Browsing Institutt for klinisk medisin by Title

Now showing items 9493-9512 of 10891

  • Systematic literature review of the use of Staff Attitudes to Coercion Scale (SACS) 
    Husum, Tonje Lossius; Siqveland, Johan; Ruud, Torleif; Lickiewicz, Jakub (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objective Staff’s attitudes to the use of coercion may influence the number of coercive interventions employed and staff willingness to engage in professional development projects aimed at reducing the use of coercion ...
  • Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease 
    van der Graaf, Adriaan; Zorro, Maria; Claringbould, Annique; Võsa, Urmo; Aguirre-Gamboa, Raul; Li, Chan; Mooiweer, Joram; Ricaño-Ponce, Isis; Borek, Zuzanna; Koning, Frits; Kooy-Winkelaar, Yvonne; Sollid, Ludvig Magne; Qiao, Shuo Wang; Kumar, Vinod; Li, Yang; Franke, Lude; Withoff, Sebo; Wijmenga, Tjitske Nienke (Cisca); Sanna, Serena; Jonkers, Iris (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Celiac disease (CeD) is a complex T cell-mediated enteropathy induced by gluten. Although genome-wide association studies have identified numerous genomic regions associated with CeD, it is difficult to accurately pinpoint ...
  • Systematic recording and assessment of psychotic symptoms in forensic evaluations of criminal responsibility in Norway 2009-2018 
    Løvgren, Pia Jorde (Doctoral thesis / Doktoravhandling, 2023)
    This thesis analyzes 500 forensic reports regarding criminal responsibility and legal insanity, and is an exploratory, quantitative, registry study of cross-sectional design. Important descriptive information regarding ...
  • Systematic review and meta-analysis of intravascular temperature management vs. surface cooling in comatose patients resuscitated from cardiac arrest. 
    Bartlett, Emily S; Valenzuela, Terence; Idris, Ahamed; Deye, Nicolas; Glover, Guy; Gillies, Michael A.; Taccone, Fabio Silvio; Sunde, Kjetil; Flint, Alexander C; Thiele, Holger; Arrich, Jasmin; Hemphill, Claude; Holzer, Michael; Skrifvars, Markus B.; Pittl, Undine; Polderman, Kees H; Ong, Marcus E H; Kim, Ki Hong; Oh, Sang Hoon; Do Shin, Sang; Kirkegaard, Hans; Nichol, Graham (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Cervids are keystone species in ecosystems and are associated with enormous cultural and economic value. Chronic wasting disease (CWD) is a fatal prion disease spreading in North American cervid populations. The 2016 ...
  • Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences 
    Rowsell, Alison; Sodergren, Samantha C.; Vassiliou, Vassilios; Darlington, Anne-Sophie; Guren, Marianne; Alkhaffaf, Bilal; Moorbey, Chantelle; Dennis, Kristopher; Terada, Mistumi (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract The treatment landscape for gastric cancer (GC) is constantly evolving with therapies affecting all aspects of health-related quality of life (HRQoL) which need careful monitoring. While there are HRQoL measures ...
  • Systematic reviews of observational studies of risk of thrombosis and bleeding in urological surgery (ROTBUS): introduction and methodology 
    Tikkinen, Kari A; Agarwal, Arnav; Craigie, Samantha; Cartwright, Rufus; Gould, Michael K; Haukka, Jari; Naspro, Richard; Novara, Giacomo; Sandset, Per M; Siemieniuk, Reed A; Violette, Philippe D; Guyatt, Gordon H (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background Pharmacological thromboprophylaxis in the peri-operative period involves a trade-off between reduction in venous thromboembolism (VTE) and an increase in bleeding. Baseline risks, in the absence ...
