Browsing Institutt for medisinske basalfag by Title

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  • [18F]-Flutemetamol Uptake in Cortex and White Matter: Comparison with Cerebrospinal Fluid Biomarkers and [18F]-Fludeoxyglucose 
    Kalheim, Lisa Flem; Fladby, Tormod; Coello, Christopher; Bjørnerud, Atle; Selnes, Per (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Flutemetamol (18F-Flut) is an [18F]-labelled amyloid PET tracer with increasing availability. The main objectives of this study were to investigate 1) cerebrospinal fluid (CSF) Aβ 1-42 (Aβ42) concentrations associated with ...
  • 2.5-fold increased risk of recurrent acute myocardial infarction with familial hypercholesterolemia 
    Svendsen, Karianne; Krogh, Henriette Walaas; Igland, Jannicke; Tell, Grethe S.; Mundal, Liv J.; Holven, Kirsten Bjørklund; Bogsrud, Martin P.; Leren, Trond P.; Retterstøl, Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background and aims A first-time acute myocardial infarction (AMI) is a severe diagnosis that leads to initiation or intensification of lipid-lowering medication to prevent recurrent events. Individuals with familial ...
  • 26th Annual Computational Neuroscience Meeting (CNS*2017): Part 2 
    Rubchinsky, Leonid L; Ahn, Sungwoo; Klijn, Wouter; Cumming, Ben; Yates, Stuart; Karakasis, Vasileios; Peyser, Alexander; Woodman, Marmaduke; Diaz-Pier, Sandra; Deraeve, James; Vassena, Eliana; Alexander, William; Beeman, David; Kudela, Pawel; Boatman-Reich, Dana; Anderson, William S; Luque, Niceto R; Naveros, Francisco; Carrillo, Richard R; Ros, Eduardo; Arleo, Angelo; Huth, Jacob; Ichinose, Koki; Park, Jihoon; Kawai, Yuji; Suzuki, Junichi; Mori, Hiroki; Asada, Minoru; Oprisan, Sorinel A; Dave, Austin I; Babaie, Tahereh; Robinson, Peter; Tabas, Alejandro; Andermann, Martin; Rupp, André; Balaguer-Ballester, Emili; Lindén, Henrik; Christensen, Rasmus K; Nakamura, Mari; Barkat, Tania R; Tosi, Zach; Beggs, John; Lonardoni, Davide; Boi, Fabio; Di Marco, Stefano; Maccione, Alessandro; Berdondini, Luca; Jędrzejewska-Szmek, Joanna; Dorman, Daniel B; Blackwell, Kim T; Bauermeister, Christoph; Keren, Hanna; Braun, Jochen; Dornas, João V; Mavritsaki, Eirini; Aldrovandi, Silvio; Bridger, Emma; Lim, Sukbin; Brunel, Nicolas; Buchin, Anatoly; Kerr, Clifford C; Chizhov, Anton; Huberfeld, Gilles; Miles, Richard; Gutkin, Boris; Spencer, Martin J; Meffin, Hamish; Grayden, David B; Burkitt, Anthony N; Davey, Catherine E; Tao, Liangyu; Tiruvadi, Vineet; Ali, Rehman; Mayberg, Helen; Butera, Robert; Gunay, Cengiz; Lamb, Damon; Calabrese, Ronald L; Doloc-Mihu, Anca; López-Madrona, Víctor J; Matias, Fernanda S; Pereda, Ernesto; Mirasso, Claudio R; Canals, Santiago; Geminiani, Alice; Pedrocchi, Alessandra; D’Angelo, Egidio; Casellato, Claudia; Chauhan, Ankur; Soman, Karthik; Srinivasa Chakravarthy, V.; Muddapu, Vignayanandam R; Chuang, Chao-Chun; Chen, Nan-yow; Bayati, Mehdi; Melchior, Jan; Wiskott, Laurenz; Azizi, Amir H; Diba, Kamran; Cheng, Sen; Smirnova, Elena Y; Yakimova, Elena G; Chizhov, Anton V; Chen, Nan-Yow; Shih, Chi-Tin; Florescu, Dorian; Coca, Daniel; Courtiol, Julie; Jirsa, Viktor