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(Master thesis / Masteroppgave, 2017)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
A growing body of evidence suggests that processes of upward treeline expansion and shifts in vegetation zones may occur in response to climate change. However, such shifts can be limited by a variety of non-climatic ...
(Master thesis / Masteroppgave, 2013)
In studies on reproductive ecology of pelagic copepods, the role of males is often neglected and male reproductive investment is not well understood. Lately there has been an increasing interest in the topic and it has ...
(Master thesis / Masteroppgave, 2014)
(Master thesis / Masteroppgave, 2018)
(Master thesis / Masteroppgave, 2019)
Production of autoantibodies by TG2-specific gut plasma cells is a hallmark of celiac disease. Previous studies have revealed biased selection of IGHV and IGKV gene segments, low number of mutations and preferential targeting ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Marine threespine sticklebacks colonized and adapted to brackish and freshwater environments since the last Pleistocene glacial. Throughout the Holarctic, three lateral plate morphs are observed; ...
(Master thesis / Masteroppgave, 2018)
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)
Sperm morphological traits are highly variable among species and are commonly thought to evolve by post-copulatory sexual selection. However, little is known about the evolutionary dynamics of sperm morphology, and whether ...
Protists in the intestinal content of Atlantic cod (Gadus morhua L.), with a special emphasis on two parasite groups; the X-cell and Mesomycetozoa. Restricted Access
(Master thesis / Masteroppgave, 2015)
Protists have representatives in all but one of the kingdoms in the tree of life and are highly important in the oceans, where they generate most of the carbon-flow in the first trophic levels. Parasitic lineages work as ...
(Master thesis / Masteroppgave, 2018)
(Master thesis / Masteroppgave, 2017)
Studies of TRIM21-mediated intracellular virus neutralization Restricted Access
(Master thesis / Masteroppgave, 2015)
(Master thesis / Masteroppgave, 2017)
The sea urchin, Strongylocentrotus droebachiensis, is a prominent grazer in coastal ecosystems with the ability to graze down large areas of kelp forests and turn them into marine deserts, or so called barren grounds. Kelp ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Understanding the effects of habitat modification on the feeding strategies of threatened species is essential to designing effective conservation management plans. Bale monkeys (Chlorocebus ...
Cellular effects of Th-227 Restricted Access
(Master thesis / Masteroppgave, 2014)
CD4+ TH-cell epitope discovery by combinatorial phage display of MHC class II A proof of principle study Restricted Access
(Master thesis / Masteroppgave, 2014)
The interaction between a CD4+ TH cell and an antigen presenting cell (APC) is a finely tuned event in adaptive immunity. The affinity is dictated by the T cell receptor (TCR) and the characteristics of antigenic peptide ...
(Master thesis / Masteroppgave, 2018)
I present a model of chiasma interference and recombination in homo- and heterokaryotypes and a model of nonrandom mating. These two models form the basis of a general-purpose deterministic multilocus evolution simulator, ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Most suids (Mammalia: Suidae, pigs) worldwide are omnivores living in closed environments, but the African warthog (Phacochoerus) has special adaptations for grazing in open environments. Similar specializations have been ...
(Master thesis / Masteroppgave, 2013)
The present study is part of an ongoing effort to monitor the pollution situation in the inner Oslofjord. The purpose of the study was to investigate effects of pollutants on the resident cod population in the area. The ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Signalling proteins often contain several well defined and conserved protein domains. Structural analyses of such domains by nuclear magnetic spectroscopy or X-ray crystallography may greatly inform the function ...
(Master thesis / Masteroppgave, 2020)
The purpose of this study was to find whether exosomes can function as biomarkers for acute leukemia in children, with the long-term goal to assess whether exosomes can be used to predict risk of relapse.
(Master thesis / Masteroppgave, 2020)
(Master thesis / Masteroppgave, 2013)
Speciation involves the evolution of reproductive barriers that maintain the genetic integrity of species. Premating barriers, in particular, have been referred to as one of the most important mechanisms in keeping species ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Forest loss and degradation are the most significant threats to terrestrial biodiversity in the tropics. Promoting flagship or umbrella species is a strategy that can be used to conserve intact forests and restore degraded ...
(Master thesis / Masteroppgave, 2019)
Human activities have historically influenced the evolution of other species. Dramatic modifications in land-use and extreme urbanization have increased not only the amount of species associated with human environments, ...
Understanding the role of RNA binding protein QKI in the regulation of H2A.Z variants in breast cancer Restricted Access
(Master thesis / Masteroppgave, 2020)
Breast cancer is the most predominant form of cancer in females worldwide. High throughput gene expression analysis has led to classification of breast cancer into distinct molecular subtypes (Parker et al., 2009; Perou ...
