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Now showing items 1-9 of 9
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Objectives. Estimate the effect of atorvastatin on muscular symptom intensity in coronary patients with subjective statin-associated muscle symptoms (SAMS) and to determine the association with blood levels of atorvastatin ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Aims
Objective methods to monitor statin adherence are needed. We have established a liquid chromatography–tandem mass spectrometry assay for quantification of atorvastatin and its metabolites in blood. This study aimed ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background:
Low adherence to statin therapy remains a public health concern associated with poor prognosis in cardiovascular disease patients. A feasible method for statin adherence monitoring in clinical practice has ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background:
Therapeutic drug monitoring of tacrolimus (Tac) is mandatory in solid organ transplant (SOT) recipients. Finger-prick microsampling is more flexible and tolerable during the therapeutic drug monitoring of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
A fast and reliable method based on two-channel liquid chromatography coupled to tandem mass spectrometry was developed and successfully validated for quantification of busulfan. The drug vehicle polyethylene glycol 400 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Tacrolimus and sirolimus are important immunosuppressive drugs used in human islet transplantation; however, they are linked to detrimental effects on islets and reduction of long-term graft function. Few studies investigate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Self‐perceived statin‐associated muscle symptoms (SAMS) are prevalent, but only a minority is drug‐dependent. Diagnostic biomarkers are not yet identified. The local statin exposure in skeletal muscle tissue may correlate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aims Finger‐prick sampling has emerged as an attractive tool for therapeutic drug monitoring and associated diagnostics. We aimed to validate the clinical performance of using two volumetric devices (Capitainer® qDBS and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background and aims Statin-associated muscle symptoms (SAMS) is a prevalent cause of statin discontinuation. It is challenging and time-consuming for clinicians to assess whether symptoms are caused by the statin or not, ...