Browsing Institutt for molekylær biovitenskap by Author "Berg, Marianne"

Now showing items 1-3 of 3

  • Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas 
    Ribeiro, Franclim R; Henrique, Rui; Hektoen, Merete; Berg, Marianne; Jerónimo, Carmen; Teixeira, Manuel R; Lothe, Ragnhild A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background In order to gain new insights into the molecular mechanisms involved in prostate cancer, we performed array-based comparative genomic hybridization (aCGH) on a series of 46 primary prostate ...
  • Hypermethylated MAL gene – a silent marker of early colon tumorigenesis 
    Lind, Guro E; Ahlquist, Terje; Kolberg, Matthias; Berg, Marianne; Eknæs, Mette; Alonso, Miguel A; Kallioniemi, Anne; Meling, Gunn I; Skotheim, Rolf I; Rognum, Torleiv O; Thiis-Evensen, Espen; Lothe, Ragnhild A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)
    Background Tumor-derived aberrantly methylated DNA might serve as diagnostic biomarkers for cancer, but so far, few such markers have been identified. The aim of the present study was to investigate the ...
  • MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines 
    Ohnstad, Hege O; Paulsen, Erik B; Noordhuis, Paul; Berg, Marianne; Lothe, Ragnhild A; Vassilev, Lyubomir T; Myklebost, Ola (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches. The small-molecule MDM2 antagonist Nutlin-3a activates the p53 pathway and efficiently ...