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Compliance with recommended cancer patient pathway timeframes and choice of treatment differed by cancer type and place of residence among cancer patients in Norway in 2015–2016 
Nilssen, Yngvar; Brustugun, Odd T.; Eriksen, Morten T.; Guren, Marianne G.; Haug, Erik S.; Naume, Bjørn; Schlichting, Ellen; Møller, Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Cancer patient pathways (CPPs) were implemented in Norway to reduce unnecessary waiting times, regional variations, and to increase the predictability of cancer care for the patients. This study ...
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease 
Visser, Pieter J.; Reus, Lianne M.; Gobom, Johan; Jansen, Iris; Dicks, Ellen; van der Lee, Sven J.; Tsolaki, Magda; Verhey, Frans R. J.; Popp, Julius; Martinez-Lage, Pablo; Vandenberghe, Rik; Lleó, Alberto; Molinuevo, José L.; Engelborghs, Sebastiaan; Freund-Levi, Yvonne; Froelich, Lutz; Sleegers, Kristel; Dobricic, Valerija; Lovestone, Simon; Streffer, Johannes; Vos, Stephanie J. B.; Bos, Isabelle; Smit, August B.; Blennow, Kaj; Scheltens, Philip; Teunissen, Charlotte E.; Bertram, Lars; Zetterberg, Henrik; Tijms, Betty M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Increased total tau (t-tau) in cerebrospinal fluid (CSF) is a key characteristic of Alzheimer’s disease (AD) and is considered to result from neurodegeneration. T-tau levels, however, can be ...
Engaging with EPIO, a digital pain self-management program: a qualitative study 
Bostrøm, Katrine; Varsi, Cecilie; Eide, Hilde; Børøsund, Elin; Kristjansdottir, Ólöf B.; Schreurs, Karlein M. G.; Waxenberg, Lori B.; Weiss, Karen E.; Morrison, Eleshia J.; Nordang, Elise F.; Stubhaug, Audun; Nes, Lise S. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Chronic pain conditions entail significant personal and societal burdens and improved outreach of evidence-based pain self-management programs are needed. Digital cognitive-behavioral self-management ...
The value of a redesigned clinical course during COVID-19 pandemic: an explorative convergent mixed-methods study 
Egilsdottir, H. Ö.; Heyn, Lena G.; Brembo, Espen A.; Byermoen, Kirsten R.; Moen, Anne; Eide, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The COVID-19 lockdown in March 2020 had a significant consequence for nursing students worldwide including limited access to learning situations in clinical rotation. Therefore, this study aims ...
Characterizing and quantifying low-value diagnostic imaging internationally: a scoping review 
Kjelle, Elin; Andersen, Eivind R.; Krokeide, Arne M.; Soril, Lesley J. J.; van Bodegom-Vos, Leti; Clement, Fiona M.; Hofmann, Bjørn M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Inappropriate and wasteful use of health care resources is a common problem, constituting 10–34% of health services spending in the western world. Even though diagnostic imaging is vital for ...
One- and 2-year flare rates after treat-to-target and tight-control therapy of gout: results from the NOR-Gout study 
Uhlig, Till; Karoliussen, Lars F.; Sexton, Joe; Kvien, Tore K.; Haavardsholm, Espen A.; Perez-Ruiz, Fernando; Hammer, Hilde B. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Objectives To explore the frequency and predictors of flares over 2 years during a treat-to-target strategy with urate-lowering therapy (ULT) in patients with gout. ...
Experiences of shared decision making among patients with psychotic disorders in Norway: a qualitative study 
Haugom, Espen W.; Stensrud, Bjørn; Beston, Gro; Ruud, Torleif; Landheim, Anne S. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Shared decision making (SDM) is a process where the patient and the health professional collaborate to make decisions based on both the patient’s preferences and the best available evidence. ...
The experiences, needs and barriers of people with impairments related to usability and accessibility of digital health solutions, levels of involvement in the design process and strategies for participatory and universal design: a scoping review 
Henni, Silje H.; Maurud, Sigurd; Fuglerud, Kristin S.; Moen, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Objective Globally, the number of digital health solutions is increasing, but they are not always designed with access and utilisation for people with impairments in mind. Development efforts have often not ...
Stroke unit demand in Norway – present and future estimates 
Dahl, Fredrik A.; Barra, Mathias; Faiz, Kashif W.; Ihle-Hansen, Hege; Næss, Halvor; Rand, Kim; Rønning, Ole M.; Simonsen, Tone B.; Thommessen, Bente; Labberton, Angela S. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background All stroke patients should receive timely admission to a stroke unit (SU). Consequently, most patients with suspected strokes – including stroke mimics (SM) are admitted. The aim of this study ...
Use of assessment instruments in forensic evaluations of criminal responsibility in Norway 
Løvgren, Pia J.; Laake, Petter; Reitan, Solveig K.; Narud, Kjersti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Objectives Assessment instruments are often used to enhance quality and objectivity in therapeutic and legal settings. We aimed to explore the use of instruments in Norwegian reports of forensic evaluations ...
Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers 
Lemma, Roza B.; Fleischer, Thomas; Martinsen, Emily; Ledsaak, Marit; Kristensen, Vessela; Eskeland, Ragnhild; Gabrielsen, Odd S.; Mathelier, Anthony (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Methylation of cytosines on DNA is a prominent modification associated with gene expression regulation. Aberrant DNA methylation patterns have recurrently been linked to dysregulation of the regulatory program in cancer ...
Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms (TIME) in home care services: a cluster randomized feasibility trial 
Hoel, Kari-Anne; Lichtwarck, Bjørn; Væringstad, Anette; Feiring, Ingvild H.; Rokstad, Anne M. M.; Selbæk, Geir; Benth, Jūratė Š.; Bergh, Sverre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Behavioral and psychological symptoms of dementia (BPSD) occur frequently in people with dementia and can contribute to an increased need for help and a reduced quality of life, but also predict ...
Effect of aerobic exercise intensity on health-related quality of life in severe obesity: a randomized controlled trial 
Berge, Jarle; Hjelmesæth, Jøran; Kolotkin, Ronette L.; Støren, Øyvind; Bratland-Sanda, Solfrid; Hertel, Jens K.; Gjevestad, Espen; Småstuen, Milada C.; Helgerud, Jan; Bernklev, Tomm (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Aerobic exercise is an important part of obesity treatment and may improve health-related quality of life (HRQOL). The objective of this study was to compare the effect of two different exercise ...
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway 
Helland, Åslaug; Russnes, Hege G.; Fagereng, Gro L.; Al-Shibli, Khalid; Andersson, Yvonne; Berg, Thomas; Bjørge, Line; Blix, Egil; Bjerkehagen, Bodil; Brabrand, Sigmund; Cameron, Marte G.; Dalhaug, Astrid; Dietzel, Dalia; Dønnem, Tom; Enerly, Espen; Flobak, Åsmund; Fluge, Sverre; Gilje, Bjørnar; Gjertsen, Bjørn T.; Grønberg, Bjørn H.; Grønås, Kari; Guren, Tormod; Hamre, Hanne; Haug, Åse; Heinrich, Daniel; Hjortland, Geir O.; Hovig, Eivind; Hovland, Randi; Iversen, Ann-Charlotte; Janssen, Emiel; Kyte, Jon A.; von der Lippe Gythfeldt, Hedda; Lothe, Ragnhild; Lund, Jo-Åsmund; Meza-Zepeda, Leonardo; Munthe-Kaas, Monica C.; Nguyen, Olav T. D.; Niehusmann, Pitt; NilsenPuco, Hilde K.; Ree, Anne H.; Riste, Tonje B.; Semb, Karin; Steinskog, Eli S. S.; Stensvold, Andreas; Suhrke, Pål; Tennøe, Øyvind; Tjønnfjord, Geir E.; Vassbotn, Liv J.; Aas, Eline; Aasebø, Kristine; Tasken, Kjetil; Smeland, Sigbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old ...
