Browsing BioMed Central høstingsarkiv by Author "Pagnon de la Vega, María"

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  • Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion 
    Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique; Konstantinidis, Evangelos; Meier, Silvio R.; Rokka, Johanna; Eriksson, Jonas; Aguilar, Ximena; Spires-Jones, Tara L.; Lannfelt, Lars; Nilsson, Lars N. G.; Erlandsson, Anna; Hultqvist, Greta; Ingelsson, Martin; Sehlin, Dag (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
    Deposition of amyloid beta (Aβ) into plaques is a major hallmark of Alzheimer’s disease (AD). Different amyloid precursor protein (APP) mutations cause early-onset AD by altering the production or aggregation properties ...