Search
Now showing items 1-100 of 2779
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
Purpose: To identify genes predicting benefit of radiotherapy in patients with high-risk breast cancer treated with systemic therapy and randomized to receive or not receive postmastectomy radiotherapy (PMRT). Experimental ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
This paper studies the effect of mosquito abundance and malaria incidence in the last 3 weeks, and their interaction, on the hazard of time to malaria in a previously studied cohort of children ...
(Doctoral thesis / Doktoravhandling, 2012)
Synaptic transmission requires packing of neurotransmitters into synaptic vesicles. The role of aspartate as a neurotransmitter has been debated for more than 30 years, as vesicular accumulation of aspartate has been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Generalised anxiety disorder (GAD) is a frequent and severe anxiety disorder among older adults. GAD increases the risk of developing other disorders such as depression and coronary heart disease. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Food/drinks available to adolescents in schools can influence their dietary behaviours, which once established in adolescence, tend to remain over time. Food outlets’ influence near schools, known ...
(Doctoral thesis / Doktoravhandling, 2020)
Ischemic heart disease and myocardial infarction increase the risk of fatal heart failure via adverse myocardial remodeling. Cardiac cell death during myocardial infarction results in release of pro-inflammatory factors ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
The role of n-3 polyunsaturated fatty acids (PUFAs) in breast cancer is not clear and under debate. To explore this relationship it is important to have proper validated dietary assessment methods ...
(Doctoral thesis / Doktoravhandling, 2021)
Despite clear health benefits and recommendations, consumption of vegetables in children remains far too low. Although many studies have focused on increasing vegetable intake by children aged up to 5 years, only a few ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
The extent of post-mortem detection of specific psychoactive drugs may differ between countries, and may greatly influence the national death register’s classification of manner and cause of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Replication-independent chromatin deposition of histone variant H3.3 is mediated by several chaperones. We report a multistep targeting of newly synthesized epitope-tagged H3.3 to chromatin via PML bodies. H3.3 is recruited ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
To examine whether delirium in hip fracture patients was associated with changes in the levels of amino acids and/or monoamine metabolites in cerebrospinal fluid (CSF) and serum.
...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. ...
(Doctoral thesis / Doktoravhandling, 2018)
Apotek velegnet for testing av hjerte-kar-risiko
Viktige risikofaktorer for hjerte- og karsykdommer, som høyt kolesterol, høyt blodtrykk og høyt blodsukker, gir sjeldent symptomer. Man må derfor sjekke seg for å vite sin ...
(Doctoral thesis / Doktoravhandling, 2021)
Organ donor shortage is a global problem, and patients die every day waiting for a transplant. In the field of tissue engineering, a major aim is to grow functional organs and tissues in the lab. Often using the patient’s ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
We investigate the effect of measurement error on principal component analysis in the high‐dimensional setting. The effects of random, additive errors are characterized by the expectation and variance of the changes in the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
People with deliberate self-poisoning and personality disorders are in increased risk for suicide. Intention and psychiatric features are important factors in a psychiatric evaluation and for ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2009)
(Book / Bok / PublishedVersion; Peer reviewed, 1999)
(Master thesis / Masteroppgave, 2008)
It is well established that exercise protect againsts chronic disorders such as cardiovascular diseases (CVD), type 2 diabetes (DM2), dementia and depression. It is unclear how contracting skeletal muscles mediate metabolic ...
(Doctoral thesis / Doktoravhandling, 2009)
Liver X Receptor og genregulering i morkaken (placenta).<br>
Cand. Scient. Susanne Weedon-Fekjær har i sin doktorgrad studert rollene til transkripsjonsfaktorene Liver X Receptors (LXR) i morkake og morkakeceller hos ...
(Doctoral thesis / Doktoravhandling, 2013)
(Master thesis / Masteroppgave, 2012)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Objective: Investigate whether gastroenterologists rate the quality of referral letters higher if electronic dynamic checklist items are added to a standard free-text referral letter. Assess how this affects the ...
Role of LSDP5 i diet induced obese and insulin resistant mice Restricted Access
(Master thesis / Masteroppgave, 2008)
(Doctoral thesis / Doktoravhandling, 2007)
TIDLIG OPPDAGELSE OG BEHANDLING AV PSYKOSELIDELSER (TIPS)
Evidence-based, kunnskapsbasert, vitenbasert utvikling av helsetjenestene generelt, og av psykiatrihelsetjenestene spesielt, er sjeldnere enn vi liker å tro.
