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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Determination of proteins in complex biological matrices has massive attention and is exploited in many different scientific disciplines. Routinely, proteins are determined using antibody based immuno-metric assays. Although ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Immunocapture-based bottom-up LC–MS is a promising technique for the quantification of low abundant proteins. Magnetic immunocapture beads provide efficient enrichment from complex samples through the highly specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The aim of the present study was to develop a LC-MS/MS-based proteomic analysis method of urinary exosomal proteins that has the potential to discover disease biomarkers. In short, urinary exosomes from healthy subjects ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Robust biomarker quantification is essential for the accurate diagnosis of diseases and is of great value in cancer management. In this paper, an innovative diagnostic platform is presented which provides automated molecularly ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Molecularly imprinted polymers (MIPs) have been used as useful sorbents in solid-phase extraction for a wide range of molecules and sample matrices. Their unique selectivity can be fine-tuned in the imprinting process and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
A concept integrating sampling and protein digestion is introduced here combining fast and simple fabrication by wax printing on filter paper with trypsin immobilized polymer beads. The paper reactors showed promising ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The use of antibodies in “bottom-up “LC-MS workflows to determine low abundant biological active proteins in complex human samples has increased in recent years: immuno-capture analysis combines the workflow of conventional ...
The utility of molecularly imprinted polymers for mass spectrometric protein and proteomics analysis
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Selective and efficient sample clean-up is important in mass spectrometric protein- and proteomics analyses from biological matrices. Molecularly imprinted polymers (MIPs), polymers prepared to have tailor-made cavities ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Abstract The modification of an easily available resource like paper to circumvent expensive or intensive sample pretreatment could be the answer to sample analysis in resource-poor regions. Therefore, a novel on-paper ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
The purpose of this study was to develop a smart proteolysis sampler based on commercially available VAMS® tips employing Volumetric Absorptive Microsampling. In this proof-of-concept paper we show that covalently bound ...