Browsing Institutt for klinisk medisin by Title
Now showing items 9533-9552 of 10891
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background: Injectable naloxone is already provided as take-home naloxone (THN), and new concentrated intranasal naloxone is now being introduced in Europe. Despite evidence of the effectiveness and cost-effectiveness of ...
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(Master thesis / Masteroppgave, 2012)Denne masteroppgaven handler om hvordan barnevernet oppleves av barn og ungdom som har levd med vold i familien. Oppgaven er basert på kvalitative intervjuer, og temaene som barna har vektlagt er analysert i lys av lovverk ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effective sequencing ...
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Tanker om overlevelse : Flyktningers refleksjoner om styrkende faktorer i et liv med traumehendelser (Master thesis / Masteroppgave, 2012)Flyktninger har som regel en historie som handler om ekstreme påkjenninger, ulike tap, forfølgelse, tvungen migrasjon og en utfordrende eksiltilværelse. Det er kjent at det å bli utsatt for ekstreme hendelser øker sårbarheten ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)The development of immune checkpoint inhibitors represents a major breakthrough in cancer therapy. Nevertheless, a substantial number of patients fail to respond to checkpoint pathway blockade. Evidence for WNT/β-catenin ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)Background: The tapering of methadone or buprenorphine during pregnancy is an understudied and controversial issue. The aim of this study was to determine to what extent women tapered their opioid medication dose during ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)The quantification of illicit drug and pharmaceutical residues in sewage has been shown to be a valuable tool that complements existing approaches in monitoring the patterns and trends of drug use. The present work delineates ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Introduction Systemic sclerosis (SSc) is a heterogenous disorder that appears to result from interplay between vascular pathologies, tissue fibrosis and immune processes, with evidence for deregulation of chemokines, which ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)The serum bone turnover markers (BTM) procollagen type 1 N-terminal propeptide (P1NP) and C-terminal cross-linking telopeptide of type 1 collagen (CTX) are recommended for monitoring adherence and response of antiresorptive ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Relapse of chronic lymphocytic leukaemia and non-Hodgkin’s lymphoma after standard of care treatment is common and new therapies are needed. The targeted alpha therapy with 212Pb-NNV003 presented in this study combines ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Osteosarcoma patients with overt metastases at primary diagnosis have a 5-year survival rate of less than 20%. TP-3 is a murine IgG2b monoclonal antibody with high affinity for an epitope residing on the p80 osteosarcoma ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background & Aims Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are emerging as leading causes of liver disease worldwide. Currently, no specific pharmacologic therapy is available for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Therapeutic idiotypic (Id) vaccination is an experimental treatment for selected B cell malignancies. A broader use of Id-based vaccination, however, is hampered by the complexity and costs due ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background: Idiotypes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-specific T and B cells (antibodies) play a role in immunotherapy of Id+ tumors. However, vaccine strategies that enhance ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2021)Invasive and medical therapy has led to major improvements in cardiovascular disease management, but important challenges remain open. The discovery of a nano-sized system of extracellular vesicles (EVs) is opening new ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background Despite the efforts to describe the molecular landscape of esophageal adenocarcinoma (EAC) and its precursor lesion Barrett’s esophagus (BE), discrepant findings are reported. Here, we investigated ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Hereditary ataxia and spastic paraplegia are heterogeneous monogenic neurodegenerative disorders. To date, a large number of individuals with such disorders remain undiagnosed. Here, we have assessed molecular diagnosis ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background Behavioral and psychological symptoms of dementia (BPSD) occur frequently in people with dementia and can contribute to an increased need for help and a reduced quality of life, but also predict ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Objective To determine the effectiveness of the Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms (TIME) for treatment of moderate to severe agitation in people with dementia. Methods ...
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(Doctoral thesis / Doktoravhandling, 2017)