Browsing Det odontologiske fakultet by Author "Corthay, Alexandre"

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  • How do CD4+ T cells detect and eliminate tumor cells that either lack or express MHC class II molecules? 
    Haabeth, Ole Audun; Tveita, Anders; Fauskanger, Marte Hotvedt; Schjesvold, Fredrik Hellem; Lorvik, Kristina Berg; Hofgaard, Peter Olaf; Omholt, Hilde; Munthe, Ludvig Andre; Dembic, Zlatko; Corthay, Alexandre; Bogen, Bjarne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    CD4+ T cells contribute to tumor eradication, even in the absence of CD8+ T cells. Cytotoxic CD4+ T cells can directly kill MHC class II positive tumor cells. More surprisingly, CD4+ T cells can indirectly eliminate tumor ...