The validity of self-reported number of teeth and edentulousness among Norwegian older adults, the HUNT Study 
Høvik, Hedda; Kolberg, Marit; Gjøra, Linda; Nymoen, Line C.; Skudutyte-Rysstad, Rasa; Hove, Lene H.; Sun, Yi-Qian; Fagerhaug, Tone N. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Number of teeth is an established indicator of oral health and is commonly self-reported in epidemiological studies due to the costly and labor-intensive nature of clinical examinations. Although ...
Association between total and leisure time physical activity and risk of myocardial infarction and stroke – a Swedish cohort study 
Hummel, Madeleine; Hantikainen, Essi; Adami, Hans-Olov; Ye, Weimin; Bellocco, Rino; Bonn, Stephanie E.; Lagerros, Ylva T. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Physical inactivity is a known risk factor for cardiovascular disease, but it is unclear if total and leisure time activity have different impact on the risk of myocardial infarction and stroke. ...
A preliminary simulation-based qualitative study of healthcare students’ experiences of interprofessional primary care scenarios 
Lunde, Lene; Moen, Anne; Jakobsen, Rune B.; Møller, Britta; Rosvold, Elin O.; Brænd, Anja M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Introducing interprofessional education (IPE) in healthcare curricula can prepare students for healthcare practices that have become increasingly complex. The use of simulation is promoted to ...
Sleep and energy drink consumption among Norwegian adolescents – a cross-sectional study 
Kaldenbach, Siri; Leonhardt, Marja; Lien, Lars; Bjærtnes, Asborg A.; Strand, Tor A.; Holten-Andersen, Mads N. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Adolescents are recommended to get 8–10 h of sleep at night, yet more than 80% fail to obtain this goal. Energy drink (ED) consumption has been linked to later bedtime in adolescents. Therefore, ...
Epidemiology of traumatic cervical spinal fractures in a general Norwegian population 
Utheim, Nils C.; Helseth, Eirik; Stroem, Mona; Rydning, Paal; Mejlænder-Evjensvold, Magnus; Glott, Thomas; Hoestmaelingen, Christina T.; Aarhus, Mads; Roenning, Paal A.; Linnerud, Hege (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background In Western countries, the typical cervical spine fracture (CS-Fx) patient has historically been a young male injured in a road traffic accident. Recent reports and daily clinical practice clearly ...
Gene expression of fibrinolytic markers in coronary thrombi 
Nordeng, Jostein; Solheim, Svein; Åkra, Sissel; Schandiz, Hossein; Hoffmann, Pavel; Roald, Borghild; Bendz, Bjørn; Arnesen, Harald; Helseth, Ragnhild; Seljeflot, Ingebjørg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The fibrinolytic system plays an important role in coronary artery atherothrombosis, and especially circulating plasminogen-activator inhibitor (PAI) type 1 (PAI-1) associates with increased ...
Association between statin use and physical performance in home-dwelling older patients receiving polypharmacy: cross-sectional study 
Veddeng, Sigbjørn; Madland, Håkon; Molden, Espen; Wyller, Torgeir B.; Romskaug, Rita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background In older patients with polypharmacy and multiple comorbidities, even low grades of statin-associated muscle symptoms may have clinical implications. The aim of this study was therefore to ...
Sugar-sweetened beverage tax implementation processes: results of a scoping review 
Forberger, Sarah; Reisch, Lucia; Meshkovska, Biljana; Lobczowska, Karolina; Scheller, Daniel A.; Wendt, Janine; Christianson, Lara; Frense, Jennifer; Steinacker, Jürgen M.; Luszczynska, Aleksandra; Zeeb, Hajo (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Taxing sugar-sweetened beverages (SSB) is seen as a win–win situation for governments. It is argued that SSB taxes are relatively easy to implement from a practical perspective compared to for example other nutrition ...
A new automated and putatively versatile synthesis of the PSMA-ligand derivative [18F]DCFPyL using the FASTlabTM synthesizer 
Hoareau, Raphaël; Bach-Gansmo, Tore; Cumming, Paul; Olberg, Dag E. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Noninvasive molecular imaging using peptides and biomolecules labelled with positron emitters has become important for detection of cancer and other diseases with PET (positron emission tomography). ...
Hospital physicians’ experiences and reflections on their work and role in relation to older patients’ pathways - a qualitative study in two Norwegian hospitals 
Leonardsen, Ann-Chatrin L.; Werner, Anne; Lurås, Hilde; Johannessen, Anne-Kari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Older patients are the most frequent users of initial hospital admissions and readmissions. Both hospital admission and discharge require communication and coordination between healthcare ...
Lifestyle predictors for inconsistent participation to fecal based colorectal cancer screening 
Knudsen, Markus D.; Kvaerner, Ane S.; Botteri, Edoardo; Holme, Øyvind; Hjartåker, Anette; Song, Mingyang; Thiis-Evensen, Espen; Randel, Kristin R.; Hoff, Geir; Berstad, Paula (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Consistent participation in colorectal cancer (CRC) screening with repeated fecal immunochemical test (FIT) is important for the success of the screening program. We investigated whether lifestyle ...
Covert therapeutic micro-processes in non-recovered eating disorders with childhood trauma: an interpersonal process recall study 
Olofsson, Malin E.; Vrabel, KariAnne R.; Hoffart, Asle; Oddli, Hanne W. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Method To uncover therapeutic micro-processes from the perspectives of eating disorder (ED) treatment non-responders with childhood trauma (CT) late effects, we explored in-session experiences of poor ...
Accessibility and interventions of crisis resolution teams: a multicenter study of team practices and team differences in Norway 
Ruud, Torleif; Holgersen, Katrine H.; Hasselberg, Nina; Siqveland, Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Components of crisis resolution teams’ (CRTs) practices have been defined in recommendations and a fidelity scale, and surveys have reported how team leaders describe CRT practices. However, ...
Long-term patterns of an interconnected core marine microbiota 
Krabberød, Anders K.; Deutschmann, Ina M.; Bjorbækmo, Marit F. M.; Balagué, Vanessa; Giner, Caterina R.; Ferrera, Isabel; Garcés, Esther; Massana, Ramon; Gasol, Josep M.; Logares, Ramiro (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Ocean microbes constitute ~ 70% of the marine biomass, are responsible for ~ 50% of the Earth’s primary production and are crucial for global biogeochemical cycles. Marine microbiotas include ...
Adaptive treatment allocation and selection in multi-arm clinical trials: a Bayesian perspective 
Arjas, Elja; Gasbarra, Dario (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Adaptive designs offer added flexibility in the execution of clinical trials, including the possibilities of allocating more patients to the treatments that turned out more successful, and early ...
