Browsing Det odontologiske fakultet by Author "Bogen, Bjarne"

Now showing items 1-2 of 2

  • B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells 
    Huszthy, Peter Csaba; Gopalakrishnan, Ramakrishna Prabhu; Jacobsen, Johanne Tracey; Haabeth, Ole Audun; Løset, Geir Åge; Braathen, Ranveig; Schenck, Karl; Tveita, Anders Aune; Munthe, Ludvig Andre; Bogen, Bjarne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The B cell receptors (BCRs) for antigen express variable (V) regions that are enormously diverse, thus serving as markers on individual B cells. V region-derived idiotypic (Id) peptides can be displayed as pId:MHCII complexes ...
  • How do CD4+ T cells detect and eliminate tumor cells that either lack or express MHC class II molecules? 
    Haabeth, Ole Audun; Tveita, Anders; Fauskanger, Marte Hotvedt; Schjesvold, Fredrik Hellem; Lorvik, Kristina Berg; Hofgaard, Peter Olaf; Omholt, Hilde; Munthe, Ludvig Andre; Dembic, Zlatko; Corthay, Alexandre; Bogen, Bjarne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    CD4+ T cells contribute to tumor eradication, even in the absence of CD8+ T cells. Cytotoxic CD4+ T cells can directly kill MHC class II positive tumor cells. More surprisingly, CD4+ T cells can indirectly eliminate tumor ...