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(Doctoral thesis / Doktoravhandling, 2020)
Legumain is an enzyme present in most cells but its dysregulation is associated with several diseases. During stem cell differentiation, legumain stimulates fat cell and inhibits osteoblast differentiation. This thesis ...
(Doctoral thesis / Doktoravhandling, 2021)
CACNA1C and CACNA1D are voltage-gated calcium channel genes that have been repeatedly associated with psychiatric disorders by various genomic studies. These genes are involved in gene expression regulation, neurotransmitter ...
(Doctoral thesis / Doktoravhandling, 2020)
Main research findings
In the field of bioanalysis, drug molecules and endogenous compounds can be determined and quantified from biological samples such as blood and urine. However, the complexity of such biological ...
Effects of feeding mice with different Plin genotypes a methionine-choline-deficient (MCD) diet - a model of nonalcoholic steatohepatitis (NASH) disease. Restricted Access
(Master thesis / Masteroppgave, 2020)
(Doctoral thesis / Doktoravhandling, 2020)
Livelong immunosuppressive treatment is needed after renal transplantation. Tacrolimus has been the cornerstone in most transplant centers. Its narrow therapeutic window and large inter- and intra-individual variability ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
We explored glucometabolic and renal function after engraftment in all 159 consecutive patients with type 1 diabetes who received pancreas transplantation alone (PTA, n = 80) or simultaneous pancreas and kidney transplantation ...
(Master thesis / Masteroppgave, 2020)
Circadisk påvirkning på farmakokinetikken til mykofenolat og mykofenolatglukuronid i nyretransplanterte pasienter Restricted Access
(Master thesis / Masteroppgave, 2020)
Bakgrunn: Etter en nyretransplantasjon er immunsupprimerende behandling helt nødvendig, og mykofenolatmofetil (MMF) inngår som en del av behandlingen og doseres morgen og kveld. Mykofenolat (MPA) glukuronideres til ...
(Doctoral thesis / Doktoravhandling, 2020)
Extracellular vesicles are small round bodies secreted from the membranes of most living cells, including bacteria. The bacterial vesicles contain many of the same components as the mother bacteria and play numerous roles ...
(Master thesis / Masteroppgave, 2020)