dc.date.accessioned | 2021-01-05T19:11:56Z | |
dc.date.available | 2021-01-05T19:11:56Z | |
dc.date.created | 2020-12-10T09:53:06Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Braz-Silva, Paulo Ana, Mamana Romano, Camila Felix, Alvina Paula, Anderson Fereira, Noeli Buss, Lewis Tozetto-Mendoza, Tania Caixeta, Rafael Leal, Fabio E. Grespan, Regina Bizário, João Ferraz, Andrea Sapkota, Dipak Giannecchini, Simone To, Kelvin KW Doglio, Alain Mendes-Correa, Maria . Performance of at-home self-collected saliva and nasal-oropharyngeal swabs in the surveillance of COVID-19. Journal of Oral Microbiology. 2020 | |
dc.identifier.uri | http://hdl.handle.net/10852/81932 | |
dc.description.abstract | Background: SARS-CoV-2 quickly spreads in the worldwide population, imposing social restrictions to control the infection, being the massive testing another essential strategy to break the chain of transmission.
Aim: To compare the performance of at-home self-collected samples – saliva and combined nasal-oropharyngeal swabs (NOP) – for SARS-CoV-2 detection in a telemedicine platform for COVID-19 surveillance.
Material and methods: We analyzed 201 patients who met the criteria of suspected COVID-19. NOP sampling was combined (nostrils and oropharynx) and saliva collected using a cotton pad device. Detection of SARS-COV-2 was performed by using the Altona RealStar® SARS-CoV-2 RT-PCR Kit 1.0.
Results: There was an overall significant agreement (κ coefficient value of 0.58) between saliva and NOP. Considering results in either sample, 70 patients positive for SARS-CoV-2 were identified, with 52/70 being positive in NOP and 55/70 in saliva. This corresponds to sensitivities of 74.2% (95% CI; 63.7% to 83.1%) for NOP and 78.6% (95% CI; 67.6% to 86.6%) for saliva.
Conclusion: Our data show the feasibility of using at-home self-collected samples (especially saliva), as an adequate alternative for SARS-CoV-2 detection. This new approach of testing can be useful to develop strategies for COVID-19 surveillance and for guiding public health decisions. | |
dc.language | EN | |
dc.publisher | Co-Action Publishing | |
dc.rights | Attribution-NonCommercial 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.title | Performance of at-home self-collected saliva and nasal-oropharyngeal swabs in the surveillance of COVID-19 | |
dc.type | Journal article | |
dc.creator.author | Braz-Silva, Paulo | |
dc.creator.author | Ana, Mamana | |
dc.creator.author | Romano, Camila | |
dc.creator.author | Felix, Alvina | |
dc.creator.author | Paula, Anderson | |
dc.creator.author | Fereira, Noeli | |
dc.creator.author | Buss, Lewis | |
dc.creator.author | Tozetto-Mendoza, Tania | |
dc.creator.author | Caixeta, Rafael | |
dc.creator.author | Leal, Fabio E. | |
dc.creator.author | Grespan, Regina | |
dc.creator.author | Bizário, João | |
dc.creator.author | Ferraz, Andrea | |
dc.creator.author | Sapkota, Dipak | |
dc.creator.author | Giannecchini, Simone | |
dc.creator.author | To, Kelvin KW | |
dc.creator.author | Doglio, Alain | |
dc.creator.author | Mendes-Correa, Maria | |
cristin.unitcode | 185,16,15,0 | |
cristin.unitname | Institutt for oral biologi | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1858180 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal of Oral Microbiology&rft.volume=&rft.spage=&rft.date=2020 | |
dc.identifier.jtitle | Journal of Oral Microbiology | |
dc.identifier.volume | 13 | |
dc.identifier.issue | 1 | |
dc.identifier.doi | https://doi.org/10.1080/20002297.2020.1858002 | |
dc.identifier.urn | URN:NBN:no-84902 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 2000-2297 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/81932/2/Performance%2Bof%2Bat%2Bhome%2Bself%2Bcollected%2Bsaliva%2Band%2Bnasal%2Boropharyngeal%2Bswabs%2Bin%2Bthe%2Bsurveillance%2Bof%2BCOVID%2B19.pdf | |
dc.type.version | PublishedVersion | |
cristin.articleid | 1858002 | |