Browsing Institutt for molekylær biovitenskap by Author "Noordhuis, Paul"

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  • MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines 
    Ohnstad, Hege O; Paulsen, Erik B; Noordhuis, Paul; Berg, Marianne; Lothe, Ragnhild A; Vassilev, Lyubomir T; Myklebost, Ola (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches. The small-molecule MDM2 antagonist Nutlin-3a activates the p53 pathway and efficiently ...