Browsing Institutt for klinisk medisin by Title

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  • H2S-Enriched Flush out Does Not Increase Donor Organ Quality in a Porcine Kidney Perfusion Model 
    Maassen, Hanno; Venema, Leonie H.; Weiss, Marc G.; Huijink, Tobias M.; Hofker, H. Sijbrand; Keller, Anna K.; Mollnes, Tom Eirik; Eijken, Marco; Pischke, Soeren; Jespersen, Bente; van Goor, Harry; Leuvenink, Henri G. D. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Kidney extraction time has a detrimental effect on post-transplantation outcome. This study aims to improve the flush-out and potentially decrease ischemic injury by the addition of hydrogen sulphide (H2S) to the flush ...
  • Haemodynamic changes during spinal anaesthesia for caesarean section 
    Langesæter, Eldrid (Doctoral thesis / Doktoravhandling, 2009)
    Ny kunnskap om spinalbedøvelse ved keisersnitt<br> Symptomer som hjertebank, pusteproblemer, svimmelhet, kvalme og oppkast er kjente bivirkninger av blodtrykksfall ved spinalbedøvelse til keisersnitt. Anestesilege og ...
  • Haemodynamic effects of methoxyflurane versus fentanyl and placebo in hypovolaemia: a randomised, double-blind crossover study in healthy volunteers 
    Høiseth, Lars Øivind; FJOSE, LARS OLAV; Hisdal, Jonny; Comelon, Marlin; Rosseland, Leiv Arne; Lenz, Harald (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Methoxyflurane is approved for relief of moderate to severe pain in conscious adult trauma patients: it may be self-administrated and is well suited for use in austere environments. Trauma patients may sustain ...
  • Haemodynamic outcomes during piston-based mechanical CPR with or without active decompression in a porcine model of cardiac arrest 
    Steinberg, Mikkel T; Olsen, Jan-Aage; Eriksen, Morten; Neset, Andres; Norseng, Per A; Kramer-Johansen, Jo; Hardig, Bjarne M; Wik, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Experimental active compression-decompression (ACD) CPR is associated with increased haemodynamic outcomes compared to standard mechanical chest compressions. Since no clinically available ...
  • Haemodynamics during Vaginal and Caesarean Delivery in Healthy Parturients 
    Kuhn, Jana Christine (Doctoral thesis / Doktoravhandling, 2017)
    Childbirth may have a profound impact on maternal circulation. Vaginal delivery exposes the parturient to cardiovascular stress, but the evidence is very limited. Spinal hypotension during caesarean delivery has been studied ...
  • Haemophilia early arthropathy detection with ultrasound and haemophilia joint health score in the moderate haemophilia (MoHem) study 
    Måseide, Ragnhild Johanne; Berntorp, Erik; Astermark, Jan; Hansen, Jessica; Olsson, Anna; Bruzelius, Maria; Frisk, Tony; Aspdahl, Magnus; Nummi, Vuokko; Tjønnfjord, Geir Erland; Holme, Pål Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Introduction Detection of early arthropathy is crucial for the management of haemophilia, but data on moderate haemophilia are limited. Therefore, we evaluated joint health and treatment modalities in Nordic patients ...
  • Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 
    Eilertsen, Helle; Menon, Chaamanti S; Law, Zhe Kang; Chen, Chen; Bath, Philip M; Steiner, Thorsten; Desborough, Michael JR; Sandset, Else Charlotte; Sprigg, Nikola; Al-Shahi Salman, Rustam (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Outcome after acute spontaneous (non‐traumatic) intracerebral haemorrhage (ICH) is influenced by haematoma volume. ICH expansion occurs in about 20% of people with acute ICH. Early haemostatic therapy might ...
  • Hair cortisol and self-perceived stress in adolescents with multi-system functional somatic disorders 
    Nyengaard, Rebecca; Kallesøe, Karen H.; Rimvall, Martin K.; Ørnbøl, Eva; Wellnitz, Kaare B.; Olsen, Else M.; Wyller, Vegard B. B.; Rask, Charlotte U. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
    Background Long-term stress causing altered hypothalamic–pituitary–adrenal (HPA) axis dynamics with cortisol dysfunction may be involved in the pathophysiology of functional somatic disorders (FSD), but ...
  • Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling 
    Merten, Hannes; Brandl, Fabian; Zimmermann, Martina; Schaefer, Jonas V.; Irpinio, Linda; Sand, Kine M.K.; Nilsen, Jeannette; Andersen, Jan Terje; Zangemeister-Wittke, Uwe; Plückthun, Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Serum albumin shows slow clearance from circulation due to neonatal Fc receptor (FcRn)-mediated recycling and has been used for half-life extension. We report here fusions to a high-affinity DARPin, binding to Epithelial ...
  • Hallmarks of postoperative liver regeneration: An updated insight on the regulatory mechanisms 
    Shi, Jihua; Line, Pål Dag (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Performance and advances in liver surgery makes remarkable progress of the understanding of liver regeneration. Liver regeneration after liver resection has been widely researched, and the underlying mechanism mostly ...
