Browsing Institutt for molekylær biovitenskap by Author "Meza-Zepeda, Leonardo A"

Now showing items 1-6 of 6

  • Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours 
    Kresse, Stine H; Szuhai, Karoly; Barragan-Polania, Ana H; Rydbeck, Halfdan; Cleton-Jansen, Anne-Marie; Myklebost, Ola; Meza-Zepeda, Leonardo A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Several high-density oligonucleotide microarray platforms are available for genome-wide single nucleotide polymorphism (SNP) detection and microarray-based comparative genomic hybridisation (array ...
  • GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data 
    Lyng, Heidi; Lando, Malin; Brøvig, Runar S; Svendsrud, Debbie H; Johansen, Morten; Galteland, Eivind; Brustugun, Odd T; Meza-Zepeda, Leonardo A; Myklebost, Ola; Kristensen, Gunnar B; Hovig, Eivind; Stokke, Trond (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)
    Absolute tumor DNA copy numbers can currently be achieved only on a single gene basis by using fluorescence in situ hybridization (FISH). We present GeneCount, a method for genome-wide calculation of absolute copy numbers ...
  • Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells 
    Henriksen, Jørn; Stabell, Marianne; Meza-Zepeda, Leonardo A; Lauvrak, Silje A; Kassem, Moustapha; Myklebost, Ola (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background The HMGA2 gene, coding for an architectural transcription factor involved in mesenchymal embryogenesis, is frequently deranged by translocation and/or amplification in mesenchymal tumours, generally ...
  • M-CGH: Analysing microarray-based CGH experiments 
    Wang, Junbai; Meza-Zepeda, Leonardo A; Kresse, Stine H; Myklebost, Ola (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)
    Background Microarray-based comparative genomic hybridisation (array CGH) is a technique by which variation in relative copy numbers between two genomes can be analysed by competitive hybridisation to DNA ...
  • Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH 
    Kresse, Stine H; Berner, Jeanne-Marie; Meza-Zepeda, Leonardo A; Gregory, Simon G; Kuo, Wen-Lin; Gray, Joe W; Forus, Anne; Myklebost, Ola (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
    Background Amplification of the q21-q23 region on chromosome 1 is frequently found in sarcomas and a variety of other solid tumours. Previous analyses of sarcomas have indicated the presence of at least ...
  • mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts 
    Kuijjer, Marieke L; Namløs, Heidi M; Hauben, Esther I; Machado, Isidro; Kresse, Stine H; Serra, Massimo; Llombart-Bosch, Antonio; Hogendoorn, Pancras C; Meza-Zepeda, Leonardo A; Myklebost, Ola; Cleton-Jansen, Anne-Marie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Conventional high-grade osteosarcoma is a primary malignant bone tumor, which is most prevalent in adolescence. Survival rates of osteosarcoma patients have not improved significantly in the last ...