Browsing Farmasøytisk institutt by Title
Now showing items 437-456 of 1934
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Termination of acute inflammation is an active process orchestrated by lipid mediators (LM) derived from polyunsaturated fatty acids, referred to as specialized pro-resolving mediators (SPM). These mediators ...
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(Journal article / Tidsskriftartikkel / PublishedVersion, 2024)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Delirium is a common complication in patients with hip fractures and is associated with an increased risk of subsequent dementia. The aim of this trial was to evaluate the effect of a pre- and postoperative ...
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(Master thesis / Masteroppgave, 2017)
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(Master thesis / Hovedoppgave, 2007)Abstract Background: Aripiprazole is a relatively new antipsychotic drug with a partial dopamine agonist activity. It is metabolized by cytochrome P450 2D6 (CYP2D6) and CYP3A4 to an active metabolite, dehydroaripiprazole. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Aims Atomoxetine is mainly metabolized by CYP2D6 while CYP2C19 plays a secondary role. It is known that patients carrying genotypes encoding decreased/absent CYP2D6 metabolism obtain higher atomoxetine concentrations and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Duloxetine is metabolized by cytochrome P450 (CYP)1A2 and CYP2D6. The aim of this study was to investigate the effect of the CYP2D6 genotype on duloxetine serum concentration adjusting for age and sex. Patients ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Denervation reduces the abundance of Na + ,K + -ATPase (NKA) in skeletal muscle, while reinnervation increases it. Primary human skeletal muscle cells, the most widely used model to study human skeletal muscle in vitro , ...
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(Master thesis / Hovedoppgave, 2006)Introduction: Both risperidone and venlafaxine are metabolized by Cytochrome P450 2D6 (CYP2D6). Genetic polymorphism in this enzyme may contribute to the significant variation in pharmacokinetics for these substances. It ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Introduction Inflammatory joint disease (IJD) is associated with increased risk of cardiovascular disease (CVD) fostered by systemic inflammation and a high prevalence of CVD risk factors. Cardiorespiratory fitness (CRF) ...
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(Master thesis / Hovedoppgave, 2007)2 ABSTRACT Infectious salmon anemia virus (ISAV) is a virus causing severe disease in Atlantic salmon (Salmo salar L.). Although its structure and pathogenesis is well described, little is known about its effects on the ...
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(Master thesis / Hovedoppgave, 2006)3. ABSRTACT Infectious salmon anemia virus (ISAV) is the causative agent of an important viral disease threatening the Atlantic salmon aquaculture in Norway and many other countries. Although its structure and pathogenesis ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Objectives To investigate the effect of integrated medicines management provided to hospitalised multimorbid patients on the quality of drug treatment at discharge measured as the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objective To investigate the effect of pharmacist-led medicines management in multimorbid, hospitalised patients on long-term hospital readmissions and survival. Design Parallel-group, randomised controlled trial. Setting ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)Abstract Background Despite a lack of conclusive evidence of effect, methenamine hippurate is widely prescribed as preventive treatment for recurrent urinary tract infections (UTIs) in ...
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Effect of noradrenaline on propofol-induced mitochondrial dysfunction in human skeletal muscle cells (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background Mitochondrial dysfunction is a hallmark of both critical illness and propofol infusion syndrome and its severity seems to be proportional to the doses of noradrenaline, which patients are ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Objective To investigate the effect of pharmacist-led inhaler technique assessment service on readmissions and CAT-score in hospitalized COPD patients. Furthermore, to provide an effect estimate for sample ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Type 2 diabetes (T2D) is manifested by progressive metabolic impairments in tissues such as skeletal muscle and liver, and these tissues become less responsive to insulin, leading to hyperglycemia. In the present study, ...
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(Master thesis / Masteroppgave, 2012)Malignant melanoma is known as a highly aggressive cancer showing exceptional abilities to metastasize and resist existing therapies. Its incidence worldwide is increasing, having a prognosis of which is hardly to predict. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)4-Methylimidazole (4MeI) is a tremorogenic and convulsive agent of concern both in human and veterinary toxicology. The in vitro effects of 4MeI (5 μM–20 mM) on cerebral glutamate decarboxylase (GAD) activity and (in ...