Browsing BioMed Central høstingsarkiv by Author "Paarmann, Kristin"

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  • Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice 
    Steffen, Johannes; Krohn, Markus; Schwitlick, Christina; Brüning, Thomas; Paarmann, Kristin; Pietrzik, Claus U; Biverstål, Henrik; Jansone, Baiba; Langer, Oliver; Pahnke, Jens (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Amyloid-β (Aβ) deposition is one of the hallmarks of the amyloid hypothesis in Alzheimer’s disease (AD). Mouse models using APP-transgene overexpression to generate amyloid plaques have shown to model only certain parts ...
  • Revisiting rodent models: Octodon degus as Alzheimer’s disease model? 
    Steffen, Johannes; Krohn, Markus; Paarmann, Kristin; Schwitlick, Christina; Brüning, Thomas; Marreiros, Rita; Müller-Schiffmann, Andreas; Korth, Carsten; Braun, Katharina; Pahnke, Jens (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Alzheimer’s disease primarily occurs as sporadic disease and is accompanied with vast socio-economic problems. The mandatory basic research relies on robust and reliable disease models to overcome increasing incidence and ...