Browsing Institutt for biovitenskap by Author "Qiao, Shuo Wang"

Now showing items 1-3 of 3

  • Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease 
    Høydahl, Lene Støkken; Richter, Lisa Maria; Frick, Rahel; Snir, Omri; Gunnarsen, Kristin Støen; Landsverk, Ole J. B.; Iversen, Rasmus; Jeliazkov, Jeliazko R.; Gray, Jeffrey J.; Bergseng, Elin; Foss, Stian; Qiao, Shuo Wang; Lundin, Knut Erik Aslaksen; Jahnsen, Jørgen; Jahnsen, Frode Lars; Sandlie, Inger; Sollid, Ludvig Magne; Løset, Geir Åge (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background & Aims Development of celiac disease is believed to involve the transglutaminase-dependent response of CD4+ T cells toward deamidated gluten peptides in the intestinal mucosa of individuals with specific ...
  • TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage 
    Dahal-Koirala, Shiva; Risnes, Louise Fremgaard; Christophersen, Asbjørn; Sarna, Vikas Kumar; Lundin, Knut Erik Aslaksen; Sollid, Ludvig Magne; Qiao, Shuo Wang (Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)
    CD4+ T cells recognizing dietary gluten epitopes in the context of disease-associated human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 molecules are the key players in celiac disease pathogenesis. Here, we conducted a large-scale ...
  • A TCRα framework–centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions 
    Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Risnes, Louise Fremgaard; Dahal-Koirala, Shiva; Neumann, Ralf Stefan; Bergseng, Elin; Frigstad, Terje; Frick, Rahel; du Pré, Marie Fleur; Dalhus, Bjørn; Lundin, Knut Erik Aslaksen; Qiao, Shuo Wang; Sollid, Ludvig Magne; Sandlie, Inger; Løset, Geir Åge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Selection of biased T cell receptor (TCR) repertoires across individuals is seen in both infectious diseases and autoimmunity, but the underlying molecular basis leading to these shared repertoires remains unclear. Celiac ...