Browsing Farmasøytisk institutt by Author "Yau, Christina"

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  • RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer 
    Engebraaten, Olav; Yau, Christina; Berg, Kristian; Borgen, Elin; Garred, Øystein; Berstad, Maria E. B.; Fremstedal, Ane S. V.; DeMichele, Angela; Veer, Laura van ’t; Esserman, Laura; Weyergang, Anette (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract HER2 is a predictive biomarker for HER2-targeted therapeutics. For antibody–drug conjugates (ADCs; e.g., trastuzumab emtansine (T-DM1)), HER2 is utilized as a transport gate for cytotoxic agents into the cell. ADC ...