“Psychometric properties of the Norwegian foot function index revised short form” 
Mørk, Marianne; Hoksrud, Aasne F.; Soberg, Helene L.; Zucknick, Manuela; Heide, Marte; Groven, Karen S.; Røe, Cecilie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Foot disorders affect up to one quarter of the adult population. Plantar fasciopathy is a common cause of foot pain associated with decreased activity level and quality of life. Patient-reported ...
Synthesizing evidence from clinical trials with dynamic interactive argument trees 
Sanchez-Graillet, Olivia; Witte, Christian; Grimm, Frank; Grautoff, Steffen; Ell, Basil; Cimiano, Philipp (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Evidence-based medicine propagates that medical/clinical decisions are made by taking into account high-quality evidence, most notably in the form of randomized clinical trials. Evidence-based ...
A qualitative study on promoting reablement among older people living at home in Norway: opportunities and constraints 
Ambugo, Eliva A.; Dar, Imran; Bikova, Mariya S.; Førland, Oddvar; Tjerbo, Trond (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Healthcare services that traditionally have been provided in long-term care institutions in Norway are increasingly being delivered at home to a growing population of older people with chronic ...
Breast cancer risks associated with missense variants in breast cancer susceptibility genes 
Dorling, Leila; Carvalho, Sara; Allen, Jamie; Parsons, Michael T.; Fortuno, Cristina; González-Neira, Anna; Heijl, Stephan M.; Adank, Muriel A.; Ahearn, Thomas U.; Andrulis, Irene L.; Auvinen, Päivi; Becher, Heiko; Beckmann, Matthias W.; Behrens, Sabine; Bermisheva, Marina; Bogdanova, Natalia V.; Bojesen, Stig E.; Bolla, Manjeet K.; Bremer, Michael; Briceno, Ignacio; Camp, Nicola J.; Campbell, Archie; Castelao, Jose E.; Chang-Claude, Jenny; Chanock, Stephen J.; Chenevix-Trench, Georgia; Collée, J. M.; Czene, Kamila; Dennis, Joe; Dörk, Thilo; Eriksson, Mikael; Evans, D. G.; Fasching, Peter A.; Figueroa, Jonine; Flyger, Henrik; Gabrielson, Marike; Gago-Dominguez, Manuela; García-Closas, Montserrat; Giles, Graham G.; Glendon, Gord; Guénel, Pascal; Gündert, Melanie; Hadjisavvas, Andreas; Hahnen, Eric; Hall, Per; Hamann, Ute; Harkness, Elaine F.; Hartman, Mikael; Hogervorst, Frans B. L.; Hollestelle, Antoinette; Hoppe, Reiner; Howell, Anthony; Jakubowska, Anna; Jung, Audrey; Khusnutdinova, Elza; Kim, Sung-Won; Ko, Yon-Dschun; Kristensen, Vessela N.; Lakeman, Inge M. M.; Li, Jingmei; Lindblom, Annika; Loizidou, Maria A.; Lophatananon, Artitaya; Lubiński, Jan; Luccarini, Craig; Madsen, Michael J.; Mannermaa, Arto; Manoochehri, Mehdi; Margolin, Sara; Mavroudis, Dimitrios; Milne, Roger L.; Mohd Taib, Nur A.; Muir, Kenneth; Nevanlinna, Heli; Newman, William G.; Oosterwijk, Jan C.; Park, Sue K.; Peterlongo, Paolo; Radice, Paolo; Saloustros, Emmanouil; Sawyer, Elinor J.; Schmutzler, Rita K.; Shah, Mitul; Sim, Xueling; Southey, Melissa C.; Surowy, Harald; Suvanto, Maija; Tomlinson, Ian; Torres, Diana; Truong, Thérèse; van Asperen, Christi J.; Waltes, Regina; Wang, Qin; Yang, Xiaohong R.; Pharoah, Paul D. P.; Schmidt, Marjanka K.; Benitez, Javier; Vroling, Bas; Dunning, Alison M.; Teo, Soo H.; Kvist, Anders; de la Hoya, Miguel; Devilee, Peter; Spurdle, Amanda B.; Vreeswijk, Maaike P. G.; Easton, Douglas F. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Protein truncating variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2 are associated with increased breast cancer risk, but risks associated with missense variants in these genes are uncertain. ...
Suicidal ideation in patients with mental illness and concurrent substance use: analyses of national census data in Norway 
Andersson, Helle W.; Lilleeng, Solfrid E.; Ruud, Torleif; Ose, Solveig O. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Suicidal ideation may signal potential risk for future suicidal behaviors and death. We examined the prevalence of recent suicidal ideation in patients with mental illness and concurrent substance ...
Barriers and facilitators to implementation of direct fruit and vegetables provision interventions in kindergartens and schools: a qualitative systematic review applying the consolidated framework for implementation research (CFIR) 
Meshkovska, Biljana; Scheller, Daniel A.; Wendt, Janine; Jilani, Hannah; Scheidmeir, Marie; Stratil, Jan M.; Lien, Nanna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Although children’s intake of fruit and vegetables has seen a recent rise, almost half of adolescents do not eat even one piece of fruit or vegetables per day. One way to address this problem ...
The effect of sexual abuse and dissociation on suicide attempt 
Brokke, Silje S.; Bertelsen, Thomas B.; Landrø, Nils I.; Haaland, Vegard Ø. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Suicide attempt is the most predictive risk factor of suicide. Trauma – especially sexual abuse – is a risk factor for suicide attempt and suicide. A common reaction to sexual abuse is dissociation. ...
Is age of self-harm onset associated with increased frequency of non-suicidal self-injury and suicide attempts in adolescent outpatients? 
Brager-Larsen, Anne; Zeiner, Pål; Klungsøyr, Ole; Mehlum, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Self-harm in adolescents is an increasing public health concern and an important risk factor for suicide. We aimed to examine how age of self-harm onset in adolescents was associated with frequency ...
Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping 
Belloy, Michael E.; Eger, Sarah J.; Le Guen, Yann; Damotte, Vincent; Ahmad, Shahzad; Ikram, M. A.; Ramirez, Alfredo; Tsolaki, Anthoula C.; Rossi, Giacomina; Jansen, Iris E.; de Rojas, Itziar; Parveen, Kayenat; Sleegers, Kristel; Ingelsson, Martin; Hiltunen, Mikko; Amin, Najaf; Andreassen, Ole; Sánchez-Juan, Pascual; Kehoe, Patrick; Amouyel, Philippe; Sims, Rebecca; Frikke-Schmidt, Ruth; van der Flier, Wiesje M.; Lambert, Jean-Charles; He, Zihuai; Han, Summer S.; Napolioni, Valerio; Greicius, Michael D. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Genetic variants within the APOE locus may modulate Alzheimer’s disease (AD) risk independently or in conjunction with APOE*2/3/4 genotypes. Identifying such variants and mechanisms would importantly ...
Paramedic Norwegian Acute Stroke Prehospital Project (ParaNASPP) study protocol: a stepped wedge randomised trial of stroke screening using the National Institutes of Health Stroke Scale in the ambulance 
Bugge, Helge F.; Guterud, Mona; Bache, Kristi C. G.; Braarud, Anne-Cathrine; Eriksen, Erik; Fremstad, Kjell O.; Ihle-Hansen, Hege; Ingebretsen, Svein H.; Kramer-Johansen, Jo; Larsen, Karianne; Røislien, Jo; Thorsen, Kjetil; Toft, Mathias; Sandset, Else Charlotte; Hov, Maren R. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Less than 50% of stroke patients in Norway reach hospital within 4 h of symptom onset. Early prehospital identification of stroke and triage to the right level of care may result in more patients ...