  • Systematic screening for atrial fibrillation in a 65-year-old population with risk factors for stroke: data from the Akershus Cardiac Examination 1950 study 
    Berge, Trygve; Brynhildsen, Jon; Larssen, Hege Netmangen; Onarheim, Sophia; Jenssen, Gaute Reier; Ihle-Hansen, Håkon; Christophersen, Ingrid E.; Myrstad, Marius; Røsjø, Helge; Smith, Pål; Tveit, Arnljot (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Aims To investigate the yield of screening for atrial fibrillation (AF) in a cohort of 65-year-old individuals from the general population with additional risk factors for stroke. Methods and results We invited participants ...
  • The SysteMHC Atlas project 
    Shao, Wenguang; Pedrioli, Patrick G.A.; Wolski, Witold; Scurtescu, Cristian; Schmid, Emanuel; Vizcaíno, Juan Antonio; Courcelles, Mathieu; Schuster, Heiko; Kowalewski, Daniel; Marino, Fabio; Arlehamn, Cecilia S.L.; Vaughan, Kerrie; Peters, Bjoern; Sette, Alessandro; Ottenhoff, Tom H.M.; Meijgaarden, Krista E.; Nieuwenhuizen, Natalie; Kaufmann, Stefan H.E.; Schlapbach, Ralph; Castle, John C.; Nesvizhskii, Alexey I.; Nielsen, Morten; Deutsch, Eric W.; Campbell, David S.; Moritz, Robert L.; Zubarev, Roman A.; Ytterberg, Anders Jimmy; Purcell, Anthony W.; Marcilla, Miguel; Paradela, Alberto; Wang, Qi; Costello, Catherine E.; Ternette, Nicola; van Veelen, Peter A.; van Els, Cécile A.C.M.; Heck, Albert J.R.; De Souza, Gustavo Antonio; Sollid, Ludvig Magne; Admon, Arie; Stevanovic, Stefan; Rammensee, Hans-Georg; Thibault, Pierre; Perreault, Claude; Bassani-Sternberg, Michal; Aebersold, Ruedi; Caron, Etienne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Mass spectrometry (MS)-based immunopeptidomics investigates the repertoire of peptides presented at the cell surface by major histocompatibility complex (MHC) molecules. The broad clinical relevance of MHC-associated ...
  • Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma 
    Enqvist, Monika; Jacobs, Benedikt Marcel; Junlen, Henna R.; Schaffer, Marie; Melen, Christopher Michael; Friberg, Danielle; Wahlin, Björn Engelbrekt; Malmberg, Karl-Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Monotherapy with the anti-CD20 monoclonal antibody rituximab can induce complete responses (CR) in patients with follicular lymphoma (FL). Resting FcRγIII+ (CD16+) natural killer (NK) cells respond strongly to rituximab-coated ...
  • Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis 
    Rødland, Ernst K; Ueland, Thor; Bjørnsen, Stine; Sagen, Ellen L; Dahl, Christen P; Naalsund, Anne; Mollnes, Tom E; Brosstad, Frank R; Müller, Fredrik; Aukrust, Pål; Frøland, Stig S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background The purpose of this study was to investigate mediators of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis (CNPA), a locally, destructive process of the ...
  • Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation 
    Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ...
  • Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients 
    Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne; Holten, Aleksander Rygh; Tonby, Kristian; Barratt-Due, Andreas; Sokolova, Marina; Schjalm, Camilla; Chaban, Viktoriia; Kolderup, Anette; Tran, Trung; Tollefsrud Gjølberg, Torleif; Skeie, Linda Gail; Hesstvedt, Liv; Ormåsen, Vidar; Fevang, Børre; Austad, Cathrine; Muller, Karl Erik; Fladeby, Cathrine; Holberg-Petersen, Mona; Halvorsen, Bente; Müller, Fredrik; Aukrust, Pål; Dudman, Susanne Gjeruldsen; Ueland, Thor; Andersen, Jan Terje; Lund-Johansen, Fridtjof; Heggelund, Lars; Dyrhol-Riise, Anne Ma; Mollnes, Tom Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is hypothesized to be driven by an overreacting innate immune response, where the complement system is a key player. In this prospective ...
