Browsing Institutt for klinisk medisin by Title

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  • Minimally invasive versus open distal pancreatectomy for pancreatic ductal adenocarcinoma (DIPLOMA): study protocol for a randomized controlled trial 
    van Hilst, Jony; Korrel, Maarten; Lof, Sanne; de Rooij, Thijs; Vissers, Frederique; Al-Sarireh, Bilal; Alseidi, Adnan; Bateman, Adrian C.; Björnsson, Bergthor; Boggi, Ugo; Bratlie, Svein O.; Busch, Olivier; Butturini, Giovanni; Casadei, Riccardo; Dijk, Frederike; Dokmak, Safi; Edwin, Bjorn; van Eijck, Casper; Esposito, Alessandro; Fabre, Jean-Michel; Falconi, Massimo; Ferrari, Giovanni; Fuks, David; Groot Koerkamp, Bas; Hackert, Thilo; Keck, Tobias; Khatkov, Igor; de Kleine, Ruben; Kokkola, Arto; Kooby, David A.; Lips, Daan; Luyer, Misha; Marudanayagam, Ravi; Menon, Krishna; Molenaar, Quintus; de Pastena, Matteo; Pietrabissa, Andrea; Rajak, Rushda; Rosso, Edoardo; Sanchez Velazquez, Patricia; Saint Marc, Olivier; Shah, Mihir; Soonawalla, Zahir; Tomazic, Ales; Verbeke, Caroline; Verheij, Joanne; White, Steven; Wilmink, Hanneke W.; Zerbi, Alessandro; Dijkgraaf, Marcel G.; Besselink, Marc G.; Abu Hilal, Mohammad (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Recently, the first randomized trials comparing minimally invasive distal pancreatectomy (MIDP) with open distal pancreatectomy (ODP) for non-malignant and malignant disease showed a 2-day ...
  • Minimally invasive versus open distal pancreatectomy for resectable pancreatic cancer (DIPLOMA): an international randomised non-inferiority trial 
    Korrel, Maarten; Jones, Leia R.; van Hilst, Jony; Balzano, Gianpaolo; Björnsson, Bergthor; Boggi, Ugo; Bratlie, Svein Olav; Busch, Olivier R.; Butturini, Giovanni; Capretti, Giovanni; Casadei, Riccardo; Edwin, Bjørn von Gohren; Emmen, Anouk M.L.H.; Esposito, Alessandro; Falconi, Massimo; Groot Koerkamp, Bas; Keck, Tobias; de Kleine, Ruben H.J.; Kleive, Dyre; Kokkola, Arto; Lips, Daan J.; Lof, Sanne; Luyer, Misha D.P.; Manzoni, Alberto; Marudanayagam, Ravi; de Pastena, Matteo; Pecorelli, Nicolò; Primrose, John N.; Ricci, Claudio; Salvia, Roberto; Sandström, Per; Vissers, Frederique L.I.M.; Wellner, Ulrich F.; Zerbi, Alessandro; Dijkgraaf, Marcel G.W.; Besselink, Marc G.; Abu Hilal, Mohammad; Tholfsen, Tore; Verbeke, Caroline Sophie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background The oncological safety of minimally invasive surgery has been questioned for several abdominal cancers. Concerns also exist regarding the use of minimally invasive distal pancreatectomy (MIDP) in patients ...
  • Minimum Variance Signal Selection for Aorta Radius Estimation Using Radar 
    Solberg, LarsErik; Hamran, Svein-Erik; Berger, Tor; Balasingham, Ilangko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    This paper studies the optimum signal choice for the estimation of the aortic blood pressure via aorta radius, using a monostatic radar configuration. The method involves developing the Cramér-Rao lower bound (CRLB) for a ...
  • Minor Myocardial Scars in Association with Cardiopulmonary Function after COVID-19 
    Øvrebotten, Tarjei; Heck, Siri Lagethon; Skjørten, Ingunn; Einvik, Gunnar; Stavem, Knut; Ingul, Charlotte Ingeborg Björk; Omland, Torbjørn; Myhre, Peder Langeland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background: Myocardial scars detected by cardiovascular magnetic resonance (CMR) imaging after COVID-19 have caused concerns regarding potential long-term cardiovascular consequences. Objective: The objective of this study ...
