Browsing Farmasøytisk institutt by Title
Now showing items 271-290 of 1934
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(Master thesis / Masteroppgave, 2017)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2002)Background Previous studies have shown that several agents that stimulate heptahelical G-protein coupled receptors activate the extracellular signal regulated kinases ERK1 (p44mapk) and ERK2 (p42mapk) in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)We recently introduced transformato, an open-source Python package for the automated setup of large-scale calculations of relative solvation and binding free energy differences. Here, we extend the capabilities of transformato ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)The extracellular biofilm matrix often contains a network of amyloid fibers which, in the human opportunistic pathogen Bacillus cereus , includes the two homologous proteins TasA and CalY. We show here, in the closely ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Purpose The purpose of the study is to identify and explore risk factors of serious adverse drug events (SADE) and SADE-related admissions in acutely hospitalized multimorbid older adults and assess whether these could ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)A positive inotropic responsiveness to serotonin, mediated by 5-HT4 and 5-HT2A receptors, appears in the ventricle of rats with post-infarction congestive heart failure (HF) and pressure overload-induced hypertrophy. A ...
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(Master thesis / Masteroppgave, 2010)Menneskekroppen har gjennom evolusjon utviklet genetisk programmerte metoder for å vedlikeholde cellepopulasjonen og opprettholde optimal organfunksjon. Apoptose er en form for programmert celledød som har en essensiell ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)The dynamics of marine populations are usually forced by biotic and abiotic factors occurring at different intensity levels and time scales. Deriving the time frame within which each factor has a causal influence is important ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)In Bacillus subtilis, motility genes are expressed in a hierarchical pattern – governed by the σD transcription factor and other proteins such as the EpsE molecular clutch and SlrA/SlrR regulator proteins. In contrast, ...
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(Master thesis / Hovedoppgave, 2006)ABSTRACT Cervical cancer is one of the major causes of gynecological death worldwide. The degree of cancer progression of is categorized into different stages. Therapy is given depending on the stage of the cancer. ...
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(Master thesis / Masteroppgave, 2011)Mitokondrier spiller en viktig rolle i nevronal skade og celledød. Ulike subpopulasjoner av mitokondrier antas å ha ulike egenskaper og påvirkning på disse prosessene. Ved nevronal celledød eller celleskade er glutamat ...
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(Master thesis / Hovedoppgave, 2007)SAMMENDRAG Celledød deles ofte inn i nekrose og apoptose. Apoptose er en velregulert celledødsprosess involvert i mange viktige funksjoner, blant annet utviklingen av nervesystemet. Ubalanse i forholdet mellom apoptosestimulerende ...
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(Doctoral thesis / Doktoravhandling, 2021)The bacterium Bacillus cereus is increasingly recognized as a major source of food-borne disease, as well as other severe infections. Biofilms are a common multicellular mode of growth, where bacteria can be protected ...
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(Master thesis / Masteroppgave, 2013)Legumain er en lysosomal endopeptidase som normalt er uttrykt i mange humane vev. Studier har imidlertid vist at uttrykket av legumain er oppregulert i kreftsvulster, og at legumain kan være involvert i metastasering og ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background: Vascular pathology is a common feature in patients with advanced Alzheimer’s disease, with cerebral amyloid angiopathy (CAA) and microvascular changes commonly observed at autopsies and in genetic mouse models. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Objectives: Pregnancy may cause changes in drug disposition, dose requirements and clinical response. For lithium, changes in disposition during pregnancy have so far been explored in a single-dose study on 4 participants ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background: Some women continue smoking during pregnancy despite the extensive information available on the dangers smoking poses to their fetus. This study aimed to examine the prevalence and determinants of smoking before ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)The inulin-type fructan was obtained by DEAE anion exchange chromatography from C. pilosula Nannf. var. modesta (Nannf.) L. T. Shen, after optimized extract condition, which was established by response surface methodology, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Vaccine development against extracellular bacteria has been important for the sustainability of the aquaculture industry. In contrast, infections with intracellular pathogens remain largely an unresolved problem. Francisella ...
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(Master thesis / Masteroppgave, 2016)Cancer is one of the leading causes of death worldwide, and anticancer treatments are also known to cause side effects that can affect life quality of the patients severely. Novel drug delivery systems (DDS), e.g., polymeric ...