  • Systemic exertion intolerance disease diagnostic criteria Applied on an adolescent chronic fatigue syndrom cohort: evaluation of subgroup differences and prognostic utility 
    Asprusten, Tarjei Tørre; Sulheim, Dag; Fagermoen, Frode Even; Winger, Anette; Skovlund, Eva; Wyller, Vegard Bruun Bratholm (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Objective: Existing case definitions for chronic fatigue syndrome (CFS) all have disputed validity. The present study investigates differences between adolescent patients with CFS who satisfy the systemic exertion intolerance ...
  • Systemic immune profile in Prader-Willi syndrome: elevated matrix metalloproteinase and myeloperoxidase and reduced macrophage inhibitory factor 
    Hope, Sigrun; Nærland, Terje; Olav Kolset, Svein; Ueland, Thor; Andreassen, Ole A.; Nordstrøm, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Prader-Willi syndrome (PWS) is a rare genetic neurodevelopmental syndrome with highly increased risk of obesity and cardiovascular disease (CVD). Recent evidence suggests that inflammation is ...
  • Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer 
    Kalanxhi, Ert; Meltzer, Sebastian; Schou, Jakob Vasehus; Larsen, Finn Ole; Dueland, Svein; Flatmark, Kjersti; Jensen, Benny Vittrup; Hole, Knut Håkon; Seierstad, Therese; Redalen, Kathrine; Nielsen, Dorte Lisbet; Ree, Anne Hansen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
  • Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study 
    Heldal, Torbjørn Fossum; Åsberg, Anders; Ueland, Thor; Reisæter, Anna Varberg; Pischke, Soeren; Mollnes, Tom Eirik; Aukrust, Pål; Reinholt, Finn P.; Hartmann, Anders; Heldal, Kristian; Jenssen, Trond (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Early graft loss following kidney transplantation is mainly a result of acute rejection or surgical complications, while long-term kidney allograft loss is more complex. We examined the association between ...
  • Systemic inflammation induced by exacerbation of COPD or pneumonia in patients with COPD induces cardiac troponin elevation 
    Søyseth, Vidar; Kononova, Natalia; Neukamm, Anke; Holmedahl, Nils Henrik; Hagve, Tor-Arne; Omland, Torbjørn; Einvik, Gunnar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Troponin is a biomarker of myocardial injury. In chronic obstructive pulmonary disease (COPD), troponin is an important determinant of mortality after acute exacerbation. Whether acute exacerbation of COPD ...
  • Systemic inflammation persists the first year after mild traumatic brain injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study 
    Chaban, Viktoriia; Clarke, Gerard; Skandsen, Toril; Islam, Rakibul; Einarsen, Cathrine Elisabeth; Vik, Anne; Damås, Jan Kristian; Mollnes, Tom Eirik; Håberg, Asta; Pischke, Soeren (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Innate immune activation has been attributed a key role in traumatic brain injury (TBI) and successive morbidity. In mild TBI (mTBI), however, the extent and persistence of innate immune activation are unknown. We determined ...
  • Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression 
    Jendresen, Charlotte Bille; Digre, Andreas; Cui, Hao; Zhang, Xiao; Vlodavsky, Israel; Li, Jin-Ping; Nilsson, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Amyloid-β (Aβ) is the main constituent of amyloid deposits in Alzheimer’s disease (AD). The neuropathology is associated with neuroinflammation. Here, we investigated effects of systemic lipopolysaccharide (LPS)-treatment ...
  • Systemic lupus erythematosus: Molecular mimicry between anti-dsDNA CDR3 idiotype, microbial and self peptides-as antigens for Th cells 
    Aas-Hanssen, Kristin; Thompson, Keith M; Bogen, Bjarne; Munthe, Ludvig Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Systemic lupus erythematosus (SLE) is marked by a T helper (Th) cell-dependent B cell hyperresponsiveness, with frequent germinal center reactions, and gammaglobulinemia. A feature of SLE is the finding of IgG autoantibodies ...