Utformingen ...
(Doctoral thesis / Doktoravhandling, 2008)
Signalmolekylene i hjernen kan enten stimulere eller hemme nabocellene. Det viktigste stimulerende signalmolekylet er glutamat. Holten og medarbeidere legger i denne avhandlingen fram data som bekrefter at også aspartat ...
(Master thesis / Masteroppgave, 2011)
Objectives: The main aim of this longitudinal study was to describe dietary behaviors and Body Mass Index (BMI) in an adolescent cohort from age 15 to age 18 in Oslo, Norway. There were three sub-questions: ‡@ To what ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Organotypic cultures from the ventral mesencephalon (VM) are widely used to model Parkinson’s disease (PD). In this method, neurotoxic compounds have traditionally been applied to the media to induce a uniform dopaminergic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Metabotyping is a novel concept to group metabolically similar individuals. Different metabotypes may respond differently to dietary interventions; hence, metabotyping may become an important ...
(Doctoral thesis / Doktoravhandling, 2018)
There is a global epidemic of obesity in children, partly because of unhealthy diets. Taste preferences are part of the foundation for diets, but have not previously been longitudinally investigated in preschoolers. This ...
(Doctoral thesis / Doktoravhandling, 2018)
Natural killer (NK) cells recognize and kill cancer cells and infected cells. How NK cells discriminate between cancer cells and normal cells is not fully known. In this thesis we have found that an activating receptor ...
(Doctoral thesis / Doktoravhandling, 2016)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Tumor size, as indicated by the T-category, is known as a strong prognostic indicator for breast cancer. It is common practice to distinguish the T1 and T2 groups at a tumor size of 2.0 cm. We investigated the 2.0-cm rule ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Completing upper secondary education is associated with higher work participation and less health-related absence from work. Although these outcomes are closely interrelated, most studies focus ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)
Taurine is regarded as an essential amino acid in utero, and fetal taurine supply is believed to rely solely on placental transfer from maternal plasma. Despite its potential role in intrauterine growth restriction and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
When measuring a range of genomic, epigenomic, and transcriptomic variables for the same tissue sample, an integrative approach to analysis can strengthen inference and lead to new insights. This is also the case when ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The most recent systematic literature reviews and meta-analyses have indicated significant and nutritionally-relevant composition differences between organic and conventional foods. This included higher antioxidant, but ...
(Doctoral thesis / Doktoravhandling, 2018)
Birth asphyxia can lead to hypoxic-ischaemic (HI) brain injury. A concomitant perinatal infection increases the risk of neurological sequelae. Hypothermia treatment (HT) is current standard treatment for birth asphyxia. ...
(Doctoral thesis / Doktoravhandling, 2019)
This thesis develops and exploits methodology within network science, driven by important applications. By use of large-scale simulations and high-quality data, we demonstrate how network science can contribute to understanding ...
(Doctoral thesis / Doktoravhandling, 2008)
Neurons conduct electrical signals, and signals pass from one neuron to the next by the use of chemical substances in specialized contacts, synapses. In most synapses, the transmitter is the amino acid glutamate. <br>
A ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
National guidelines emphasize healthy eating to promote wellbeing and prevention of non-communicable diseases. The perceived healthiness of food is determined by many factors affecting food ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Atlases of the rat brain are widely used as reference for orientation, planning of experiments, and as tools for assigning location to experimental data. Improved quality and use of magnetic resonance imaging (MRI) and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Nutrigenetic research examines the effects of inter-individual differences in genotype on responses to nutrients and other food components, in the context of health and of nutrient requirements. A practical application of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Beyond survival of nowadays >80%, modern childhood cancer treatment strives to preserve long-term health and quality of life. However, the majority of today’s survivors suffer from short- and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
To validate estimated intakes of carotenoid-rich foods from a web-based food recall (WebFR) using carotenoids in blood as an objective reference method.
