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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Objectives. Estimate the effect of atorvastatin on muscular symptom intensity in coronary patients with subjective statin-associated muscle symptoms (SAMS) and to determine the association with blood levels of atorvastatin ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background:
Low adherence to statin therapy remains a public health concern associated with poor prognosis in cardiovascular disease patients. A feasible method for statin adherence monitoring in clinical practice has ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Aims
Objective methods to monitor statin adherence are needed. We have established a liquid chromatography–tandem mass spectrometry assay for quantification of atorvastatin and its metabolites in blood. This study aimed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Self‐perceived statin‐associated muscle symptoms (SAMS) are prevalent, but only a minority is drug‐dependent. Diagnostic biomarkers are not yet identified. The local statin exposure in skeletal muscle tissue may correlate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background and aims Statin-associated muscle symptoms (SAMS) is a prevalent cause of statin discontinuation. It is challenging and time-consuming for clinicians to assess whether symptoms are caused by the statin or not, ...