  • Minor Surgery for Major Disease - A Randomized Controlled Trial of Laparoscopic and Open Liver Surgery 
    Fretland, Åsmund Avdem (Doctoral thesis / Doktoravhandling, 2020)
    Despite the recent worldwide dissemination of laparoscopic liver surgery, the outcomes of laparoscopic and open liver surgery had never been compared in a randomized controlled trial (RCT). In the thesis “Minor Surgery ...
  • Minute ventilation at different compression to ventilation ratios, different ventilation rates, and continuous chest compressions with asynchronous ventilation in a newborn manikin 
    Solevåg, Anne L; Madland, Jorunn M; Gjærum, Espen; Nakstad, Britt (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background In newborn resuscitation the recommended rate of chest compressions should be 90 per minute and 30 ventilations should be delivered each minute, aiming at achieving a total of 120 events per ...
  • miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy 
    Normann, Lisa Svartdal; Haugen, Mads Haugland; Aure, Miriam Ragle; Kristensen, Vessela N.; Mælandsmo, Gunhild Mari; Sahlberg, Kristine Kleivi (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Purpose: Human epidermal growth factor receptor 2 positive (HER2+) breast cancers responding poorly to targeted therapy need improved treatment options. miR-101-5p has shown tumor-suppressive properties in multiple cancer ...
  • miRAW: A deep learning-based approach to predict microRNA targets by analyzing whole microRNA transcripts 
    Pla, Albert; Zhong, Xiangfu; Rayner, Simon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding to partially complementary regions within the 3’UTR of their target genes. Computational methods play an important role in target ...
  • miRBaseMiner, a tool for investigating miRBase content 
    Zhong, Xiangfu; Heinicke, Fatima; Rayner, Simon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    microRNAs are small non-coding RNA molecules playing a central role in gene regulation. miRBase is the standard reference source for analysis and interpretation of experimental studies. However, the richness and complexity ...
  • MirGeneDB 2.0: the metazoan microRNA complement 
    Fromm, Bastian; Domanska, Diana Ewa; Høye, Eirik; Ovchinnikov, Vladimir; Kang, Wenjing; Aparicio-Puerta, Ernesto; Johansen, Morten; Flatmark, Kjersti; Mathelier, Anthony; Hovig, Eivind; Hackenberg, Michael; Friedländer, Marc R.; Peterson, Kevin J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Small non-coding RNAs have gained substantial attention due to their roles in animal development and human disorders. Among them, microRNAs are special because individual gene sequences are conserved across the animal ...
  • MirGeneDB 2.1: toward a complete sampling of all major animal phyla 
    Fromm, Bastian; Høye, Eirik; Domanska, Diana; Zhong, Xiangfu; Aparicio-Puerta, Ernesto; Ovchinnikov, Vladimir; Umu, Sinan Ugur; Chabot, Peter J; Kang, Wenjing; Aslanzadeh, Morteza; Marmol-Sanchez, Emilio; Urgese, Gianvito; Johansen, Morten; Hovig, Eivind; Hackenberg, Michael; Friedländer, Marc R.; Peterson, Kevin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract We describe an update of MirGeneDB, the manually curated microRNA gene database. Adhering to uniform and consistent criteria for microRNA annotation and nomenclature, we substantially expanded MirGeneDB ...
  • miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer 
    Lindholm, Evita Maria; Aure, Miriam Ragle; Haugen, Mads Haugland; Sahlberg, Kristine Kleivi; Kristensen, Vessela N.; Nebdal, Daniel; Børresen-Dale, Anne-Lise; Lingjærde, Ole Christian; Engebråten, Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    One of the hallmarks of cancer is sustained angiogenesis. Favorable results have been reported in some breast cancer (BC) patients receiving antiangiogenic therapy with bevacizumab (Bev) in combination with chemotherapy, ...
  • miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer 
    Ben-Elazar, Shay; Aure, Miriam Ragle; Jonsdottir, Kristin; Leivonen, Suvi-Katri; Kristensen, Vessela N.; Janssen, Emiel; Sahlberg, Kristine Kleivi; Lingjærde, Ole Christian; Yakhini, Zohar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Different miRNA profiling protocols and technologies introduce differences in the resulting quantitative expression profiles. These include differences in the presence (and measurability) of certain miRNAs. We present and ...
  • Mismatch negativity in schizophrenia spectrum and bipolar disorders: Group and sex differences and associations with symptom severity 
    Pentz, Atle Bråthen; Timpe, Clara Marie Fides; Normann, Elizabeth Marie; Slapø, Nora Berz; Melle, Ingrid; Lagerberg, Trine Vik; Steen, Nils Eiel; Westlye, Lars Tjelta; Jönsson, Erik Gunnar; Haukvik, Unn Kristin Hansen; Moberget, Torgeir; Andreassen, Ole; Elvsåshagen, Torbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objective Research increasingly implicates glutamatergic dysfunction in the pathophysiologies of psychotic disorders. Auditory mismatch negativity (MMN) is an electroencephalography (EEG) waveform linked to glutamatergic ...
  • Misoprostol's preoperative cervical ripening effect 
    Oppegaard, Kevin Sunde (Doctoral thesis / Doktoravhandling, 2009)
    Prostaglandins are recommended for preoperative cervical ripening before surgical abortion, although the ideal dose, route and timing for misoprostol is debated.<br> Prostaglandins appear to be effective for cervical ...
  • Misperception of sleep in bipolar disorder: an exploratory study using questionnaire versus actigraphy 
    Ihler, Henrik M; Meyrel, Manon; Hennion, Vincent; Maruani, Julia; Gross, Gregory; Geoffroy, Pierre A; Lagerberg, Trine V; Melle, Ingrid; Bellivier, Frank; Scott, Jan; Etain, Bruno (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The concept of misperception of sleep refers to the estimated discrepancy between subjective and objective measures of sleep. This has been assessed only in a few prior studies in individuals with Bipolar ...
  • A Missed Summer Wave of the 1918-1919 Influenza Pandemic: Evidence From Household Surveys in the United States and Norway 
    Mamelund, Svenn-Erik; Haneberg, Bjørn; Mjaaland, Siri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background. Reanalysis of influenza survey data from 1918 to 1919 was done to obtain new insights into the geographic and host factors responsible for the various waves. Methods. We analyzed the age- and sex-specific ...
  • Missense mutations in DYT-TOR1A dystonia 
    Iqbal, Zafar; Koht, Jeanette; Pihlstrøm, Lasse; Henriksen, Sandra Pilar; Cappelletti, Chiara; Russell, Michael Bjørn; de Souza, Osmar Norberto; Skogseid, Inger Marie; Toft, Mathias (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    DYT-TOR1A dystonia is caused by dominant mutations in the TOR1A gene, most frequently a heterozygous in-frame deletion in exon 5 (c.904_906delGAG; p.302/303delE).1 The most frequent phenotype has childhood onset in a limb, ...
  • Missing NEIL3: a kick in the gut and a punch to the heart: Mechanisms linking deficiency of the DNA glycosylase NEIL3 to development of atherosclerosis 
    Karlsen, Tom Rune (Doctoral thesis / Doktoravhandling, 2022)
    Cardiovascular disease (CVD), which includes cerebral stroke and myocardial infarction, comprises a significant risk to public health, in addition to being a major financial burden in society. The most important cause ...
  • Misunderstandings in ART Triadic Interactions: A Qualitative Comparison of First and Follow-Up Visits 
    Rossi, Maria Grazia; Vegni, Elena; Menichetti, Julia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Misunderstandings in medical interactions can compromise the quality of communication and affect self-management, especially in complex interactions like those in the assisted reproductive technology (ART) field. ...