Browsing Institutt for biovitenskap by Author "Xiao, Rourou"

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  • Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer 
    Xiao, Rourou; You, Lixin; Zhang, Li; Guo, Xichen; Guo, Ensong; Zhao, Faming; Yang, Bin; Li, Xi; Fu, Yu; Lu, Funian; Wang, Zizhuo; Liu, Chen; Peng, Wenju; Li, Wenting; Yang, Xiaohang; Dou, Yingyu; Liu, Jingbo; Wang, Wei; Qin, Tianyu; Cui, Yaoyuan; Zhang, Xiaoxiao; Li, Fuxia; Jin, Yang; Zeng, Qingping; Wang, Beibei; Mills, Gordon B.; Chen, Gang; Sheng, Xia; Sun, Chaoyang (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Targeting the G2/M checkpoint mediator WEE1 has been explored as a novel treatment strategy in ovarian cancer, but mechanisms underlying its efficacy and resistance remains to be understood. Here, it is demonstrated that ...