Browsing Institutt for medisinske basalfag by Title
Now showing items 1428-1447 of 3153
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background: Romania has had one of the highest rates of cervical cancer incidence and mortality in Europe for decades. Data on the high-risk human papillomavirus (hrHPV) prevalence within the Romanian population are crucial ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Macroautophagy/autophagy is a membrane trafficking and intracellular degradation process involving the formation of double-membrane autophagosomes and their ultimate fusion with lysosomes. Much is yet to be learned about ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)A fundamental question is how autophagosome formation is regulated. Here we show that the PX domain protein HS1BP3 is a negative regulator of autophagosome formation. HS1BP3 depletion increased the formation of LC3-positive ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Aquaporin-4 (AQP4), the predominant water channel in the brain, is expressed in astrocytes and ependymal cells. In rodents AQP4 is highly polarized to perivascular astrocytic endfeet and loss of AQP4 polarization is ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)As the European Flagship Human Brain Project (HBP) ends in September 2023, a meeting dedicated to the Partnering Projects (PPs), a collective of independent research groups that partnered with the HBP, was held on September ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract LRRK2-G2019S is one of the most common Parkinson’s disease (PD)-associated mutations and has been shown to alter microglial functionality. However, the impact of LRRK2-G2019S on transcriptional profile of human ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)MCL, Mincle and Dectin-2 are C-type lectin receptors expressed by subsets of myeloid cells, and their genes cluster together in the APLEC/Dectin-2 gene complex. We have previously shown that MCL and Mincle form a heterodimer ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background More than 14 % of Ugandan children are orphaned and many live in children’s homes. Ugandan authorities have targeted adolescent girls as a priority group for nutrition interventions as safeguarding ...
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Human Rights Dimensions of Food, Health and Care in Selected Children s Homes in Kampala, Uganda – Experiences of Female Adolescent Residents as Rights-holdersRestricted Access (Master thesis / Masteroppgave, 2014)Background: More than 14 percent of children in Uganda are orphaned, and many of them live in children s homes. Very little information exists regarding how these homes are operated and what the conditions in these homes ...
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(Master thesis / Masteroppgave, 2009)Summary A major health problem in South Africa is inadequate nutritional health among infants and young children which contributes to increased childhood morbidity and mortality. The health authorities in South Africa have ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Human telomerase reverse transcriptase (hTERT) remains suppressed in most normal somatic cells. Resulting erosion of telomeres leads eventually to replicative senescence. Reactivation of hTERT maintains telomeres and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)The stomach-derived hormone ghrelin motivates food search and stimulates food consumption, with highest plasma concentrations before a meal and lowest shortly after. However, ghrelin also appears to affect the value of ...
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(Master thesis / Masteroppgave, 2008)Hensikten med undersøkelsen var å kartlegge og vurdere hvilemetabolisme og næringsinntak til en gruppe barn og unge med spinal muskelatrofi (SMA) og en gruppe barn og unge med Duchenne muskeldystrofi (DMD). Vi hadde ingen ...
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(Master thesis / Masteroppgave, 2018)Innledning Et globalt engasjement for ernæring og ernæringstiltak kommer fra FN og WHO: i form av konkrete og ambisiøse målsetninger som tar sikte på å bedre helsesituasjonen hos verdens befolkning, og sørge for lik ...
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(Master thesis / Masteroppgave, 2023)Bakgrunn: Tidlig barndom regnes som en periode der vaner dannes og er dermed et viktig tidspunkt for forebygging av ikke-smittsomme sykdommer. Foreldrene har den viktigste rollen for påvirkning av barnas kostholdsvaner. ...
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(Master thesis / Hovedoppgave, 2007)Utbredelsen av diabetes øker i alle land man har data for og sykdommen er i ferd med å anta epidemiske dimensjoner. I Norge regner man med at ca 200 000 personer kan ha type 2-diabetes. Halvparten av disse vet ikke at de ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)With cAMP signaling having a profound inhibitory effect on DNA damage-induced apoptosis in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells, understanding how this signaling pathway affects the survival capacity ...
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(Master thesis / Masteroppgave, 2011)Goal: The aim of the current thesis was to study the effect of hyperglycemia (HG) on MMP secretion from human primary endothelial cells. Background: Diabetes Mellitus is characterized by abnormal high levels of glucose ...
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(Master thesis / Masteroppgave, 2011)Bakgrunn og formål: Diabetes mellitus er en type kroniske sykdommer kjennetegnet ved hyperglykemi. Forventet levealder hos personer med diabetes er økt, men sykdommen forårsaker alvorlige sekundære komplikasjoner. ...
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(Doctoral thesis / Doktoravhandling, 2018)Birth asphyxia can lead to hypoxic-ischaemic (HI) brain injury. A concomitant perinatal infection increases the risk of neurological sequelae. Hypothermia treatment (HT) is current standard treatment for birth asphyxia. ...