Stakeholder views of the development of a clinical quality registry for interventional radiology: a qualitative study 
Haig, Ylva; Feiring, Eli (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Clinical quality registries (CQRs) can likely improve quality in healthcare and research. However, studies indicate that effective use of CQRs is hindered by lack of engagement and interest among ...
Patients’ and relatives’ perspectives on best possible care in the context of developing a multidisciplinary center for endometriosis and adenomyosis: findings from a national survey 
Omtvedt, Marianne; Bean, Elisabeth; Hald, Kirsten; Larby, Elisabeth R.; Majak, Guri B.; Tellum, Tina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Endometriosis and adenomyosis are common benign conditions compromising both physical and psychological health, with a negative impact on quality of life. This survey aimed to establish what the ...
Exploring drug cost and disease outcome in rheumatoid arthritis patients treated with biologic and targeted synthetic DMARDs in Norway in 2010–2019 – a country with a national tender system for prescription of costly drugs 
Brkic, Alen; Diamantopoulos, Andreas P.; Haavardsholm, Espen A.; Fevang, Bjørg T. S.; Brekke, Lene K.; Loli, Liz; Zettel, Camilla; Rødevand, Erik; Bakland, Gunnstein; Mielnik, Pawel; Haugeberg, Glenn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background In Norway, an annual tender system for the prescription of biologic and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) has been used since 2007. This study aimed to explore ...
Assessment of preoperative axillary nodal disease burden: breast MRI in locally advanced breast cancer before, during and after neoadjuvant endocrine therapy 
Reis, Joana; Boavida, Joao; Tran, Hang T.; Lyngra, Marianne; Reitsma, Laurens C.; Schandiz, Hossein; Melles, Woldegabriel A.; Gjesdal, Kjell-Inge; Geisler, Jürgen; Geitung, Jonn T. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Axillary lymph node (LN) metastasis is one of the most important predictors of recurrence and survival in breast cancer, and accurate assessment of LN involvement is crucial. Determining extent ...
Health-related quality of life in patients with COVID-19; international development of a patient-reported outcome measure 
Amdal, Cecilie D.; Taylor, Katherine; Kuliś, Dagmara; Falk, Ragnhild S.; Bottomley, Andrew; Arraras, Juan I.; Barte, James H.; Darlington, Anne S.; Hofsø, Kristin; Holzner, Bernard; Jørgensen, Nina M. H.; Mariano, Melissa P.; Pe, Madeline; Piccinin, Claire; Riccetti, Nicola; Schranz, Melanie; Wheelwright, Sally; Bjordal, Kristin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background We aimed to create a questionnaire to assess the health-related quality of life including functioning, symptoms, and general health status of adult patients with current or previous COVID-19. ...
Common variants in breast cancer risk loci predispose to distinct tumor subtypes 
Ahearn, Thomas U.; Zhang, Haoyu; Michailidou, Kyriaki; Milne, Roger L.; Bolla, Manjeet K.; Dennis, Joe; Dunning, Alison M.; Lush, Michael; Wang, Qin; Andrulis, Irene L.; Anton-Culver, Hoda; Arndt, Volker; Aronson, Kristan J.; Auer, Paul L.; Augustinsson, Annelie; Baten, Adinda; Becher, Heiko; Behrens, Sabine; Benitez, Javier; Bermisheva, Marina; Blomqvist, Carl; Bojesen, Stig E.; Bonanni, Bernardo; Børresen-Dale, Anne-Lise; Brauch, Hiltrud; Brenner, Hermann; Brooks-Wilson, Angela; Brüning, Thomas; Burwinkel, Barbara; Buys, Saundra S.; Canzian, Federico; Castelao, Jose E.; Chang-Claude, Jenny; Chanock, Stephen J.; Chenevix-Trench, Georgia; Clarke, Christine L.; Collée, J. M.; Cox, Angela; Cross, Simon S.; Czene, Kamila; Daly, Mary B.; Devilee, Peter; Dörk, Thilo; Dwek, Miriam; Eccles, Diana M.; Evans, D. G.; Fasching, Peter A.; Figueroa, Jonine; Floris, Giuseppe; Gago-Dominguez, Manuela; Gapstur, Susan M.; García-Sáenz, José A.; Gaudet, Mia M.; Giles, Graham G.; Goldberg, Mark S.; González-Neira, Anna; Alnæs, Grethe I. G.; Grip, Mervi; Guénel, Pascal; Haiman, Christopher A.; Hall, Per; Hamann, Ute; Harkness, Elaine F.; Heemskerk-Gerritsen, Bernadette A. M.; Holleczek, Bernd; Hollestelle, Antoinette; Hooning, Maartje J.; Hoover, Robert N.; Hopper, John L.; Howell, Anthony; Jakimovska, Milena; Jakubowska, Anna; John, Esther M.; Jones, Michael E.; Jung, Audrey; Kaaks, Rudolf; Kauppila, Saila; Keeman, Renske; Khusnutdinova, Elza; Kitahara, Cari M.; Ko, Yon-Dschun; Koutros, Stella; Kristensen, Vessela N.; Krüger, Ute; Kubelka-Sabit, Katerina; Kurian, Allison W.; Kyriacou, Kyriacos; Lambrechts, Diether; Lee, Derrick G.; Lindblom, Annika; Linet, Martha; Lissowska, Jolanta; Llaneza, Ana; Lo, Wing-Yee; MacInnis, Robert J.; Mannermaa, Arto; Manoochehri, Mehdi; Margolin, Sara; Martinez, Maria E.; McLean, Catriona; Meindl, Alfons; Menon, Usha; Nevanlinna, Heli; Newman, William G.; Nodora, Jesse; Offit, Kenneth; Olsson, Håkan; Orr, Nick; Park-Simon, Tjoung-Won; Patel, Alpa V.; Peto, Julian; Pita, Guillermo; Plaseska-Karanfilska, Dijana; Prentice, Ross; Punie, Kevin; Pylkäs, Katri; Radice, Paolo; Rennert, Gad; Romero, Atocha; Rüdiger, Thomas; Saloustros, Emmanouil; Sampson, Sarah; Sandler, Dale P.; Sawyer, Elinor J.; Schmutzler, Rita K.; Schoemaker, Minouk J.; Schöttker, Ben; Sherman, Mark E.; Shu, Xiao-Ou; Smichkoska, Snezhana; Southey, Melissa C.; Spinelli, John J.; Swerdlow, Anthony J.; Tamimi, Rulla M.; Tapper, William J.; Taylor, Jack A.; Teras, Lauren R.; Terry, Mary B.; Torres, Diana; Troester, Melissa A.; Vachon, Celine M.; van Deurzen, Carolien H. M.; van Veen, Elke M.; Wagner, Philippe; Weinberg, Clarice R.; Wendt, Camilla; Wesseling, Jelle; Winqvist, Robert; Wolk, Alicja; Yang, Xiaohong R.; Zheng, Wei; Couch, Fergus J.; Simard, Jacques; Kraft, Peter; Easton, Douglas F.; Pharoah, Paul D. P.; Schmidt, Marjanka K.; García-Closas, Montserrat; Chatterjee, Nilanjan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) ...
Frequency and predictors of unspecific medical diagnoses in the emergency department: a prospective observational study 
Birrenbach, Tanja; Hoffmann, Michele; Hautz, Stefanie C.; Kämmer, Juliane E.; Exadaktylos, Aristomenis K.; Sauter, Thomas C.; Müller, Martin; Hautz, Wolf E. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Misdiagnosis is a major public health problem, causing increased morbidity and mortality. In the busy setting of an emergency department (ED) patients are diagnosed under difficult circumstances. ...
“It was an important part of my treatment”: a qualitative study of Norwegian breast Cancer patients’ experiences with mainstreamed genetic testing 
Strømsvik, Nina; Olsson, Pernilla; Gravdehaug, Berit; Lurås, Hilde; Schlichting, Ellen; Jørgensen, Kjersti; Wangensteen, Teresia; Vamre, Tone; Heramb, Cecilie; Mæhle, Lovise; Grindedal, Eli M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background In South-Eastern Norway, genetic testing for BRCA1 and BRCA2 is offered to breast cancer patients by their treating surgeon or oncologist. Genetic counselling from a geneticist or a genetic ...
Experienced fatigue in people with rare disorders: a scoping review on characteristics of existing research 
Bathen, Trine; Johansen, Heidi; Strømme, Hilde; Velvin, Gry (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Experienced fatigue is an under-recognized and under-researched feature in persons with many different rare diseases. A better overview of the characteristics of existing research on experienced ...
Attitudes towards priority setting in the norwegian health care system: a general population survey 
Solberg, Carl T.; Tranvåg, Eirik J.; Magelssen, Morten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background In an ideal world, everyone would receive medical resources in accordance with their needs. In reality, resources are often scarce and have an alternative use. Thus, we are forced to prioritize. ...
Estimation of the historical dry deposition of air pollution indoors to the monumental paintings by Edvard Munch in the University Aula, in Oslo, Norway 
Grøntoft, Terje; Frøysaker, Tine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
The historical (1835–2020) deposition of major air pollutants (SO2, NOx, O3 and PM2.5) indoors, as represented by the monumental Edvard Munch paintings (c. 220 m2) installed in 1916 in the Oslo University Aula in Norway, ...
Characterizing the bioburden of ESBL-producing organisms in a neonatal unit using chromogenic culture media: a feasible and efficient environmental sampling method 
Vurayai, Moses; Strysko, Jonathan; Kgomanyane, Kgomotso; Bayani, One; Mokomane, Margaret; Machiya, Tichaona; Arscott-Mills, Tonya; Goldfarb, David M.; Steenhoff, Andrew P.; McGann, Carolyn; Nakstad, Britt; Gezmu, Alemayehu; Richard-Greenblatt, Melissa; Coffin, Susan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Introduction Infections due to extended spectrum beta-lactamase producing organisms (ESBL) have emerged as the leading cause of sepsis among hospitalized neonates in Botswana and much of sub-Saharan Africa ...
Associations between personal recovery and service user-rated versus clinician-rated clinical recovery, a cross-sectional study 
Skar-Fröding, Regina; Clausen, Hanne; Šaltytė Benth, Jūratė; Ruud, Torleif; Slade, Mike; S. Heiervang, Kristin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background This study examined the relationship between service user-rated personal recovery and clinician-rated and service user-rated clinical recovery. The relationships between different subdomains of ...
The efficacy of pivmecillinam in oral step-down treatment in hospitalised patients with E. coli bacteremic urinary tract infection; a single-arm, uncontrolled treatment study 
Hansen, Bjørn Å.; Grude, Nils; Lindbæk, Morten; Stenstad, Tore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The role of oral beta-lactam antibiotics in treating febrile urinary tract infections (UTI) is not yet definite. Today, fluoroquinolones together with trimethoprim–sulfamethoxazole (TMP–MTX) are ...
Evaluation of statistical approaches for association testing in noisy drug screening data 
Smirnov, Petr; Smith, Ian; Safikhani, Zhaleh; Ba-alawi, Wail; Khodakarami, Farnoosh; Lin, Eva; Yu, Yihong; Martin, Scott; Ortmann, Janosch; Aittokallio, Tero; Hafner, Marc; Haibe-Kains, Benjamin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Identifying associations among biological variables is a major challenge in modern quantitative biological research, particularly given the systemic and statistical noise endemic to biological ...
A compelling demonstration of why traditional statistical regression models cannot be used to identify risk factors from case data on infectious diseases: a simulation study 
Engebretsen, Solveig; Rø, Gunnar; de Blasio, Birgitte F. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Regression models are often used to explain the relative risk of infectious diseases among groups. For example, overrepresentation of immigrants among COVID-19 cases has been found in multiple ...
Correction to: Location of studies and evidence of effects of herbivory on Arctic vegetation: a systematic map 
Soininen, Eeva M.; Barrio, Isabel C.; Bjørkås, Ragnhild; Björnsdóttir, Katrín; Ehrich, Dorothee; Hopping, Kelly; Kaarlejärvi, Elina; Kolstad, Anders L.; Abdulmanova, Svetlana; Björk, Robert G.; Bueno, C. G.; Eischeid, Isabell; Higgens, Rebecca F.; Forbey, Jennifer S.; Gignac, Charles; Gilg, Olivier; den Herder, Michael; Holm, Hildur S.; Hwang, Bernice C.; Jepsen, Jane U.; Kamenova, Stefaniya; Kater, Ilona; Koltz, Amanda M.; Kristensen, Jeppe A.; Little, Chelsea J.; Macek, Petr; Mathisen, Karen M.; Metcalfe, Daniel; Mosbacher, Jesper B.; Mörsdorf, Martin A.; Park, Taejin; Propster, Jeffrey; Roberts, Aradhana; Ferron, Emmanuel S.; Spiegel, Marcus P.; Tamayo, Mariana; Tuomi, Maria W.; Verma, Megha; Vuorinen, Katariina E. M.; Väisänen, Maria; Van der Wal, René; Wilcots, Megan; Yoccoz, Nigel; Speed, James D. M. (Journal article / Tidsskriftartikkel / PublishedVersion, 2022)
Pegs not superior to screws for fixation of fractures of the proximal humerus 
Bønes, Ingrid; Karlberg, Anna C.; Liljeholm, Maria; Fraser, Alexander N.; Madsen, Jan E.; Fjalestad, Tore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Angular stable plates were introduced two decades ago as a promising treatment for fixation of displaced fractures of the proximal humerus (PHF). However, high rates of adverse events and ...
Balancing standardisation and individualisation in transitional care pathways: a meta-ethnography of the perspectives of older patients, informal caregivers and healthcare professionals 
Kvæl, Linda A. H.; Hellesø, Ragnhild; Bergland, Astrid; Debesay, Jonas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Transitional care implies the transfer of patients within or across care settings in a seamless and safe way. For frail, older patients with complex health issues, high-quality transitions are ...
Impact of a dementia-friendly program on detection and management of patients with cognitive impairment and delirium in acute-care hospital units: a controlled clinical trial design 
Weldingh, NM; Mellingsæter, MR; Hegna, BW; Benth, J Saltyte; Einvik, G; Juliebø, V; Thommessen, B; Kirkevold, M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Frail older persons with cognitive impairment (CI) are at special risk of experiencing delirium during acute hospitalisation. The purpose of this study was to investigate whether a dementia-friendly ...