(Doctoral thesis / Doktoravhandling, 2018)
The genomic landscape of a hybrid species is marked by alternating regions of parental inheritance and areas of genomic constraint which form reproductive barriers.
A PhD candidate at the University of Oslo has explored ...
Structure-function relationship of Shiga toxins; Role of the A-subunit in complex stability and endocytosis Restricted Access
(Master thesis / Masteroppgave, 2014)
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Ongoing climate change threatens biodiversity and directly affects the stability of plant-animal communities. However, it is unclear how the species diversity of biological communities responds to natural climate warming, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Understanding the genetic basis of adaptation is one of the main enigmas of evolutionary biology. Among vertebrates, hemoglobin has been well documented as a key trait for adaptation to different environments. Here, we ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background Functionality of the tetrameric hemoglobin molecule seems to be determined by a few amino acids located in key positions. Oxygen binding encompasses structural changes at the interfaces between the α1β2 and α2β1 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Closely related transcription factors (TFs) can bind to the same response elements (REs) with similar affinities and activate transcription. However, it is unknown whether transcription is similarly orchestrated by different ...
Human IgG subclasses in intracellular antiviral immunity Restricted Access
(Master thesis / Masteroppgave, 2018)
(Master thesis / Masteroppgave, 2019)
The INFLORESCENCE DEFICIENT IN ABSCISSION (IDA)/IDA-LIKE gene family encodes peptides hypothesized to be involved in different cell-separation events in plants. A phylogenetic analysis was performed to elucidate the ...
(Master thesis / Masteroppgave, 2018)
Road and tunnel wash runoff contain a mixture of organic and inorganic contaminants that threatens the quality of natural water bodies, and the health of the organisms dependent on these waters. A variety of treatment ...
An investigation of the functional role of the MADS-box γ and MADS-box α type I transcription factors: AGAMOUS-LIKE 28 and AGAMOUS-LIKE 36 Restricted Access
(Master thesis / Masteroppgave, 2014)
(Master thesis / Masteroppgave, 2019)
microRNAs (miRNAs) are short RNA molecules, which post-transcriptionally regulate other genes. They are generated from genome-encoded single-stranded hairpin structures, by a set of RNA-processing enzymes. miRNAs are highly ...
The role of Gβγ subunits in pertussis toxin amplification of β-adrenoceptor evoked activation of adenylyl cyclase Restricted Access
(Master thesis / Masteroppgave, 2015)
The inhibitory G protein (Gi) has been proposed to participate in β2-adrenergic receptor (β2AR) signaling, but not in β1-adrenergic receptor (β1AR) signaling. Pertussis toxin (PTX) ADP-ribosylates and inhibits Gi, and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
This paper reports a full assessment of results from ICON, an international workshop on marine integrated contaminant monitoring, encompassing different matrices (sediment, fish, mussels, gastropods), areas (Iceland, North ...
In vitro studies of nanosized iron oxide particles Restricted Access
(Master thesis / Masteroppgave, 2013)
Iron oxide nanoparticles are widely used for magnetic resonance imaging, and there is a rapidly expanding research interest in using these nanoparticles for drug delivery or cell labeling. Therefore we need a better ...
(Doctoral thesis / Doktoravhandling, 2013)
Mennesker har i lang tid forvaltet hjortevilt for ulike formål som mat, troféer eller bestandsregulering. Forvaltningen foregår gjennom ulike former for selektiv jakt. Pga. alders- og kjønnsspesifikke kvoter og jegernes ...
Effects of the mycotoxin Deoxynivalenol and grain components on intestinal in vitro model systems Restricted Access
(Master thesis / Masteroppgave, 2019)
Functional Analysis of Stress Signaling in Prostate Cancer Cells Restricted Access
(Master thesis / Masteroppgave, 2016)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Partial migration is common among northern ungulates, typically involving an altitudinal movement for seasonally migratory individuals. The main driving force behind migration is the benefit of an extended period of access ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Postzygotic isolation in the form of reduced viability and/or fertility of hybrids may help maintain species boundaries in the face of interspecific gene flow. Past hybridization events between ...
(Master thesis / Masteroppgave, 2014)
As molecular and bioinformatics techniques are used more frequently and new marine habitats are analysed, a constant increase of marine fungal diversity has been reported, suggesting that marine fungi are a diverse but ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
The ballan wrasse (Labrus bergylta) belongs to a large teleost family containing more than 600 species showing several unique evolutionary traits such as lack of stomach and hermaphroditism. ...
