparity is concerning as new contaminants are being synthesized and old contaminants ...
Perturbations of perineuronal nets in the medial prefrontal cortex during learning of a visual discrimination task Restricted Access
(Master thesis / Masteroppgave, 2023)
(Doctoral thesis / Doktoravhandling, 2023)
In the future, pesticide transport and exposure in aquatic environments are expected to be altered by land-use and climate changes. These changes may lead to higher exposure concentrations and changes in agricultural ...
(Doctoral thesis / Doktoravhandling, 2023)
Pharmaceuticals are an important part of human pollution. Their use has been linked to several well-known wildlife crises, such as a population collapse of vultures in India and Pakistan, or the feminisation of fish ...
(Doctoral thesis / Doktoravhandling, 2023)
This is a thesis about the Atlantic herring – a small, unassuming silver fish that holds a special place in the hearts and history of many northern Europeans. Having been fished for thousands of years in the north Atlantic, ...
(Doctoral thesis / Doktoravhandling, 2023)
This thesis sums up several approaches on how the threespine stickleback are handling salinity changes, both over long time periods, through population genetic and morphometric analysis, and over shorter time periods, by ...
(Doctoral thesis / Doktoravhandling, 2023)
The study explores the molecular basis of severe mental disorders like schizophrenia and bipolar disorder and emphasizes the role of computational simulations in advancing their treatment. The dissertation presents two ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Arctic cod biomass are predicted. In most Arctic seas, the relative abundance of Arctic cod within the fish community will likely fluctuate in accordance with cold and warm periods. A reduced abundance of Arctic cod will ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Unravelling evolution-by-environment interactions on the gut microbiome is particularly relevant considering the unprecedented level of human-driven disruption of the ecological and evolutionary trajectories of species. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Genetically encoded Ca 2+ indicators (GECIs) are widely used to measure neural activity. Here, we explore the use of systemically administered PHP.eB AAVs for brain-wide expression of GECIs and compare the expression ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Although wild ungulate populations are heavily monitored throughout Europe, we understand little of how parasites affect population dynamics, and there is no systematic, long-term monitoring of ...
(Doctoral thesis / Doktoravhandling, 2023)
The harbour porpoise is one of the most common toothed whales in European waters, with a population of more than 600,000 individuals. Despite their numbers, porpoises are severely threatened by commercial fisheries – they ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Electronic waste is a source of both legacy and emerging flame retardants to the environment, especially in regions where sufficient waste handling systems are lacking. In the present study, we quantified the occurrence ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Healthy insect populations are vital for maintaining natural ecosystems and essential to global food security. The ongoing dramatic loss of insect species and biomass is thus a global cause for concern, with much focus on ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The three-dimensional organization of chromatin plays a crucial role in gene regulation and cellular processes like deoxyribonucleic acid (DNA) transcription, replication and repair. Hi-C and related techniques provide ...
(Doctoral thesis / Doktoravhandling, 2023)
This thesis explores the ecological transitions and evolutionary genomics of the dry rot fungus Serpula lacrymans and related species within the Serpulaceae family. Phylogenetics, evolutionary genomic approaches, as well ...
Blood Parasites, Fitness and MHC in the Bluethroat (Luscinia svecica) Restricted Access
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract The reproductive success of marine ectotherms is especially vulnerable in warming oceans due to alterations in adult physiology, as well as embryonic and larval survival prospects. These vital responses may, ...
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Cleaner fish are commonly used as a control measure against salmon lice infestations in salmonid farms. Lumpfish (Cyclopterus lumpus) is the most common cleaner fish species used in Norwegian farms. However, little is known ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
α-helical coiled-coils are ubiquitous protein structures in all living organisms. For decades, modified coiled-coils sequences have been used in biotechnology, vaccine development, and biochemical research to induce protein ...
(Doctoral thesis / Doktoravhandling, 2023)
The proteins in all living organism are composed of 20 primary amino acids. These can be modified by a variety of chemical modifications. One of the most important ones is methylation, which can occur on some of the amino ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Microbial interactions are fundamental for Earth’s ecosystem functioning and biogeochemical cycling. Nevertheless, they are challenging to identify and remain barely known. Omics-based censuses ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Repetitive DNA make up a considerable fraction of most eukaryotic genomes. In fish, transposable element (TE) activity has coincided with rapid species diversification. Here, we annotated the repetitive content in 100 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Cell immobilization is an important technique for efficiently utilizing whole-cell biocatalysts. We previously invented a method for bacterial cell immobilization using AtaA, a trimeric autotransporter adhesin from the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Persistent organic pollutants (POPs), including brominated flame retardants (BFRs), perfluoroalkyl substances (PFAS) and metals, can accumulate in marine mammals and be transferred to offspring. In this study, we analyzed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The management of infectious wildlife diseases often involves tackling pathogens that infect multiple host species. Chronic wasting disease (CWD) is a prion disease that can infect most cervid species. CWD was detected in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Glacial cycles play important roles in determining the phylogeographic structure of terrestrial species, however, relatively little is known about their impacts on the distribution of marine biota. This study ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The field of ancient DNA (aDNA) typically uses between 50 and 200 mg of minimum input weight of bone material for the extraction of DNA from archaeological remains. While laboratory and analysis techniques have focused on ...
