Browsing Institutt for informatikk by Author "Olsson, Tomas"

Now showing items 1-5 of 5

  • Ancient genomes from Iceland reveal the making of a human population 
    Ebenesersdóttir, Sigríður Sunna; Sandoval-Velasco, Marcela; Gunnarsdóttir, Ellen D.; Jagadeesan, Anuradha; Guðmundsdóttir, Valdís B.; Thordardóttir, Elísabet L.; Einarsdóttir, Margrét S.; Moore, Kristjan H. S.; Sigurðsson, Ásgeir; Magnúsdóttir, Droplaug N.; Jónsson, Hákon; Snorradóttir, Steinunn; Hovig, Eivind; Møller, Pål; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars; Hansen, Thomas F.; Werge, Thomas; Cavalleri, Gianpiero L.; Gilbert, Edmund; Lalueza-Fox, Carles; Walser III, Joe W.; Kristjánsdóttir, Steinunn; Gopalakrishnan, Shyam; Arnadottir, Lilja; Magnússon, Ólafur Þ.; Gilbert, Marcus Thomas Pius; Stefánsson, Kári; Helgason, Agnar (Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)
    The genomes of ancient humans can reveal patterns of early human migration (see the Perspective by Achilli et al.). Iceland has a genetically distinct population, despite relatively recent settlement (∼1100 years ago). ...
  • Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality 
    Oddsson, Asmundur; Sulem, Patrick; Sveinbjornsson, Gardar; Arnadottir, Gudny A.; Steinthorsdottir, Valgerdur; Halldorsson, Gisli H.; Atlason, Bjarni A.; Oskarsson, Gudjon R.; Helgason, Hannes; Nielsen, Henriette Svarre; Westergaard, David; Karjalainen, Juha; Katrinardottir, Hildigunnur; Fridriksdottir, Run; Jensson, Brynjar O.; Tragante, Vinicius; Ferkingstad, Egil; Jónsson, Hákon; Gudjonsson, Sigurjon A.; Beyter, Doruk; Moore, Kristjan H.S.; Thordardottir, Helga B.; Kristmundsdottir, Snædis; Stefansson, Olafur A.; Rantapää Dahlqvist, Solbritt; Sonderby, Ida Elken; Didriksen, Maria; Stridh, Pernilla; Haavik, Jan; Tryggvadottir, Laufey; Frei, Oleksandr; Walters, G. Bragi; Kockum, Ingrid; Hjalgrim, Henrik; Olafsdottir, Thorunn A; Selbæk, Geir; Nyegaard, Mette; Erikstrup, Christian; Brodersen, Thorsten; Sævarsdottir, Sædis; Olsson, Tomas; Nielsen, Kaspar Rene; Haraldsson, Àsgeir; Bruun, Mie Topholm; Hansen, Thomas Folkmann; Steingrimsdottir, Thora; Jacobsen, Rikke Louise; Lie, Rolv T.; Djurovic, Srdjan; Alfredsson, Lars; Portilla, A.L.; Brunak, Søren; Havdahl, Alexandra; Andreassen, Ole (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Genotypes causing pregnancy loss and perinatal mortality are depleted among living individuals and are therefore difficult to find. To explore genetic causes of recessive lethality, we searched for sequence variants ...
  • Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Saevarsdottir, Saedis; Stefansdottir, Lilja; Sulem, Patrick; Thorleifsson, Gudmar; Ferkingstad, Egil; Rutsdottir, Gudrun; Glintborg, Bente; Westerlind, Helga; Grondal, Gerdur; Loft, Isabella C; Sorensen, Signe Bek; Lie, Benedicte Alexandra; Brink, Mikael; Arlestig, Lisbeth; Arnthorsson, Asgeir Orn; Baecklund, Eva; Banasik, Karina; Bank, Steffen; Bjorkman, Lena I; Ellingsen, Torkell; Erikstrup, Christian; Frei, Oleksandr; Gjertsson, Inger; Gudbjartsson, Daniel F; Gudjonsson, Sigurjon A; Halldorsson, Gisli H; Hendricks, Oliver; Hillert, Jan; Hogdall, Estrid; Jacobsen, Søren; Jensen, Dorte Vendelbo; Jonsson, Helgi Freyr; Kastbom, Alf; Kockum, Ingrid; Kristensen, Salome; Kristjansdottir, Helga; Larsen, Margit H; Linauskas, Asta; Hauge, Ellen-Margrethe; Loft, Anne G; Ludviksson, Bjorn R; Lund, Sigrun H; Markusson, Thorsteinn; Masson, Gisli; Melsted, Pall; Moore, Kristjan H S; Munk, Heidi; Nielsen, Kaspar R; Norddahl, Gudmundur L; Oddsson, Asmundur; Olafsdottir, Thorunn A; Olason, Pall I; Olsson, Tomas; Ostrowski, Sisse Rye; Hørslev-Petersen, Kim; Rognvaldsson, Solvi; Sanner, Helga; Silberberg, Gilad N; Stefansson, Hreinn; Sørensen, Erik; Sørensen, Inge J; Turesson, Carl; Bergman, Thomas; Alfredsson, Lars; Kvien, Tore Kristian; Brunak, Søren; Steinsson, Kristján; Andersen, Vibeke; Andreassen, Ole; Rantapää-Dahlqvist, Solbritt; Hetland, Merete Lund; Klareskog, Lars; Askling, Johan; Padyukov, Leonid; Pedersen, Ole Bv; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Stefansson, Kari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% ...
  • The genetic structure of Norway 
    Mattingsdal, Morten; Ebenesersdóttir, Sigríður Sunna; Moore, Kristjan H. S.; Andreassen, Ole Andreas; Hansen, Thomas F.; Werge, Thomas; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars; Helgason, Agnar; Stefánsson, Kári; Hovig, Johannes Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract The aim of the present study was to describe the genetic structure of the Norwegian population using genotypes from 6369 unrelated individuals with detailed information about places of residence. Using standard ...
  • The population genomic legacy of the second plague pandemic 
    Gopalakrishnan, Shyam; Ebenesersdottir, S.Sunna; Lundstrøm, Inge K.C.; Turner-Walker, Gordon; Moore, Kristjan H.S.; Luisi, Pierre; Magaryan, Ashot; Martin, Michael D.; Ellegaard, Martin Rene; Magnusson, Olafur T.; Sigurdsson, Asgeir; Snorradóttir, Steinunn; Magnúsdóttir, Droplaug N.; Laffoon, Jason E.; van Dorp, Lucy; Liu, Xiaodong; Moltke, Ida; Avila-Arcos, María C.; Schraiber, Joshua G.; Rasmussen, Simon; Juan, David; Galabert, Pere; De-Dios, Toni; Fotakis, Anna K.; Iraeta-Orbegozo, Miren; Vågene, Åshild J.; Denham, Sean Dexter; Christophersen, Axel; Stenøien, Hans K.; Vieira, Filipe G.; Liu, Shanlin; Günther, Torsten; Kivisild, Toomas; Moseng, Ole Georg; Skar, Birgitte; Cheung, Christina; Sandoval-Velasco, Marcela; Wales, Nathan; Schroeder, Hannes; Campos, Paula F.; Gudmundsdottir, Valdis B; Sicheritz - Ponten, Thomas; Petersen, Bent; Halgunset, Jostein; Gilbert, Edmund; Cavalleri, Gianpiero L.; Hovig, Eivind; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars; Hansen, Thomas F.; Werge, Thomas; Willerslev, Eske; Balloux, Francois; Marquès-Bonet, Tomás; Lalueza-Fox, Carles; Nielsen, Rasmus; Stefánsson, Kári; Helgason, Agnar; Gilbert, Thomas P. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned ...