Browsing CRIStin høstingsarkiv by Title
Now showing items 7419-7438 of 31257
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)As findings on the neuropathological and behavioral components of Alzheimer’s disease (AD) continue to accrue, converging evidence suggests that macroscale brain functional disruptions may mediate their association. Recent ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Our aim in this conceptual article is to theoretically reimagine the concept of ‘healthy prisons’ in a way that more thoroughly grounds it in the everyday experiences of prisoners. Our point of departure is the observation ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2022)When major disruptions occur in a rail network, the infrastructure manager and train operating companies may be forced to stop trains until the normal status is recovered. A crucial aspect is to identify, for each train, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Gene expression is generally regulated by recruitment of transcription factors and RNA polymerase II (RNAP II) to specific sequences in the gene promoter region. The Integrator complex mediates processing of small nuclear ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Upregulation of surface expressed sialoglycans on tumor cells is one of the mechanisms which promote tumor growth and progression. Specifically, the interactions of sialic acids with sialic acid-binding immunoglobulin-like ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Specific guanine-rich sequence motifs in the human genome have considerable potential to form four-stranded structures known as G-quadruplexes or G4 DNA. The enrichment of these motifs in key chromosomal regions has suggested ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Ellerman bombs and UV bursts are transient brightenings that are ubiquitously observed in the lower atmospheres of active and emerging flux regions. As they are believed to pinpoint sites of magnetic reconnection in ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)This paper examines whether nonlinear and non-Gaussian features of earnings dynamics are caused by hours or hourly wages. Our findings from the Norwegian administrative and survey data are as follows: (i) Nonlinear mean ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Post‐stroke fatigue (PSF) is prevalent among stroke patients, but its mechanisms are poorly understood. Many patients with PSF experience cognitive difficulties, but studies aiming to identify cognitive correlates of PSF ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)In the extracellular environment, the enzyme transglutaminase 2 (TG2) is involved in cell–matrix interactions through association with the extracellular matrix protein, fibronectin (FN). The 45 kDa gelatin-binding domain ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Parkinson's disease and Alzheimer's disease show overlapping features both clinically and neuropathologically and elucidating shared mechanisms could have important implications for therapeutic strategies. Evidence for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Characterizing the role of different mutational effect sizes in the evolution of fitness-related traits has been a major goal in volutionary biology for a century. Such characterization in a diversity of systems, both model ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)The Ordovician was a time of drastic biological and geological change. Previous work has suggested that there was a dramatic increase in global diversity during this time, but also has indicated that regional dynamics and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Chronic lymphocytic leukemia (CLL) is known for its strong dependency on the tumor microenvironment. We found progranulin (GRN), a protein that has been linked to inflammation and cancer, to be upregulated in the serum of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic ...
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Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Transcription factors use a DNA‐binding domain to localize their action and a transactivation domain (tAD) to stimulate activation of the associated gene. Recent work has renewed interest in how tADs activate genes, which ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Albumin is the most abundant protein in blood and plays a pivotal role as a multitransporter of a wide range of molecules such as fatty acids, metabolites, hormones, and toxins. In addition, it binds a variety of drugs. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Third-generation cephalosporins are a class of β-lactam antibiotics that are often used for the treatment of human infections caused by Gram-negative bacteria, especially Escherichia coli. Worryingly, the incidence of human ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)In Norway, the use of quinolones in livestock populations is very low, and prophylactic use is prohibited. Despite this, quinolone-resistant Escherichia coli (QREC) isolates are present at low levels in several animal ...