Now showing items 1-6 of 6

  • Nustad, Haakon E; Page, Christian M; Reiner, Andrew H; Zucknick, Manuela; LeBlanc, Marissa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background A Bayesian mixed model approach using integrated nested Laplace approximations (INLA) allows us to construct flexible models that can account for pedigree structure. Using these models, we estimate ...
  • Haftorn, Kristine L; Lee, Yunsung; Denault, William R P; Page, Christian M; Nustad, Haakon E; Lyle, Robert; Gjessing, Håkon K; Malmberg, Anni; Magnus, Maria C; Næss, Øyvind; Czamara, Darina; Räikkönen, Katri; Lahti, Jari; Magnus, Per; Håberg, Siri E; Jugessur, Astanand; Bohlin, Jon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Gestational age is a useful proxy for assessing developmental maturity, but correct estimation of gestational age is difficult using clinical measures. DNA methylation at birth has proven to be ...
  • Lee, Yunsung; Haftorn, Kristine L; Denault, William R P; Nustad, Haakon E; Page, Christian M; Lyle, Robert; Lee-Ødegård, Sindre; Moen, Gunn-Helen; Prasad, Rashmi B; Groop, Leif C; Sletner, Line; Sommer, Christine; Magnus, Maria C; Gjessing, Håkon K; Harris, Jennifer R; Magnus, Per; Håberg, Siri E; Jugessur, Astanand; Bohlin, Jon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background Epigenetic clocks have been recognized for their precise prediction of chronological age, age-related diseases, and all-cause mortality. Existing epigenetic clocks are based on CpGs from the ...
  • Bucher-Johannessen, Cecilie; Page, Christian M; Haugen, Trine B; Wojewodzic, Marcin W; Fosså, Sophie D; Grotmol, Tom; Haugnes, Hege S; Rounge, Trine B (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Cisplatin-based chemotherapy (CBCT) is part of standard treatment of several cancers. In testicular cancer (TC) survivors, an increased risk of developing metabolic syndrome (MetS) is observed. ...
  • Nustad, Haakon E; Almeida, Marcio; Canty, Angelo J; LeBlanc, Marissa; Page, Christian M; Melton, Phillip E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Longitudinal data and repeated measurements in epigenome-wide association studies (EWAS) provide a rich resource for understanding epigenetics. We summarize 7 analytical approaches to the GAW20 ...
  • LeBlanc, Marissa; Nustad, Haakon E; Zucknick, Manuela; Page, Christian M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background An important feature in many genomic studies is quality control and normalization. This is particularly important when analyzing epigenetic data, where the process of obtaining measurements can ...