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Now showing items 31-40 of 65
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Individuals heterozygous for germline ATM mutations have been reported to have an increased risk for breast cancer but the role for ATM genetic variants for breast cancer risk has remained unclear. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
The glycogen synthase kinase 3 (GSK3)/SHAGGY-like kinases (GSKs) are non-receptor serine/threonine protein kinases that are involved in a variety of biological processes. In contrast to the two ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Gene expression profiling has been used to define molecular phenotypes of complex diseases such as breast cancer. The luminal A and basal-like subtypes have been repeatedly identified and validated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU) causes DNA damage, which in turn affects cell proliferation and survival. Two stable wild-type TP53 5-FU-resistant cell lines, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Hormone therapy, oral contraceptives, and tamoxifen increase the risk of thrombotic disease. These compounds also reduce plasma content of tissue factor pathway inhibitor-1 (TFPI), which is the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Exposure to ambient particulate matter has been associated with a number of adverse health effects. Particle characteristics such as size, surface area and chemistry seem to influence the negative ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
The aim of the study was to validate the Norwegian version of a self-administered 43-item questionnaire designed to assess quality of life in kidney transplant recipients, the End-Stage Renal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Age-related alterations in metabolism and excretion of medications increase the risk of adverse drug events in the elderly. Inappropriate polypharmacy and prescription practice entails increased ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Two main genes encoding the catalytic subunits Cα and Cβ of cyclic AMP dependent protein kinase (PKA) have been identified in all vertebrates examined. The murine, bovine and human Cβ genes encode ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
Holotranscobalamin, cobalamin-saturated transcobalamin, is the minor fraction of circulating cobalamin (vitamin B12), which is available for cellular uptake and hence is physiologically relevant. ...