Browsing Farmasøytisk institutt by Author "Wangensteen, Helle"
Now showing items 1-20 of 23
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Hoel, Håvard; de Boer, Hugo; Kool, Anneleen; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)Roots of Gentiana purpurea are known to have an intense bitter taste due to its high content of secoiridoids. In folk medicine roots have commonly been prepared as water decoctions, soaked in ethanol, or boiled with milk, ...
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Gopalakrishnan Saroja, Seethapathy; Tadesse, Margey; Santhosh Kumar, JU; Gunaga, Srikanth V.; Vasudeva, Ramesh; Malterud, Karl Egil; Ramanan, Uma Shaanker; de Boer, Hugo; Gudasalamani, Ravikanth; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Garcinia L. (Clusiaceae) fruits are a rich source of (−)-hydroxycitric acid, and this has gained considerable attention as an anti-obesity agent and a popular weight loss food supplement. In this study, we assessed ...
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Pham, Anh Thu; Nguyen, Celine; Malterud, Karl Egil; Diallo, Drissa; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Three flavone-C-glycosides—cassiaoccidentalin A (1), isovitexin (2) and isoorientin (3)—were isolated from the ethyl acetate (EtOAc) soluble fraction of the methanol crude extract of the African medicinal plant Biophytum ...
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Fu, Yu-ping; Li, Cen-Yu; Zou, Yuanfeng; Peng, Xi; Paulsen, Berit Smestad; Wangensteen, Helle; Inngjerdingen, Kari Tvete (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract BACKGROUND Aconitum carmichaelii is an industrially cultivated medicinal plant in China and its lateral and mother roots are used in traditional Chinese medicine due to the presence of alkaloids. However, the ...
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Ho, Giang Thanh Thi; Kase, Eili Tranheim; Wangensteen, Helle; Barsett, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Type 2 diabetes (T2D) is manifested by progressive metabolic impairments in tissues such as skeletal muscle and liver, and these tissues become less responsive to insulin, leading to hyperglycemia. In the present study, ...
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Ho, Giang Thanh Thi; Wangensteen, Helle; Barsett, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Modulation of complement activity and inhibition of nitric oxide (NO) production by macrophages and dendritic cells may have therapeutic value in inflammatory diseases. Elderberry and elderflower extracts, constituents, ...
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Ho, Giang Thanh Thi; Nguyen, Thi Kim Yen; Kase, Eili Tranheim; Tadesse, Margey; Barsett, Hilde; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)A Western lifestyle with low physical activity and a diet rich in sugar, fat and processed food contribute to higher incidences of diabetes and obesity. Enhanced glucose uptake in human liver cells was observed after ...
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Goodman, Christopher D; Austarheim, Ingvild; Mollard, Vanessa; Mikolo, Bertin; Malterud, Karl E; McFadden, Geoffrey I; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion, 2016)
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Gopalakrishnan Saroja, Seethapathy; Kaliamoorthy, Ravikumar; Paulsen, Berit Smestad; de Boer, Hugo; Wangensteen, Helle (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)Ethnopharmacological relevance: More than 15,000 angiosperm species are dioecious, i.e., having distinct male and female individual plants. The allocation of resources between male and female plants is different, and also ...
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Gopalakrishnan Saroja, Seethapathy; Wold, Christian Winther; Ravikumar, Kaliamoorthy; de Boer, Hugo; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)The resin of Canarium strictum Roxb. is used for rheumatism and asthma; the bark is used as a mosquito repellent. The major compounds in the resin are triterpenoids, but as no studies have been performed on the bark, this ...
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Moussavi, Nastaran; Malterud, Karl E; Mikolo, Bertin; Dawes, Dag; Chandre, Fabrice; Corbel, Vincent; Massamba, Daniel; Overgaard, Hans J; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Zanthoxylum heitzii bark extracts have insecticidal properties and have been reported to be used against malaria in Western Africa. Previously, it has been shown ...
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Moussavi, Nastaran; Azizullah, Hasina; Malterud, Karl Egil; Inngjerdingen, Kari Tvete; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)The herb Sideritis scardica is used in traditional medicine in the Balkan Peninsula. Limited information exists on its health effects, such as improvement of cognitive functions. This study explores the in vitro anti-inflammatory ...
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Overgaard, Hans; Sirisopa, Patcharawan; Mikolo, Bertin; Malterud, Karl Egil; Wangensteen, Helle; Zou, Yuan-Feng; Paulsen, Berit Smestad; Massamba, Daniel; Duchon, Stephane; Corbel, Vincent; Chandre, Fabrice (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)The olon tree, Zanthoxylum heitzii (syn. Fagara heitzii) is commonly found in the central-west African forests. In the Republic of Congo (Congo-Brazzaville) its bark is anecdotally reported to provide human protection ...
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Areta, José; Austarheim, Ingvild; Wangensteen, Helle; Capelli, Carlo (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Introduction: Yerba Mate (YM) is a South American plant, rich in polyphenols, saponins, and xanthines, of growing scientific interest because of its metabolic effects. YM has been shown to increase fat utilization during ...
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Goodman, Christopher D; Austarheim, Ingvild; Mollard, Vanessa; Mikolo, Bertin; Malterud, Karl E; McFadden, Geoffrey I; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Zanthoxylum heitzii (Rutaceae) (olon) is used in traditional medicine in Central and West Africa to treat malaria. To identify novel compounds with anti-parasitic ...
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Fu, Yu-Ping; Li, Cen-Yu; Peng, Xi; Wangensteen, Helle; Inngjerdingen, Kari Tvete; Zou, Yuan-Feng (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)The industrial processing of Aconitum carmichaelii roots for use in Traditional Chinese Medicine generates a high amount of waste material, especially leaves. An acidic polysaccharide fraction isolated from these unutilized ...
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Zhang, Lin; Ulriksen, Emilie Steinbakk; Hoel, Håvard; Sandvik, Lene; Malterud, Karl Egil; Inngjerdingen, Kari Tvete; Inngjerdingen, Marit; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Ethnopharmacological relevance Gentiana purpurea was one of the most important medicinal plants in Norway during the 18th and 19th centuries, and the roots were used against different types of gastrointestinal and airway ...
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Moussavi, Nastaran; Mounkoro, Pakuy Pierre; Dembele, Seydou; Ballo, Ngolo; Togola, Adiaratou; Diallo, Drissa; Sanogo, Rokia; Wangensteen, Helle; Paulsen, Berit Smestad (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)This study explores the traditional knowledge of plants used by traditional health practitioners (THPs) in the treatment of symptoms or syndromes related to mental illnesses in the district of Bamako in Mali, along with ...
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Fu, Yu-Ping; Malterud, Karl Egil; Hamre, Anne Grethe; Inngjerdingen, Kari Tvete; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Aconitum septentrionale is known to contain toxic diterpene alkaloids, while other bioactive compounds in the plant remain unclear. The aim of this study was to explore the phenolic compounds and polysaccharides ...
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Fu, Yu-Ping; Li, Cen-Yu; Peng, Xi; Zou, Yuan-Feng; Rise, Frode; Paulsen, Berit Smestad; Wangensteen, Helle; Inngjerdingen, Kari Tvete (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Roots of Aconitum carmichaelii are used in Asian countries due to its content of bioactive alkaloids. In the production of root preparations, tons of leaves are usually discarded, leading to a huge waste of herbal material. ...