Incidence of breast cancer subtypes in immigrant and non-immigrant women in Norway 
Hjerkind, Kirsti V.; Johansson, Anna L. V.; Trewin, Cassia B.; Russnes, Hege G.; Ursin, Giske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Breast cancer incidence differs between non-immigrants and immigrants from low- and middle-income countries. This study investigates whether immigrants also have different subtype-specific ...
Whole-body biodistribution and radiation dosimetry of [18F]PR04.MZ: a new PET radiotracer for clinical management of patients with movement disorders 
Lehnert, Wencke; Riss, Patrick J.; Hurtado de Mendoza, Ana; Lopez, Sandra; Fernandez, Gonzalo; Ilheu, Marcelo; Amaral, Horacio; Kramer, Vasko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Purpose [18F]PR04.MZ is a new PET imaging agent for dopamine transporters, providing excellent image quality and allowing for the evaluation of patients with movement disorders such as Parkinson’s disease. ...
Effects of a school-based intervention on levels of anxiety and depression: a cluster-randomized controlled trial of the MindPower program in ten high schools in Norway 
Sælid, Gry A.; Czajkowski, Nikolai O.; Aarø, Leif E.; Andersen, John R.; Idsøe, Thormod; Helleseter, Miguel D.; Holte, Arne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The previous decades have shown increased symptoms of depression and anxiety among adolescents. To promote mental health and reduce mental illness, the government of Norway has, as in other ...
The relationship of acute delirium with cognitive and psychiatric symptoms after stroke: a longitudinal study 
Nerdal, Vilde; Gjestad, Elise; Saltvedt, Ingvild; Munthe-Kaas, Ragnhild; Ihle-Hansen, Hege; Ryum, Truls; Lydersen, Stian; Grambaite, Ramune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Objective Delirium, a common complication after stroke, is often overlooked, and long-term consequences are poorly understood. This study aims to explore whether delirium in the acute phase of stroke predicts ...
Incidence of emergency neurosurgical TBI procedures: a population-based study 
Tverdal, Cathrine; Aarhus, Mads; Rønning, Pål; Skaansar, Ola; Skogen, Karoline; Andelic, Nada; Helseth, Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The rates of emergency neurosurgery in traumatic brain injury (TBI) patients vary between populations and trauma centers. In planning acute TBI treatment, knowledge about rates and incidence of ...
Joint effect of particulate matter and cigarette smoke on women’s sex hormones 
Merklinger-Gruchala, Anna; Jasienska, Grazyna; Thune, Inger; Kapiszewska, Maria (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Although relationships between exposure to air pollution and reproductive health are broadly studied, mechanisms behind these phenomena are still unknown. The aim of the study was to assess whether ...
Modifiable and non-modifiable risk factors for obstetric anal sphincter injury in a Norwegian Region: a case–control study 
Klokk, Ragnhild; Bakken, Kjersti S.; Markestad, Trond; Holten-Andersen, Mads N. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Obstetric anal sphincter injury (OASI) is a common and severe complication of vaginal delivery and may have short- and long-term consequences, including anal incontinence, sexual dysfunction and ...
Visual impairment and employment in Norway 
Brunes, Audun; Heir, Trond (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Past studies have suggested lower employment of people with visual impairment. Reasons for this are less known. This study aimed to examine the employment rates among people with visual impairment, ...
The long-term effect of job mobility on workers’ mental health: a propensity score analysis 
Maniscalco, Laura; Schouteden, Martijn; Boon, Jan; Vandenbroeck, Sofie; Mehlum, Ingrid S.; Godderis, Lode; Matranga, Domenica (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Objectives The main purpose of this longitudinal study was to elucidate the impact of external job mobility, due to a change of employer, on mental health. ...
Group treatment for complex dissociative disorders: a randomized clinical trial 
Bækkelund, Harald; Ulvenes, Pål; Boon-Langelaan, Suzette; Arnevik, Espen A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Patients with complex dissociative disorders (CDD) report high levels of childhood- abuse experiences, clinical comorbidity, functional impairment, and treatment utilization. Although a few ...
Nursing students’ development of using physical assessment in clinical rotation—a stimulated recall study 
Byermoen, Kirsten R.; Eide, Tom; Egilsdottir, H. Ö.; Eide, Hilde; Heyn, Lena G.; Moen, Anne; Brembo, Espen A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The overall aim of this study was to explore third-year bachelor nursing students’ stimulated recall reflections on their physical assessment competence development. The choice of learning ...
Reliability of preoperative MRI findings in patients with lumbar spinal stenosis 
Banitalebi, Hasan; Espeland, Ansgar; Anvar, Masoud; Hermansen, Erland; Hellum, Christian; Brox, Jens I.; Myklebust, Tor Å.; Indrekvam, Kari; Brisby, Helena; Weber, Clemens; Aaen, Jørn; Austevoll, Ivar M.; Grundnes, Oliver; Negård, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Magnetic Resonance Imaging (MRI) is an important tool in preoperative evaluation of patients with lumbar spinal stenosis (LSS). Reported reliability of various MRI findings in LSS varies from ...
Premature mortality attributable to COVID-19: potential years of life lost in 17 countries around the world, January–August 2020 
Ugarte, Maider P.; Achilleos, Souzana; Quattrocchi, Annalisa; Gabel, John; Kolokotroni, Ourania; Constantinou, Constantina; Nicolaou, Nicoletta; Rodriguez-Llanes, Jose M.; Huang, Qian; Verstiuk, Olesia; Pidmurniak, Nataliia; Tao, Jennifer W.; Burström, Bo; Klepac, Petra; Erzen, Ivan; Chong, Mario; Barron, Manuel; Hagen, Terje P.; Kalmatayeva, Zhanna; Davletov, Kairat; Zucker, Inbar; Kaufman, Zalman; Kereselidze, Maia; Kandelaki, Levan; Le Meur, Nolwenn; Goldsmith, Lucy; Critchley, Julia A.; Pinilla, Maria A.; Jaramillo, Gloria I.; Teixeira, Domingos; Goméz, Lara F.; Lobato, Jackeline; Araújo, Carolina; Cuthbertson, Joseph; Bennett, Catherine M.; Polemitis, Antonis; Charalambous, Andreas; Demetriou, Christiana A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Understanding the impact of the burden of COVID-19 is key to successfully navigating the COVID-19 pandemic. As part of a larger investigation on COVID-19 mortality impact, this study aims to ...
Similarities and differences between service users’ and carers’ experiences of crisis resolution teams in Norway: a survey 
Hasselberg, Nina; Klevan, Trude G.; Weimand, Bente; Uverud, Gunn-Marit; Holgersen, Katrine H.; Siqveland, Johan; Ruud, Torleif (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Crisis resolution team (CRT) care in adult mental health services is intended to provide accessible and flexible short-term, intensive crisis intervention to service users experiencing a mental ...
Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors 
Dahlberg, Daniel; Rummel, Jutta; Distante, Sonia; De Souza, Gustavo A.; Stensland, Maria E.; Mariussen, Espen; Rootwelt, Helge; Voie, Øyvind; Hassel, Bjørnar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The growth of malignant tumors is influenced by their microenvironment. Glioblastoma, an aggressive primary brain tumor, may have cysts containing fluid that represents the tumor microenvironment. ...
