Browsing BioMed Central høstingsarkiv by Author "Kalimo, Hannu"

Now showing items 1-1 of 1

  • The Arctic AβPP mutation leads to Alzheimer’s disease pathology with highly variable topographic deposition of differentially truncated Aβ 
    Kalimo, Hannu; Lalowski, Maciej; Bogdanovic, Nenad; Philipson, Ola; Bird, Thomas D; Nochlin, David; Schellenberg, Gerard D; Brundin, RoseMarie; Olofsson, Tommie; Soliymani, Rabah; Baumann, Marc; Wirths, Oliver; Bayer, Thomas A; Nilsson, Lars N; Basun, Hans; Lannfelt, Lars; Ingelsson, Martin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background The Arctic mutation (p.E693G/p.E22G)fs within the β-amyloid (Aβ) region of the β-amyloid precursor protein gene causes an autosomal dominant disease with clinical picture of typical Alzheimer’s ...