Cross-sectional validation study using carotenoids in plasma to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
A wide range of diseases show some degree of clustering in families; family history is therefore an important aspect for clinicians when making risk predictions. Familial aggregation is often ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
The phenotypic stability of mixed connective tissue disease (MCTD) is not clear, and knowledge about disease activity and remission is scarce. We aimed to establish the occurrence of evolution ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Long-term impact of intrauterine fetal death on quality of life and depression: a case–control study
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Background
Intrauterine fetal death (IUFD) is a serious incidence that has been shown to impact mothers’ psychological well-being in the short-term. Long-term quality of life (QOL) and depression after IUFD ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Signalling proteins often contain several well defined and conserved protein domains. Structural analyses of such domains by nuclear magnetic spectroscopy or X-ray crystallography may greatly inform the function ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Objectives: (1) To investigate the experiences of women with a previous stillbirth and their appraisal of the care they received at the hospital. (2) To assess the long-term level of post-traumatic stress symptoms (PTSS) ...
(Doctoral thesis / Doktoravhandling, 2010)
Over the past decades many western countries have witnessed an epidemic rise in obesity, insulin resistance and type 2 diabetes. There clearly is a link between increased fat storage and decreased insulin sensitivity leading ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Diet has a great impact on the risk of developing features of metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiovascular diseases (CVD). We evaluated whether a long-term ...
(Master thesis / Masteroppgave, 2009)
Regular physical activity has beneficial effects on health. The relations between exercise and health are not fully understood. Myokines are secretory peptides of skeletal muscle origin with auto-, para- or endocrine ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background Recent studies suggest that lactation has long-term effects on risk for cardiovascular disease in women, but the effects on cardiovascular mortality are less well known. Method In a Norwegian population-based ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Objective: Examine responses given to questions addressing whether pregnancy had caused women with nausea and vomiting (NVP) or symptom-free (SF) to alter their food habits in the first trimester in order to better understand ...
(Doctoral thesis / Doktoravhandling, 2018)
På samme måte som søppel dannes fra vårt daglige forbruk, produserer cellene i kroppen vår avfallsprodukter som transporteres til cellens resykleringsstasjon (lysosomet), hvor det brytes ned og gjenvinnes. Dette skjer via ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The purpose of this study was to validate estimated energy intake from a web-based food recall, designed for children and adolescents. We directly compared energy intake to estimates of total energy expenditure, calculated ...
(Doctoral thesis / Doktoravhandling, 2008)
I fire vitenskaplige arbeider, har vi studert data fra det Norske mammografi programmet (brystkreft screening programmet), med moderne statistiske metoder og kraftige datamaskiner. I det første arbeidet ser vi at risikoen ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Intercellular communication is pivotal in optimizing and synchronizing cellular responses to keep homeostasis and to respond adequately to external stimuli. In the central nervous system (CNS), glutamatergic and GABAergic ...
(Doctoral thesis / Doktoravhandling, 2007)
Chronic fatigue syndrome (CFS) is a disabling disease with unknown pathophysiology, but recent evidence suggests autonomic dysfunction. We have therefore explored cardiovascular and thermoregulatory autonomic responses. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
More than 14 % of Ugandan children are orphaned and many live in children’s homes. Ugandan authorities have targeted adolescent girls as a priority group for nutrition interventions as safeguarding ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Fish consumption may prevent or improve metabolic health. The aim of this study was to identify associations between fish consumption, both fatty and lean, and metabolic syndrome and its ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Early adulthood is a period associated with poor diet and rapid weight gain. This is also an age of transition, including environmental, social and lifestyle changes which may be associated with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background
Policy frameworks focusing on policy implementation may vary in terms of their scope, included constructs, relationships between the constructs, and context factors. Although multiple policy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Doctor –certified sick leave is prevalent in the health and social sector. We examined whether the higher risk of doctor-certified sick leave in women in health and social occupations compared ...
(Doctoral thesis / Doktoravhandling, 2016)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Fish consumption may have a role in reducing the prevalence of metabolic syndrome (MetS). The aim of this study was to identify associations between fish consumption and MetS and its components, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Understanding the determinants associated with prediabetes and type 2 diabetes in coronary patients may help to individualize treatment and modelling interventions. We sought to identify ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
The endovascular treatment procedure in tandem occlusions (TO) is complex compared to single occlusion (SO) and optimal management remains uncertain. The aim of this study was to identify clinical ...