(Doctoral thesis / Doktoravhandling, 2023)
Seabird populations worldwide have been declining dramatically over the last decades as a result of a range of environmental and anthropogenic stressors. Nevertheless, management of threatened seabirds is arguably hampered ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract After stone tools, bone tools are the most abundant artefact type in the Early Pleistocene archaeological record. That said, they are still relatively scarce, which limits our understanding of the behaviours that ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Previous bibliometric studies in scientific researchers from developed countries generally support that sharing efforts during research enhances productivity and impact and suggest these effects ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Innovative point-of-care (PoC) diagnostic platforms are desirable to surpass the deficiencies of conventional laboratory diagnostic methods for bacterial infections and to tackle the growing antimicrobial resistance crisis. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
1. Surveillance of wildlife diseases poses considerable logistical challenges compared to that of humans or livestock. Citizen science can enable broader coverage, but building an efficient disease monitoring system that ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Lyme borreliosis, the most common vector‐borne disease in Europe and North America, is attracting growing concern due to its expanding geographic range. The growth in incidence and geographic spread is largely ...
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
COVID-19 lockdowns in early 2020 reduced human mobility, providing an opportunity to disentangle its effects on animals from those of landscape modifications. Using GPS data, we compared movements and road avoidance of ...
Investigation of the effect of MED8 sumoylation on carboxy-terminal domain of RPB1 Restricted Access
(Master thesis / Masteroppgave, 2023)
Posttranslational modifications by the Small Ubiquitin-like Modifier (SUMO) in a dynamic and reversible process that plays a crucial role in biology by modulating protein structure, function, and dynamics. Numerous in vitro ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The decrease in Arctic sea-ice extent and thickness as a result of global warming will impact the timing, duration, magnitude and composition of phytoplankton production with cascading effects on Arctic marine food-webs ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Traditional strict separation of fungi into ecological niches as mutualist, parasite or saprotroph is increasingly called into question. Sequences of assumed saprotrophs have been amplified from plant root interiors, and ...
(Master thesis / Masteroppgave, 2023)
The spurdog (Squalus acanthias) is a common shark in the Northeast Atlantic. Through time, this species has been heavily exploited by fisheries which resulted in a gradually declining stock biomass. This led to the ...
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy ...
(Master thesis / Masteroppgave, 2023)
Knockout of NTHL1 DNA Glycosylase affects the Mitochondrial Transcriptome, DNA copy number and shows Tolerance to Parkinsonism-Inducing Drugs in Human Cells Restricted Access
(Master thesis / Masteroppgave, 2023)
Using target capture and next generation sequencing to resolve the phylogeny of the genus Crinum L. with emphasis on tropical African species Restricted Access
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Climate change related alterations in the Arctic have influences on the marine ecosystems, in particular on phytoplankton bloom dynamics. Since phytoplankton blooms are the main provider of carbon sources to the microbial ...
Long Term Effects of COVID-19 in Adolescents Exploring the Pathophysiology and Psychosocial Factors of Long COVID Restricted Access
(Master thesis / Masteroppgave, 2023)
Long COVID may be defined as a “post-COVID-19 condition that occurs in individuals with a history of probable or confirmed SARS-CoV-2 infection, usually 3 months from the onset, with symptoms that last for at least 2 months ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Bacteria of the Borrelia burgdorferi sensu lato (s.l.) complex can cause Lyme borreliosis. Different B. burgdorferi s.l. genospecies vary in their host and vector associations and human pathogenicity ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Near-shore areas face multiple stressors, effects of climate change, coastal construction and contamination. Although capping the seabed in these areas with mineral masses can reduce the impact of legacy contaminants in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Although bacterial thioredoxin reductase-like ferredoxin/flavodoxin NAD(P)+ oxidoreductases (FNRs) are similar in terms of primary sequences and structures, they participate in diverse biological processes by catalyzing a ...
O-linked protein glycosylation in Neisseria gonorrhoeae: Glycan diversity and cross-protective immune responses after meningococcal OMV vaccination Restricted Access
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
1. Quantifying the diet composition of apex marine predators such as killer whales (Orcinus orca) is critical to assessing their food web impacts. Yet, with few exceptions, the feeding ecology of these apex predators remains ...
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Climate change has a profound impact on species distribution and abundance globally, as well as local diversity which affects ecosystem functioning. Particularly, the changes of population distribution and abundance may ...
(Master thesis / Masteroppgave, 2023)
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
The ShK toxin from Stichodactyla helianthus has established the therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin families in Actiniarians remain uncharacterised. ...