(Master thesis / Masteroppgave, 2014)
There are multiple environmental factors that can affect the toxicity of a chemical to an organism in its natural environment. These include temperature, humidity, predation, competition, diseases, and presence of other ...
(Master thesis / Masteroppgave, 2022)
Cardiovascular disease (CVD) is a major contributor to both mortality and disability worldwide, with numbers of cases continuously rising. While CVD is commonly thought to primarily affect men, it is a main killer amongst ...
(Master thesis / Masteroppgave, 2015)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The importance of forests of the kelp Laminaria hyperborea along the Norwegian coast is related to the three dimensional structure that they create together with the associated macroalgae. Today, kelp forests have recovered ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The Barents Sea system is often depicted as a simple food web in terms of number of dominant feeding links. The most conspicuous feeding link is between the Northeast Arctic cod Gadus morhua, the world's largest cod stock ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Teleosts are exposed to a broad range of external stimuli, which may be either of acute or chronic nature. The larval phase of certain fish species offer a unique opportunity to study the ...
Immune Cell Composition in Human Non-Small Cell Lung Cancer Restricted Access
(Master thesis / Masteroppgave, 2014)
Background: Tumor-infiltrating immune cells analyzed by immunohistochemistry are reported as alternative prognostic factors to supplement TNM staging in operable non-small cell lung cancer (NSCLC), but little is done by ...
(Master thesis / Masteroppgave, 2014)
(Master thesis / Masteroppgave, 2017)
The medial entorhinal cortex (MEC) spatially modulated neurons, including grid cells, all contribute to the brain's spatial navigation system. The mechanisms behind the grid cells' hexagonal firing pattern in space remain ...
Protist diversity across a marine - freshwater gradient with a special focus on the X-cell parasite Restricted Access
(Master thesis / Masteroppgave, 2014)
Protists are a highly abundant and diverse group of microorganisms that hold important ecological roles in all aquatic ecosystems. Phototrophic protists are responsible for a large portion of the global primary production, ...
(Doctoral thesis / Doktoravhandling, 2015)
(Master thesis / Masteroppgave, 2016)
(Master thesis / Masteroppgave, 2014)
In this thesis a bio-optical model was used in order to identify and characterise diversity and fertilisation effects on primary productivity in Freshwaters. The experiments were conducted in mesocosms, comprising 12 ...
Characterization of eIF2α kinases in prostate cancer cells Restricted Access
(Master thesis / Masteroppgave, 2019)
Cancer is the second leading cause of death worldwide. In Norwegian men, prostate cancer (PCa) was the most commonly diagnosed cancer and second most frequent cause of cancer death in 2017. The tumor microenvironment (TME), ...
(Master thesis / Masteroppgave, 2022)
(Master thesis / Masteroppgave, 2014)
(Doctoral thesis / Doktoravhandling, 2018)
Skeletal muscle is a heterogeneous tissue comprised of a variety of different cell types, including the multinucleated skeletal myofiber. Although myofibers are post-mitotic, they hold a remarkable ability to adapt new ...
Genetic and molecular analysis of the functional role of the AGL36 MADS-box Type I transcription factor Restricted Access
(Master thesis / Masteroppgave, 2014)
In angiosperms, seed development is a tightly regulated process often involving different epigenetic mechanisms such as a phenomenon known as imprinting that regulates parental gene expression in a parent-of-origin-dependent ...
(Master thesis / Masteroppgave, 2014)
Juvenile Atlantic cod (Gadus morhua) were exposed to water-accommodated fractions (WAFs) of Arabian light crude oil in two concentrations for one, two or three weeks. The last group was exposed for three weeks followed by ...
(Master thesis / Masteroppgave, 2021)
We exposed the microbiome derived from two species of cod, from the outer and inner Oslo fjord to extracts derived from car tire rubber. To determine toxicity we look at growth rate and bacterial diversity as endpoints. ...
Effekter av miljøgifter på torsk (Gadus morhua) fra indre Oslofjord Restricted Access
(Master thesis / Masteroppgave, 2014)
Utslipp av miljøgifter til miljøet skyldes ofte ulike typer urbane og industrielle aktiviteter. En stor andel av miljøgiftene vil ende opp i akvatiske økosystemer som følge av direkte utslipp eller indirekte utslipp via ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
The class Diphyllatea belongs to a group of enigmatic unicellular eukaryotes that play a key role in reconstructing the morphological innovation and diversification of early eukaryotic evolution. ...