(Doctoral thesis / Doktoravhandling, 2016)
GABA and glutamate transporter proteins are important in relation to epilepsy because they represent the mechanisms that keep the extracellular concentrations of GABA and dicarboxylic amino acids low. GABA and glutamate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Multi-item rating scales for depression informs about the level of depression, but does not allow individuals to state by self-evaluation whether they feel depressed or not. The insider perspective ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The comet assay has developed over the past 30 years and today, a variety of different DNA lesions and DNA repair can be measured by different versions of the assay (Collins, 2004). In the final step of the method, an image ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
This is a six-year prospective follow-up of a former cross sectional study of suicide attempters in a sample of treatment-seeking substance-dependent patients. The aims were to explore the frequency ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
Communication training builds on the assumption that understanding of the concepts related to professional communication facilitates the training. We know little about whether students' knowledge ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Self-evaluations of mental health problems may be a useful complement to diagnostic assessment, but are less frequently used. This study investigated the prevalence of self-evaluated current and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
There is a lack of comprehensive patient-datasets regarding prevalence of severe hypertriglyceridemia (sHTG; triglycerides ≥10 mmol/L), frequency of co-morbidities, gene mutations, and gene ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Vaccines using dendritic cells (DCs) harboring leukemic antigens to stimulate T cells is a possible treatment of acute myeloid leukemia (AML). Limitations of breaking tolerance to leukemic cells and lack of specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Aquaporin-4 (AQP4) water channels are concentrated in astrocytic endfoot membranes at the brain–blood and brain–cerebrospinal fluid interfaces. The mechanisms underpinning the polarized distribution of AQP4 are poorly ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Rheumatoid arthritis (RA) is a long-term disease that leads to inflammation of the joints and surrounding tissues. Natural killer(NK) cells are an important part of the innate immune system and are responsible for the first ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: There is a need for valid and comprehensive measures of parental influence on children’s energy balance-related behaviours (EBRB). Such measures should be based on a theoretical framework, acknowledging the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Background: Polychlorinated biphenyls (PCBs) are a class of organic compounds that bioaccumulate due to their chemical stability and lipophilic properties. Humans are prenatally exposed via trans-placental transfer, through ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The T cell specific adapter protein (TSAd) is expressed in activated T cells and NK cells. While TSAd is beginning to emerge as a critical regulator of Lck and Itk activity in T cells, its role in NK cells has not yet been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Nondirective meditation techniques are practiced with a relaxed focus of attention that permits spontaneously occurring thoughts, images, sensations, memories, and emotions to emerge and pass freely, without any expectation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
The process of radiationless energy transfer from a chromophore in an excited electronic state (the donor ) to another chromophore (an acceptor ), in which the energy released by the donor effects an electronic transition, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Using high-dimensional penalized regression we studied genome-wide DNA-methylation in bone biopsies of 80 postmenopausal women in relation to their bone mineral density (BMD). The women showed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Lipids through regulation of chronic inflammation play key roles in the development of various diseases. Here, we report that a mixed population of human primary monocytes migrated towards LPC, as well as oxidized linoleic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Objective To compare cognitive function in adolescents with chronic fatigue with cognitive function in healthy controls (HC).
Study design Cross-sectional study.
Setting Paediatric department at Oslo University Hospital, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Young patients with acute poisoning by substances of abuse have increased mortality rates in the long term. In Oslo, Norway, most of these patients are treated at the Oslo Accident and Emergency ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
In the comet assay single cells are analyzed with respect to their level of DNA damage. Discrimination of the individual cell or cell type based on DNA content, with concomitant scoring of the DNA damage, is useful since ...
(Doctoral thesis / Doktoravhandling, 2018)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Objective
Earlier studies documenting the effect of candidate genes on recovery have seldom taken into consideration the impact of emotional distress. Thus, we aimed to assess the modifying effect of emotional ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
To explore contemporary (from 1990) utilization and practice of electroconvulsive therapy (ECT) worldwide. Systematic search (limited to studies published 1990 and after) was undertaken in the databases Medline, Embase, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
RNA interference (RNAi) has become an invaluable tool for functional genomics. A critical use of this tool depends on an understanding of the factors that determine the specificity and activity of the active agent, small ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Patients’ knowledge about psoriasis and its treatment has been randomly studied previously. The aim of the study is to investigate patients’ knowledge about psoriasis in relation to undergoing patient education in the ...