Browsing Institutt for medisinske basalfag by Title

Now showing items 1281-1300 of 3153

  • GABA, but not bestrophin-1, is localized in astroglial processes in the mouse hippocampus and the cerebellum 
    Ormel, Lasse; Lauritzen, Knut Husø; Schreiber, Rainer; Kunzelmann, Karl; Gundersen, Vidar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    GABA is proposed to act as a gliotransmitter in the brain. Differences in GABA release from astroglia are thought to underlie differences in tonic inhibition between the cerebellum and the CA1 hippocampus. Here we used ...
  • GAK and PRKCD are positive regulators of PRKN-independent mitophagy 
    Munson, Michael J.; Mathai, Benan J.; Ng, Matthew Yoke Wui; Trachsel-Moncho, Laura; de la Ballina, Laura R.; Schultz, Sebastian W.; Aman, Yahyah; Lystad, Alf H.; Singh, Sakshi; Singh, Sachin; Wesche, Jørgen; Fang, Evandro F.; Simonsen, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract The mechanisms involved in programmed or damage-induced removal of mitochondria by mitophagy remains elusive. Here, we have screened for regulators of PRKN-independent mitophagy using an siRNA library targeting ...
  • GAK and PRKCD kinases regulate basal mitophagy. 
    Munson, Michael Joseph; Mathai, Benan John; Ng, Matthew; Trachsel-Moncho, Laura; de la Ballina, Laura R; Simonsen, Anne Gjøen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    The removal of mitochondria in a programmed or stress-induced manner is essential for maintaining cellular homeostasis. To date, much research has focused upon stress-induced mitophagy that is largely regulated by the E3 ...
  • Gap junction-dependent coordination of intercellular calcium signalling in the developing appendicularian tunicate Oikopleura dioica 
    Mikhaleva, Yana; Tolstenkov, Oleg; Glover, Joel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    We characterized spontaneous Ca2+ signals in Oikopleura dioica embryos from pre-fertilization to gastrula stages following injection of GCaMP6 mRNA into unfertilized eggs. The unfertilized egg exhibited regular, transient ...
  • Gaps and discontinuation of statin treatment in Norway: potential for optimizing management of lipid lowering drugs 
    Engebretsen, Ingrid; Munkhaugen, John; Bugge, Christoffer; Halvorsen, Sigrun; Ødegaard, Kristina Malene; Støvring, Henrik; Kristiansen, Ivar Sønbø (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Aims In clinical practice many patients do not reach the recommended treatment targets for LDL-cholesterol levels. We aimed to examine treatment patterns and adherence for patients on lipid lowering drugs in Norway ...
  • Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels 
    Hofsø, Dag; Birkeland, Kåre I; Holst, Jens J; Bollerslev, Jens; Sandbu, Rune; Røislien, Jo; Hjelmesæth, Jøran (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Gastric bypass surgery seems to have an effect on glucose metabolism beyond what is mediated through weight reduction. The magnitude of this effect on fasting and post-challenge glucose levels ...
  • Gastric bypass surgery is associated with reduced subclinical myocardial injury and greater activation of the cardiac natriuretic peptide system than lifestyle intervention 
    Aakre, Kristin Moberg; Omland, Torbjørn; Nordstrand, Njord; Gjevestad, Espen Svendsen; Holven, Kirsten Bjørklund; Lyngbakken, Magnus; Hjelmesæth, Jøran (Journal article / Tidsskriftartikkel / SubmittedVersion, 2020)
    Aims Morbid obesity is a risk factor for cardiovascular disease. The relative effects of Roux-en-Y gastric bypass surgery (GBS) and intensive lifestyle intervention (ILI) on subclinical myocardial injury, the activity ...
  • Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery 
    Aukan, Marthe Isaksen; Skårvold, Silje; Brandsæter, Ingrid Øfsti; Rehfeld, Jens Frederik; Holst, Jens Juul; Nymo, Siren; Coutinho, Silvia; Martins, Catia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Objective The aim of this study was to compare changes in gastrointestinal hormones and appetite ratings after a similar weight loss induced by a very low‐energy diet alone or in combination with sleeve gastrectomy ...
  • Gastrointestinal symptoms and quality of life in relation to malnutrition after gastrectomy for gastric cancerRestricted Access 
    Ullerud, Åslaug Asgeirsdatter (Master thesis / Masteroppgave, 2018)
  • Gastrostomi hos barn - En prospektiv studie av vekst og ernæringsoppfølging, sett i lys av dagens behandlingstilbud for barn med spise- og ernæringsvanskerRestricted Access 
    Birketvedt, Kjersti (Master thesis / Masteroppgave, 2016)
    Bakgrunn: Spise- og ernæringsvansker hos barn er utbredt, spesielt i enkelte diagnosegrupper. For noen barn er vanskene så komplekse eller langvarige at de har behov for gastrostomi. Bruken av gastrostomi er økende, både ...
  • GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study 
    Rongve, Arvid; Witoelar, Aree; Ruiz, Agustín; Athanasiu, Lavinia; Abdelnour, Carla; Clarimon, Jordi; Heilmann-Heimbach, Stefanie; Hernández, Isabel; Moreno-Grau, Sonia; de Rojas, Itziar; Morenas-Rodríguez, Estrella; Fladby, Tormod; Sando, Sigrid Botne; Bråthen, Geir; Blanc, Frédéric; Bousiges, Olivier; Lemstra, Afina W.; van Steenoven, Inger; Londos, Elisabet; Almdahl, Ina Selseth; Pålhaugen, Lene; Eriksen, Jon Alm; Djurovic, Srdjan; Stordal, Eystein; Saltvedt, Ingvild; Ulstein, Ingun; Bettella, Francesco; Desikan, Rahul S.; Idland, Ane-Victoria; Toft, Mathias; Pihlstrøm, Lasse; Snaedal, Jon; Tárraga, Lluís; Boada, Mercè; Lleó, Alberto; Stefánsson, Hreinn; Stefánsson, Kári; Ramírez, Alfredo; Aarsland, Dag; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ...