  • Hallucinations in healthy older adults: An overview of the literature and perspectives for future research 
    Badcock, Johanna C.; Dehon, Hedwige; Larøi, Frank (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    KEY POINTS Studies suggest a substantial minority of healthy older adults have hallucinatory experiences, in line with existing evidence on hallucinations in other age groups, though it is still unclear if hallucination ...
  • Hallucinations in older adults: A practical review 
    Badcock, Johanna C.; Larøi, Frank; Kamp, Karina; Kelsall-Foreman, India; Bucks, Romola S.; Weinborn, Michael; Begemann, Marieke; Taylor, John-Paul; Collerton, Daniel; O'Brien, John T.; El Haj, Mohamad; Ffytche, Dominic; Sommer, Iris Else Clara (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    By 2050, it is estimated that 16% of people will be aged above 65 years, compared with 9% in 2019.1 Population aging is driving increased attention to the physical and mental health needs of older adults. Here, our focus ...
  • Hallucinations under psychedelics and in the schizophrenia spectrum: An interdisciplinary and multiscale comparison 
    Leptourgos, Pantelis; Fortier-Davy, Martin; Carhart-Harris, Robin; Corlett, Philip; Dupuis, David; Halberstadt, Adam L.; Kometer, Michael; Kozakova, Eva; Larøi, Frank; Noorani, Tehseen N.; Preller, Katrin H.; Waters, Flavie; Zaytseva, Yuliya; Jardri, Renaud (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract The recent renaissance of psychedelic science has reignited interest in the similarity of drug-induced experiences to those more commonly observed in psychiatric contexts such as the schizophrenia-spectrum. This ...
  • Halved contrast medium dose in lower limb dual-energy computed tomography angiography—a randomized controlled trial 
    Kristiansen, Cathrine Helgestad; Thomas, Owen Matthew Truscott; Tran, Thien Trung; Roy, Sumit K; Hykkerud, Dan L; Sanderud, Audun; Geitung, Jonn Terje; Lauritzen, Peter Mæhre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Objectives To compare vascular attenuation (VA) of an experimental half iodine-load dual-layer spectral detector CT (SDCT) lower limb computed tomography angiography (CTA) with control (standard ...
  • Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss 
    Hoff, Mari; Haugeberg, Glenn; Kvien, Tore K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
    The aim of this 2-year longitudinal observational study was to explore hand bone loss as a disease outcome measure in established rheumatoid arthritis (RA). A cohort of 215 patients with RA (170 women and ...
  • Handling realistic assumptions in hypothesis testing of 3D co-localization of genomic elements 
    Paulsen, Jonas; Lien, Tonje G.; Sandve, Geir Kjetil; Holden, Lars; Borgan, Ørnulf; Glad, Ingrid K.; Hovig, Johannes Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    The study of chromatin 3D structure has recently gained much focus owing to novel techniques for detecting genome-wide chromatin contacts using next-generation sequencing. A deeper understanding of the architecture of the ...
  • Hands-free continuous carotid Doppler ultrasound for detection of the pulse during cardiac arrest in a porcine model 
    Faldaas, Bjørn Ove; Nielsen, Erik Waage; Storm, Benjamin; Lappegård, Knut Tore; How, Ole-Jakob; Nilsen, Bent Aksel; Kiss, Gabriel Hanssen; Skogvoll, Eirik; Torp, Hans; Ingul, Charlotte Ingeborg Björk (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background/Purpose Pulse palpation is an unreliable method for diagnosing cardiac arrest. To address this limitation, continuous hemodynamic monitoring may be a viable solution. Therefore, we developed a novel, hands-free ...
  • Haploinsufficiency of two histone modifier genes on 6p22.3, ATXN1 and JARID2, is associated with intellectual disability 
    Barøy, Tuva; Misceo, Doriana; Strømme, Petter; Stray-Pedersen, Asbjørg; Holmgren, Asbjørn; Rødningen, Olaug K; Blomhoff, Anne; Helle, Johan R; Stormyr, Alice; Tvedt, Bjørn; Fannemel, Madeleine; Frengen, Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
  • Haptoglobin 2-2 Genotype, Patient, and Graft Survival in Renal Transplant Recipients 
    Dupont, Laust; Eide, Ivar Anders; Hartmann, Anders; Christensen, Jeppe Hagstrup; Åsberg, Anders; Jenssen, Trond Geir; Krarup, Henrik; Svensson, My Hanna Sofia (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    Background: Cardiovascular disease is the leading cause of death in renal transplant recipients. An association between haptoglobin genotype 2-2 and cardiovascular disease has been found in patients with diabetes mellitus ...
  • Har svangerskapsavbrudd betydning for nedgangen i antall fødsler? 
    Meinich, Tale Jeanette; Eskild, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    BAKGRUNN Fødselsratene i Norge er fallende, og stadig færre får flere enn to barn. Svangerskapsavbrudd kan påvirke fødselstallene. Vi ønsket å studere fordelingen av graviditeter i Norge etter paritet, og om andelen av ...