(Master thesis / Masteroppgave, 2019)
Whole exome sequencing was performed to identify putative disease-causing variants in a girl with macrocephaly, epilepsy and severe mental retardation, who had an unknown molecular diagnosis. Compound heterozygous SZT2 ...
(Master thesis / Masteroppgave, 2013)
This thesis examines the phytoplankton diversity in the Oslo Fjord and the seasonality of the size, shape and abundance of the genus Dinophysis Ehrenberg. The genus, which contains several toxin-producing species, has ...
(Master thesis / Masteroppgave, 2013)
Sorghum is ranked the fifth most produced food crop in the world, and is a dietary staple for over 500 million people in over 30 countries. It is the second most produced food crop in Africa, where cultivation of local ...
Characterization of CD276 (B7-H3) in Human Metastatic Melanoma Functions and Interaction Partners Restricted Access
(Master thesis / Masteroppgave, 2015)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Gillnet sampling and analyses of otolith shape, vertebral count and growth indicated the presence of three putative Atlantic herring (Clupea harengus L.) populations mixing together over the spawning season February–June ...
(Master thesis / Masteroppgave, 2014)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Most cervid populations in Europe and North America are managed through selective harvesting, often with age- and sex-specific quotas, with a large influence on the population growth rate. Less well understood is how ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Clostridium botulinum comprises a diverse group of botulinum toxin-producing anaerobic rod-shaped spore-forming bacteria that are ubiquitously distributed in soils and aquatic sediments. Decomposition of plants, algae, and ...
(Master thesis / Masteroppgave, 2014)
Tuberculosis (TB), caused by Mycobacterium tuberculosis, has been treated with the same arsenal of antibiotics since the 1970 s; and with an estimated one third of the world s population latently infected at the moment, ...
(Master thesis / Masteroppgave, 2014)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Next generation sequencing of ribosomal DNA is increasingly used to assess the diversity and structure of microbial communities. Here we test the ability of 454 pyrosequencing to detect the number of species present, and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Rural livelihoods relying on agriculture are particularly vulnerable to climate change. Climate models project increasingly negative effects on maize and sorghum production in sub-Saharan Africa. We present a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background
Plague (Yersinia pestis infection) is a vector-borne disease which caused millions of human deaths in the Middle Ages. The hosts of plague are mostly rodents, and the disease is spread by the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Many wingless ectoparasites have a limited capacity for active movement and are therefore primarily dependent on hitchhiking on their hosts for transportation. The distribution of the tick Ixodes ...
Role of the endolysosomal and autophagosomal pathways in degradation of the gap junction protein connexin 43 Restricted Access
(Master thesis / Masteroppgave, 2014)
(Master thesis / Masteroppgave, 2014)
(Master thesis / Masteroppgave, 2014)
The purpose of this study was to characterise biotransformation and immune responses in juvenile Atlantic cod (Gadus morhua) following exposure for 2, 8 and 16 days to the water-soluble fraction of North Sea crude oil in ...
(Master thesis / Masteroppgave, 2014)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Maize is the most produced crop in Sub-Saharan Africa, but yields are low and climate change is projected to further constrain smallholder production. The current efforts to breed and disseminate new high ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Freshwater fishes of the genus Esox are found throughout the Holarctic region. The northern pike (E. lucius) has a circumpolar distribution whereas the assumed sister species the Amur pike (E. reichertii) is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Ticks and tick-borne diseases are increasing in many areas of Europe and North America due to climate change, while land use and the increased abundances of large hosts play a more controversial role. The pattern ...
(Master thesis / Masteroppgave, 2015)
The tropical Red Sea coast of Saudi Arabia is dominated by intertidal soft sediments, seagrass meadows and mangrove beaches. These habitats have been under high pressure for decades partly due to anthropogenic activity. ...
(Master thesis / Masteroppgave, 2021)
In this study, we assessed the potential synergistic effects of XBP1 and ATF4 on cell growth in two different PCa cell lines. Through simultaneous siRNA-mediated knockdown of ATF4 and total XBP1, we analyzed effects on ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Divergent selection pressures induced by different environmental conditions typically lead to variation in life history, behavior, and morphology. When populations are locally adapted to their current environment, selection ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Salinity is one of the key factors that affects metabolism, survival and distribution of fish species, as all fish osmoregulate and euryhaline fish maintain osmotic differences between their extracellular fluid and either ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The vertical distribution and migration of plankton organisms may have a large impact on their horizontal dispersal and distribution, and consequently on trophic interactions. In this study we used video-net profiling to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
It is generally accepted that the high buoyancy of pelagic marine eggs is due to substantial influx of water across the cell membrane just before ovulation. Here we further develop the theoretical basis by applying laboratory ...