Abstract
The overall aim of this thesis is to explore how real-world evidence can be used to support priority setting and planning in the cancer care. The thesis includes four published papers in which data from Norwegian health registries are used to study management of cancer, resource use and costs. In Paper 1, health care costs are estimated to NOK 21 billion, while lost productivity and the value of lost health amount to NOK 28 and 180 billion, respectively. The results from Paper II indicate that the treatment costs are highest during the initial treatment phase and in the terminal phase. Paper III examines the use of anti-cancer drugs end-of-life and provide evidence that fewer patients receive such treatment in Norway compared with other countries. The analyses in Paper IV shows that most of the gender differences in treatment costs end-of-life can be explained by differences in the type of cancer, age, and place of death. The four included papers demonstrate in various ways how real-world evidence can support health economic analyzes, which can provide information to support efficient and fair distribution of resources.
List of papers
Paper 1. Bugge, Christoffer; Sæther, Erik Magnus; Brustugun, Odd & Kristiansen, Ivar Sønbø (2021). Societal cost of cancer in Norway –Results of taking a broader cost perspective. Health Policy. ISSN 0168-8510. doi: 10.1016/j.healthpol.2021.05.008. The article is included in the thesis. Also available at: https://doi.org/10.1016/j.healthpol.2021.05.008 |
Paper 2. Bugge, Christoffer; Brustugun, Odd Terje; Sæther, Erik Magnus & Kristiansen, Ivar Sønbø (2021). Phase- and gender-specific, lifetime, and future costs of cancer: A retrospective population-based registry study. Medicine. ISSN 0025-7974. 100(26), s 1- 8. doi: 10.1097/MD.0000000000026523. The article is included in the thesis. Also available at: https://doi.org/10.1097/MD.0000000000026523 |
Paper 3. Bugge, Christoffer; Kaasa, Stein; Sæther, Erik Magnus; Melberg, Hans Olav & Kristiansen, Ivar Sønbø. What are determinants of utilisation of pharmaceutical anti-cancer treatment during the last year of life in Norway? a retrospective registry study. BMJ Open 2021;:1–7. doi: bmjopen-2021-050564. The article is included in the thesis. Also available at: https://doi.org/bmjopen-2021-050564 |
Paper 4. Bugge, Christoffer; Sæther, Erik Magnus & Kristiansen, Ivar Sønbø (2021). Men receive more end-of-life cancer hospital treatment than women: fact or fiction? Acta Oncologica. 60(80). S 984-991, doi: 10.1080/0284186X.2021.1917000. The article is not available in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1080/0284186X.2021.1917000 |