Browsing CRIStin høstingsarkiv by Author "Zaal, Esther A"

Now showing items 1-1 of 1

  • Treatment with HIV-protease inhibitor nelfinavir identifies membrane lipid composition and fluidity as a therapeutic target in advanced multiple myeloma 
    Besse, Lenka; Besse, Andrej; Stolze, Sara C.; Sobh, Amin; Zaal, Esther A; Ham, Alwin J.Van Der; Ruiz, Mario; Phuyal, Santosh; Buchler, Lorina; Sathianathan, Marc; Florea, Bogdan I.; Boren, Jan; Ståhlman, Marcus; Huber, Julia; Bolomsky, Arnold; Ludwig, Heinz; Hannich, J.Thomas; Loguinov, Alex; Everts, Bart; Berkers, Celia R; Pilon, Marc; Farhan, Hesso; Vulpe, Chris D.; Overkleeft, Herman S.; Driessen, Christoph (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The HIV-protease inhibitor nelfinavir has shown broad anticancer activity in various preclinical and clinical contexts. In patients with advanced, proteasome inhibitor (PI)–refractory multiple myeloma, nelfinavir-based ...