Reducing low-value radiological services in Norway –a qualitative multi-professional study on measures and facilitators for change 
Andersen, Eivind R.; Hofmann, Bjørn M.; Kjelle, Elin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Overuse, underuse, and significant variation in the utilisation of radiological services are well documented in the literature. Several radiological examinations are identified as low-value ...
Unspecified opioids among opioid overdoses in Oslo, Norway 
Iqbal, Zahra Z.; Nguyen, Thanh M. T.; Brekke, Mette; Vallersnes, Odd M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Objective Since 2017, an increasing number of opioid overdoses in Oslo, Norway, has been categorized as involving unspecified opioids, as noted in the patient records by the doctor treating the patient. In ...
Proximal Hamstring Tendon Avulsions: A Survey of Orthopaedic Surgeons’ Current Practices in the Nordic Countries 
Laszlo, Sofia; Nilsson, Martin; Pihl, Elsa; Mattila, Ville M.; Schilcher, Jörg; Sköldenberg, Olof; Frihagen, Frede; Jonsson, Kenneth B. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background and purpose Evidence guiding the decision on whether to treat proximal hamstring tendon avulsions (PHA) operatively or non-operatively is very limited. The aim of this study was to identify the ...
Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage 
Madsen-Østerbye, Julia; Abdelhalim, Mohamed; Baudement, Marie-Odile; Collas, Philippe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Interactions of chromatin with the nuclear lamina via lamina-associated domains (LADs) confer structural stability to the genome. The dynamics of positioning of LADs during differentiation, and ...
Equal opportunities for all? Analyzing within-country variation in school effectiveness 
Steinmann, Isa; Olsen, Rolf V. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The present study addresses the equality of school effectiveness across schools. One central aim of compulsory education is for students to learn equally well at all schools in a country even ...
Mortality in nursing home residents stratified according to subtype of dementia: a longitudinal study over three years 
Vossius, Corinna; Bergh, Sverre; Selbæk, Geir; Benth, Jūratė Š.; Myhre, Janne; Aakhus, Eivind; Lichtwarck, Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background There are several subtypes of dementia caused by different pathophysiology and with different clinical characteristics. Irrespective subtype, the disease is progressive, eventually leading to the ...
Emergency cricothyroidotomy in difficult airway simulation – a national observational study of Air Ambulance crew performance 
Andresen, Åke E. L.; Kramer-Johansen, Jo; Kristiansen, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Advanced prehospital airway management includes complex procedures carried out in challenging environments, necessitating a high level of technical and non-technical skills. We aimed to describe ...
What ethical approaches are used by scientists when sharing health data? An interview study 
Viberg Johansson, Jennifer; Bentzen, Heidi B.; Mascalzoni, Deborah (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Health data-driven activities have become central in diverse fields (research, AI development, wearables, etc.), and new ethical challenges have arisen with regards to privacy, integrity, and ...
Frameworks for implementation of policies promoting healthy nutrition and physically active lifestyle: systematic review 
Lobczowska, Karolina; Banik, Anna; Romaniuk, Piotr; Forberger, Sarah; Kubiak, Thomas; Meshkovska, Biljana; Neumann-Podczaska, Agnieszka; Kaczmarek, Krzysztof; Scheidmeir, Marie; Wendt, Janine; Scheller, Daniel A.; Wieczorowska-Tobis, Katarzyna; Steinacker, Juergen M.; Zeeb, Hajo; Luszczynska, Aleksandra (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Policy frameworks focusing on policy implementation may vary in terms of their scope, included constructs, relationships between the constructs, and context factors. Although multiple policy ...
Cost-effectiveness analysis of combined cognitive and vocational rehabilitation in patients with mild-to-moderate TBI: results from a randomized controlled trial 
Howe, Emilie I.; Andelic, Nada; Fure, Silje C R.; Røe, Cecilie; Søberg, Helene L.; Hellstrøm, Torgeir; Spjelkavik, Øystein; Enehaug, Heidi; Lu, Juan; Ugelstad, Helene; Løvstad, Marianne; Aas, Eline (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Traumatic brain injury (TBI) represents a financial burden to the healthcare system, patients, their families and society. Rehabilitation interventions with the potential for reducing costs ...
A help or hindrance? Highly educated refugees’ perceptions of the role of civic integration programmes in accessing the labour market in Oslo, Malmö and Munich 
Mozetič, Katarina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Research often focuses on individual-level factors shaping refugee labour market participation. Less research has been conducted on the implications of the roles of employers, integration programmes, migrant support ...
Assessment of maternal and child health care services performance in the context of COVID-19 pandemic in Addis Ababa, Ethiopia: evidence from routine service data 
Gebreegziabher, Senedu B.; Marrye, Solomon S.; Kumssa, Tsegaye H.; Merga, Kassa H.; Feleke, Alemu K.; Dare, Degu J.; Hallström, Inger K.; Yimer, Solomon A.; Shargie, Mulatu B. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background In many settings, health care service provision has been modified to managing COVID-19 cases, and this has been affecting the provision of maternal and child health services. The aim of this ...
Comparative efficacy and safety of infliximab and vedolizumab therapy in patients with inflammatory bowel disease: a systematic review and meta-analysis 
Peyrin-Biroulet, Laurent; Arkkila, Perttu; Armuzzi, Alessandro; Danese, Silvio; Guardiola, Jordi; Jahnsen, Jørgen; Lees, Charles; Louis, Edouard; Lukáš, Milan; Reinisch, Walter; Roblin, Xavier; Jang, Minyoung; Byun, Han G.; Kim, Dong-Hyeon; Lee, Sung J.; Atreya, Raja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background and aims There are limited comparative data for infliximab and vedolizumab in inflammatory bowel disease patients. Methods We conducted ...
Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss 
Simeone, Paola; Tripaldi, Romina; Michelsen, Annika; Ueland, Thor; Liani, Rossella; Ciotti, Sonia; Birkeland, Kåre I.; Gulseth, Hanne L.; Di Castelnuovo, Augusto; Cipollone, Francesco; Aukrust, Pål; Consoli, Agostino; Halvorsen, Bente; Santilli, Francesca (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Soluble suppression of tumorigenesis-2 (sST2) and galectin (Gal)-3 are two biomarkers related to inflammation, metabolic disturbances and to myocardial fibrosis that characterize several cardiac ...
Medical students’ experiences when empathizing with patients’ emotional issues during a medical interview – a qualitative study 
Brodahl, Knut Ø.; Storøy, Hanne-Lise E.; Finset, Arnstein; Pedersen, Reidar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background There is evidence that empathy decreases as medical students go through clinical training. However, there are few in-depth studies investigating the students’ own experiences when trying to ...
Health communication in and out of public health emergencies: to persuade or to inform? 
Oxman, Andrew D.; Fretheim, Atle; Lewin, Simon; Flottorp, Signe; Glenton, Claire; Helleve, Arnfinn; Vestrheim, Didrik F.; Iversen, Bjørn G.; Rosenbaum, Sarah E. (Journal article / Tidsskriftartikkel / PublishedVersion, 2022)
Much health communication during the COVID-19 pandemic has been designed to persuade people more than to inform them. For example, messages like “masks save lives” are intended to compel people to wear face masks, not to ...
