Browsing Institutt for informatikk by Author "Saadaeijahromi, Hannaneh"

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  • Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis 
    Piplani, Honit; Marek-Iannucci, Stefanie; Sin, Jon; Hou, Jean; Takahashi, Toshimasa; Sharma, Ankush; de Freitas Germano, Juliana; Waldron, Richard T; Saadaeijahromi, Hannaneh; Song, Yang; Gulla, Aiste; Wu, Bechien; Lugea, Aurelia; Andres, Allen M; Gaisano, Herbert Y; Gottlieb, Roberta A; Pandol, Stephen J (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background During pancreatitis, autophagy is activated, but lysosomal degradation of dysfunctional organelles including mitochondria is impaired, resulting in acinar cell death. Retrospective cohort analyses demonstrated ...