  • Gender Differences in Associations between Biomechanical and Psychosocial Work Exposures and Age of Withdrawal from Paid Employment among Older Workers 
    Undem, Karina; Leinonen, Taina; Kristensen, Petter; Merkus, Suzanne; Hasting, Rachel Louise; Gran, Jon Michael; Mehlum, Ingrid Sivesind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background: Work exposures are known predictors of withdrawal from employment, but the associations between work exposures and withdrawal may vary with gender. This study evaluated gender differences in associations between ...
  • Gender differences in nutrition literacy levels among university students and employees: a descriptive study. 
    Svendsen, Karianne; Torheim, Liv Elin; Fjelberg, Vibeke; Sorprud, Anja; Narverud, Ingunn; Retterstøl, Kjetil; Bogsrud, Martin Prøven; Holven, Kirsten Bjørklund; Myhrstad, Mari; Telle-Hansen, Vibeke (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The impact of nutrition information on public health is partly determined by the population's level of nutrition literacy (NL), which involves functional NL (such as knowledge of dietary guidelines) and critical NL (such ...
  • Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain 
    Dervola, Kine S.; Johansen, Espen B.; Walaas, S. Ivar; Fonnum, Frode (Journal article / Tidsskriftartikkel / SubmittedVersion, 2015)
    Polychlorinated biphenyls (PCBs) are present as ortho- and non-ortho-substituted PCBs, with most of the ortho-substituted congeners being neurotoxic. The present study examined effects of the ortho-substituted PCB 153 on ...
  • Gender-specific mediators of the association between parental education and adiposity among adolescents: the HEIA study 
    Gebremariam, Mekdes Kebede; Arah, Onyebuchi A.; Bergh, Ingunn Holden; Andersen, Lene Frost; Ommundsen, Yngvar; Totland, Torunn Holm; Bjelland, Mona; Grydeland, May; Lien, Nanna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Identifying the mechanisms behind socioeconomic inequalities in adiposity among youth is vital for efforts aimed at combating these inequalities. The study explored whether a broad range of behavioral and familial factors ...
  • Gene exchange drives the ecological success of a multi-host bacterial pathogen 
    Richardson, Emily J; Bacigalupe, Rodrigo; Harrison, Ewan M; Weinert, Lucy A.; Lycett, Samantha; Vrieling, Manouk; Robb, Kirsty; Hoskisson, Paul A; Holden, Matthew T.G.; Feil, Edward J.; Paterson, Gavin K; Tong, Steven Y C; Shittu, Adebayo; van Wamel, Willem; Aanensen, David M.; Parkhill, Julian; Peacock, Sharon J.; Corander, Jukka; Holmes, Mark; Fitzgerald, J. Ross (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    The capacity for some pathogens to jump into different host-species populations is a major threat to public health and food security. Staphylococcus aureus is a multi-host bacterial pathogen responsible for important human ...
  • Gene expression analysis supports tumor threshold over 2.0 cm for T-category breast cancer 
    Solvang, Hiroko Kato; Frigessi, Arnoldo; Kaveh, Fatemeh; Riis, Margit; Luders, Torben; Bukholm, Ida Rashida Khan; Kristensen, Vessela N.; Andreassen, Bettina Kulle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Tumor size, as indicated by the T-category, is known as a strong prognostic indicator for breast cancer. It is common practice to distinguish the T1 and T2 groups at a tumor size of 2.0 cm. We investigated the 2.0-cm rule ...
  • Gene expression is differentially regulated in skeletal muscle and circulating immune cells in response to an acute bout of high-load strength exercise 
    Gjevestad, Gyrd O; Hamarsland, Håvard; Raastad, Truls; Ottestad, Inger; Christensen, Jacob J; Eckardt, Kristin; Drevon, Christian A; Biong, Anne S; Ulven, Stine M; Holven, Kirsten B (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background High-intensity exercise induces many metabolic responses. In is unknown whether the response in the peripheral blood mononuclear cells (PBMCs) reflects the response in skeletal muscle and whether ...
  • Gene expression profiles in preterm infants on continuous long-term oxygen therapy suggest reduced oxidative stress-dependent signaling during hypoxia 
    Kalikstad, Betty; Kultima, Hanna Goransson; Andersstuen, Terese; Klungland, Arne; Isaksson, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Preterm infants are susceptible to neonatal inflammatory/infective diseases requiring drug therapy. The present study hypothesized that mRNA expression in the blood may be modulated by signaling pathways during treatment. ...
  • Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features 
    Haakensen, Vilde D; Christian Lingjærde, Ole; Lüders, Torben; Riis, Margit; Prat, Aleix; Troester, Melissa A; Holmen, Marit M; Ole Frantzen, Jan; Romundstad, Linda; Navjord, Dina; Bukholm, Ida K; Johannesen, Tom B; Perou, Charles M; Ursin, Giske; Kristensen, Vessela N; Børresen-Dale, Anne-Lise; Helland, Åslaug (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Increased understanding of the variability in normal breast biology will enable us to identify mechanisms of breast cancer initiation and the origin of different subtypes, and to better predict ...