Treatment effect of paclitaxel and carboplatin in resistant breast cancer cells and use of MALDI-TOF-MSI for protein detection in mouse xenograft tissue Restricted Access
(Master thesis / Masteroppgave, 2023)
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
We present a numerical approach to magnetic optical rotation based on real-time time-dependent electronic-structure theory. Not relying on perturbation expansions in the magnetic-field strength, the formulation allows us ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Phenotypic plasticity of metabolism and growth are essential for adaptation to new environmental conditions, such as those experienced during domestication. Epigenetic regulation plays a key role in this process but the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Semiconducting polymer nanoparticles (SPNs) are explored for applications in cancer theranostics because of their high absorption coefficients, photostability, and biocompatibility. However, SPNs are susceptible ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The actin cytoskeleton is tightly controlled by RhoGTPases, actin binding-proteins and nucleation-promoting factors to perform fundamental cellular functions. We have previously shown that ERK3, an atypical MAPK, controls ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Brown algae (Phaeophyceae) are habitat‐forming species in coastal ecosystems and include kelp forests and seaweed beds that support a wide diversity of marine life. Host‐associated microbial communities are an ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aurora B, together with IN-box, the C-terminal part of INCENP, forms an enzymatic complex that ensures faithful cell division. The [Aurora B/IN-box] complex is activated by autophosphorylation in the Aurora B activation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Gap junctions are specialized regions of the plasma membrane containing clusters of channels that provide for the diffusion of ions and small molecules between adjacent cells. A fundamental role of gap junctions is to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The diatom Pseudo-nitzschia H. Peragallo is perhaps the most intensively researched genus of marine pennate diatoms, with respect to species diversity, life history strategies, toxigenicity, and biogeographical distribution. ...
Assessment of inflammatory and cytotoxic effects of inhaled nickel nanoparticles using an advanced alveolar cell culture model Restricted Access
(Master thesis / Masteroppgave, 2023)
Exposure of nickel (Ni) particles has been linked to inflammatory responses in the human lung. The size of the particle has been shown to often correlate with the reactivity, entry and deposition of the particle in the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
An accurate method to estimate the age of a stain or the time since deposition (TsD) would represent an important tool in police investigations for evaluating the true relevance of a stain. In this study, two laboratories ...
(Doctoral thesis / Doktoravhandling, 2023)
Evolution has brought to life an immense diversity of forms, lifestyles and species in the fungi. Yet our knowledge about how this diversity has been generated remains sparse. I have taken a closer look at evolution in a ...
Phylogenetic studies and species delimitation in the genus Drimiopsis in East Africa Restricted Access
(Master thesis / Masteroppgave, 2023)
This project contributes to the knowledge of the phylogeny and morphology of Drimiopsis, with special emphasis on the species D. maculata, D. botryoides and D. sp. A. The latter is a provisional name used in a previous ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The aims were to characterize the content of elements and polycyclic aromatic hydrocarbons (PAHs) in size-separated particulate matter (PM) sampled in a road tunnel, estimate the contribution of PAHs to the toxic potential, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Parallel evolution provides strong evidence of adaptation by natural selection due to local environmental variation. Yet, the chronology, and mode of the process of parallel evolution remains debated. Here, we ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Individual heterozygosity may influence the expression of fitness‐related traits, via genome‐wide or local genetic effects. Earlier studies have shown negative relationships between heterozygosity and sperm variation, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
We present a novel function fitting method for approximating the propagation of the time-dependent electric dipole moment from real-time electronic structure calculations. Real-time calculations of the electronic absorption ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The crucian carp ( Carassius carassius ) can survive complete oxygen depletion (anoxia) for several months at low temperatures, making it an excellent model for studying molecular adaptations to anoxia. Still, little is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Liver sinusoidal endothelial cells (LSECs) are fenestrated endothelial cells with a unique, high endocytic clearance capacity for blood-borne waste macromolecules and colloids. This LSEC scavenger function has been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The Barents Sea is one of the Polar regions where current climate and ecosystem change is most pronounced. Here we review the current state of knowledge of the physical, chemical and biological systems in the Barents Sea. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Current evolutionary psychological (EP) perspectives on filicide perpetration propose that it is an extreme behavioral manifestation of psychological mechanisms that evolved due to their function toward enabling ancestrally ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
From biofilms to whale pods, organisms across taxalive in groups, thereby accruing numerous diverse benefits of soci-ality. All social organisms, however, pay the inherent cost of in-creased resource competition. One expects ...
(Master thesis / Masteroppgave, 2023)
Breast cancer remains the most prevalent cancer in women globally, with increasing incidences despite improved survival rates, emphasizing the need for enhanced diagnostics and treatments. Its heterogeneity is in part ...
Functional characterization of FAM129A in breast cancer cells Restricted Access
(Master thesis / Masteroppgave, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Brown trout (Salmo truttaL. 1758) and Arctic charr [Salvelinus alpinus(L. 1758)] taggedwith acoustic transmitters migrated from fresh water to the sea mainly in May andJune, but with large individual variation in migration ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Climate change affects timing of reproduction in many bird species, but few studies have investigated its influence on annual reproductive output. Here, we assess changes in the annual production of young by female breeders ...
(Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2023)
Evolutionary quantitative genetics (EQG) emerged as a research paradigm in the 1980s based on operational tools for studying variation, inheritance, and selection in field and lab studies. In this chapter, I review the ...