Browsing BioMed Central høstingsarkiv by Author "Udugama, Maheshi"

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  • Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies 
    Voon, Hsiao P. J.; Hii, Linda; Garvie, Andrew; Udugama, Maheshi; Krug, Brian; Russo, Caterina; Chüeh, Anderly C.; Daly, Roger J.; Morey, Alison; Bell, Toby D. M.; Turner, Stephen J.; Rosenbluh, Joseph; Daniel, Paul; Firestein, Ron; Mann, Jeffrey R.; Collas, Philippe; Jabado, Nada; Wong, Lee H. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Point mutations in histone variant H3.3 (H3.3K27M, H3.3G34R) and the H3.3-specific ATRX/DAXX chaperone complex are frequent events in pediatric gliomas. These H3.3 point mutations affect many ...