K∗ (892)0 meson production in inelastic p+p interactions at 40 and 80 GeV/c beam momenta measured by NA61/SHINE at the CERN SPS 
Acharya, A.; Adhikary, H.; Allison, K. K.; Amin, N.; Andronov, E. V.; Antićić, T.; Arsene, I. -.; Baszczyk, M.; Battagia, D.; Bhosale, S.; Blondel, A.; Bogomilov, M.; Bondar, Y.; Bostan, N.; Brandin, A.; Bravar, A.; Bryliński, W.; Brzychczyk, J.; Buryakov, M.; Ćirković, M.; Csanad, M.; Cybowska, J.; Czopowicz, T.; Damyanova, A.; Davis, N.; Dmitriev, A.; Dominik, W.; Dorosz, P.; Dumarchez, J.; Engel, R.; Feofilov, G. A.; Fields, L.; Fodor, Z.; Friend, M.; Garibov, A.; Gaździcki, M.; Golosov, O.; Golovatyuk, V.; Golubeva, M.; Grebieszkow, K.; Guber, F.; Haesler, A.; Igolkin, S. N.; Ilieva, S.; Ivashkin, A.; Izvestnyy, A.; Johnson, S. R.; Kadija, K.; Kargin, N.; Karpushkin, N.; Kashirin, E.; Kiełbowicz, M.; Kireyeu, V. A.; Kolesnikov, R.; Kolev, D.; Korzenev, A.; Koshio, J.; Kovalenko, V. N.; Kowalski, S.; Kozłowski, B.; Krasnoperov, A.; Kucewicz, W.; Kuich, M.; Kurepin, A.; László, A.; Lewicki, M.; Łojek, K.; Lykasov, G.; Lyubushkin, V. V.; Maćkowiak-Pawłowska, M.; Majka, Z.; Makhnev, A.; Maksiak, B.; Malakhov, A. I.; Marcinek, A.; Marino, A. D.; Marton, K.; Mathes, H. -.; Matulewicz, T.; Matveev, V.; Matyja, A.; Melkumov, G. L.; Merzlaya, A.; Merzlaya, A. O.; Messerly, B.; Mik, Ł.; Morozov, S.; Nagai, Y.; Nakadaira, T.; Naskręt, M.; Ozvenchuk, V.; Panova, O.; Paolone, V.; Petukhov, O.; Pidhurskyi, I.; Płaneta, R.; Podlaski, P.; Popov, B. A.; Porfy, B.; Posiadała-Zezula, M.; Prokhorova, D. S.; Pszczel, D.; Puławski, S.; Puzović, J.; Ravonel, M.; Renfordt, R.; Röhrich, D.; Rondio, E.; Roth, M.; Rumberger, B. T.; Rumyantsev, M.; Rustamov, A.; Rybczynski, M.; Rybicki, A.; Sadhu, S.; Sakashita, K.; Schmidt, K.; Selyuzhenkov, I.; Seryakov, A. Y.; Seyboth, P.; Słodkowski, M.; Staszel, P.; Stefanek, G.; Stepaniak, J.; Strikhanov, M.; Ströbele, H.; Šuša, T.; Taranenko, A.; Tefelska, A.; Tefelski, D.; Tereshchenko, V.; Toia, A.; Tsenov, R.; Turko, L.; Tveter, T. S.; Unger, M.; Valiev, F. F.; Veberič, D.; Vechernin, V. V.; Volkov, V.; Wickremasinghe, A.; Wójcik, K.; Wyszyński, O.; Zaitsev, A.; Zimmerman, E. D.; Zviagina, A.; Zwaska, R. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Measurements of K∗ (892)0 resonance production via its K+ π − decay mode in inelastic p+p collisions at beam momenta 40 and 80 GeV/c (√sNN = 8.8 and 12.3 GeV) are presented. The data were recorded by the NA61/SHINE hadron ...
The partial µ-opioid agonist buprenorphine in autism spectrum disorder: a case report 
Skoglund, Charlotte; Leknes, Siri; Heilig, Markus (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background There are currently no approved medications for impaired social cognition and function, core symptoms of autism spectrum disorder. We describe marked improvement of these symptoms with long-term ...
Precious blood and nourishing offal: past and present slaughtering perspectives in Sámi reindeer pastoralism 
Sara, Ravdna B. M. E.; Syse, Karen L.; Mathiesen, Svein D. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
In the Arctic, indigenous reindeer herding peoples rely on a pastoralist food and knowledge system that supplies them with protein, vitamins, and minerals. Reindeer pastoralism is a product of the interaction between ...
Locked out during COVID-19 lockdown—an online survey of relatives of people with psychotic and bipolar disorders in Norway 
Aminoff, Sofie R.; Mork, Erlend; Barrett, Elizabeth A.; Simonsen, Carmen; ten Velden Hegelstad, Wenche; Lagerberg, Trine V.; Melle, Ingrid; Romm, Kristin L. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Many relatives of people with psychotic and bipolar disorders experience a high caregiver burden normally. During the first COVID-19 lockdown, mental health services partly shut down in many ...
COVID-19 lockdown – who cares? The first lockdown from the perspective of relatives of people with severe mental illness 
Mork, Erlend; Aminoff, Sofie R.; Barrett, Elizabeth A.; Simonsen, Carmen; Hegelstad, Wenche t. V.; Lagerberg, Trine V.; Melle, Ingrid; Romm, Kristin L. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Informal care is vital to many people with severe mental illness under normal circumstances. Little is known about how extraordinary circumstances affect relatives with a family member with mental ...
Knowledge, attitudes and practices related to Taenia solium cysticercosis and taeniasis in Tanzania 
Nyangi, Chacha; Stelzle, Dominik; Mkupasi, Ernatus M.; Ngowi, Helena A.; Churi, Ayubu J.; Schmidt, Veronika; Mahonge, Christopher; Winkler, Andrea S. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background Taenia solium cysticercosis/taeniasis (TSCT) is reported to be endemic in pig producing areas around the world, causing significant disease burden and economic losses. ...
The prevalence and incidence of pharmacologically treated diabetes among older people receiving home care services in Norway 2009–2014: a nationwide longitudinal study 
Teigland, Tonje; Igland, Jannicke; Tell, Grethe S.; Haltbakk, Johannes; Graue, Marit; Fismen, Anne-Siri; Birkeland, Kåre I.; Østbye, Truls; Peyrot, Mark; Iversen, Marjolein M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background A substantial proportion of older people who receive home care services (HCS) has diabetes and requires diabetes specific monitoring, treatment and self-care assistance. However, the prevalence ...
A nationwide registry study on heart failure in Norway from 2008 to 2018: variations in lookback period affect incidence estimates 
Ødegaard, Kristina M.; Lirhus, Sandre S.; Melberg, Hans O.; Hallén, Jonas; Halvorsen, Sigrun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background The incidence of heart failure (HF) has declined in Europe during the past two decades. However, incidence estimates from registry-based studies may vary, partly because they depend on retrospective ...
COVAX, vaccine donations and the politics of global vaccine inequity 
de Bengy Puyvallée, Antoine; Storeng, Katerini T. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background In 2021, donor countries, the pharmaceutical industry, and the COVAX initiative promoted vaccine donation or “dose-sharing” as a main solution to the inequitable global distribution of Covid-19 ...
Nanoparticle classification, physicochemical properties, characterization, and applications: a comprehensive review for biologists 
Joudeh, Nadeem; Linke, Dirk (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Interest in nanomaterials and especially nanoparticles has exploded in the past decades primarily due to their novel or enhanced physical and chemical properties compared to bulk material. These extraordinary properties ...
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