Browsing CRIStin høstingsarkiv by Author "Paarmann, Kristin"

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  • Detection and Prediction of Mild Cognitive Impairment in Alzheimer's Disease Mice 
    Rai, Surya Prakash; Bascuñana, Pablo; Brackhan, Mirjam; Krohn, Markus; Möhle, Luisa; Paarmann, Kristin; Pahnke, Jens (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background: The recent failure of clinical trials to treat Alzheimer’s disease (AD) indicates that the current approach of modifying disease is either wrong or is too late to be efficient. Mild cognitive impairment (MCI) ...
  • Generation and characterization of an ABCC1 humanized mouse model (HABCC1<sup>FLX/FLX</sup>) with knockout capability 
    Krohn, Markus; Zoufal, Viktoria; Mairinger, Severin; Wanek, Thomas; Paarmann, Kristin; Brüning, Thomas; Eiriz Delgado, Iván; Brackhan, Mirjam; Langer, Oliver; Pahnke, Jens (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    ATP-binding cassette (ABC) transporters such as ABCB1 (P-glycoprotein), ABCC1 (MRP1), and ABCG2 (BCRP) are well known for their role in rendering cancer cells resistant to chemotherapy. Additionally, recent research provided ...