K; Covolan, Roberto J M; Teleńczuk, Bartosz; Kempter, Richard; Curio, Gabriel; Destexhe, Alain; Parker, Jessica; Klishko, Alexander N; Prilutsky, Boris I; Cymbalyuk, Gennady; Franke, Felix; Hierlemann, Andreas; da Silveira, Rava A; Casali, Stefano; Masoli, Stefano; Rizza, Martina; Rizza, Martina F; Masoli, Stefano; Sun, Yinming; Wong, Willy; Farzan, Faranak; Blumberger, Daniel M; Daskalakis, Zafiris J; Popovych, Svitlana; Viswanathan, Shivakumar; Rosjat, Nils; Grefkes, Christian; Daun, Silvia; Gentiletti, Damiano; Suffczynski, Piotr; Gnatkovski, Vadym; De Curtis, Marco; Lee, Hyeonsu; Paik, Se-Bum; Choi, Woochul; Jang, Jaeson; Park, Youngjin; Song, Jun H; Song, Min; Pallarés, Vicente; Gilson, Matthieu; Kühn, Simone; Insabato, Andrea; Deco, Gustavo; Glomb, Katharina; Ponce-Alvarez, Adrián; Ritter, Petra; Gilson, Matthieu; Campo, Adria T; Thiele, Alexander; Deeba, Farah; Robinson, P. A; van Albada, Sacha J; Rowley, Andrew; Hopkins, Michael; Schmidt, Maximilian; Stokes, Alan B; Lester, David R; Furber, Steve; Diesmann, Markus; Barri, Alessandro; Wiechert, Martin T; DiGregorio, David A; Dimitrov, Alexander G; Vich, Catalina; Berg, Rune W; Guillamon, Antoni; Ditlevsen, Susanne; Cazé, Romain D; Girard, Benoît; Doncieux, Stéphane; Doyon, Nicolas; Boahen, Frank; Desrosiers, Patrick; Laurence, Edward; Doyon, Nicolas; Dubé, Louis J; Eleonora, Russo; Durstewitz, Daniel; Schmidt, Dominik; Mäki-Marttunen, Tuomo; Krull, Florian; Bettella, Francesco; Metzner, Christoph; Devor, Anna; Djurovic, Srdjan; Dale, Anders M; Andreassen, Ole A; Einevoll, Gaute T; Næss, Solveig; Ness, Torbjørn V; Halnes, Geir; Halgren, Eric; Halnes, Geir; Mäki-Marttunen, Tuomo; Pettersen, Klas H; Andreassen, Ole A; Sætra, Marte J; Hagen, Espen; Schiffer, Alina; Grzymisch, Axel; Persike, Malte; Ernst, Udo; Harnack, Daniel; Ernst, Udo A; Tomen, Nergis; Zucca, Stefano; Pasquale, Valentina; Pica, Giuseppe; Molano-Mazón, Manuel; Chiappalone, Michela; Panzeri, Stefano; Fellin, Tommaso; Oie, Kelvin S; Boothe, David L; Crone, Joshua C; Yu, Alfred B; Felton, Melvin A; Zulfiqar, Isma; Moerel, Michelle; De Weerd, Peter; Formisano, Elia; Boothe, David L; Crone, Joshua C; Felton, Melvin A; Oie, Kelvin; Franaszczuk, Piotr; Diggelmann, Roland; Fiscella, Michele; Hierlemann, Andreas; Franke, Felix; Guarino, Domenico; Antolík, Jan; Davison, Andrew P; Frègnac, Yves; Etienne, Benjamin X; Frohlich, Flavio; Lefebvre, Jérémie; Marcos, Encarni; Mattia, Maurizio; Genovesio, Aldo; Fedorov, Leonid A; Dijkstra, Tjeerd M; Sting, Louisa; Hock, Howard; Giese, Martin A; Buhry, Laure; Langlet, Clément; Giovannini, Francesco; Verbist, Christophe; Salvadé, Stefano; Giugliano, Michele; Henderson, James A; Wernecke, Hendrik; Sándor, Bulcsú; Gros, Claudius; Voges, Nicole; Dabrovska, Paulina; Riehle, Alexa; Brochier, Thomas; Grün, Sonja; Gu, Yifan; Gong, Pulin; Dumont, Grégory; Novikov, Nikita A; Gutkin, Boris S; Tewatia, Parul; Eriksson, Olivia; Kramer, Andrei; Santos, Joao; Jauhiainen, Alexandra; Kotaleski, Jeanette H; Belić, Jovana J; Kumar, Arvind; Kotaleski, Jeanette H; Shimono, Masanori; Hatano, Naomichi; Ahmad, Subutai; Cui, Yuwei; Hawkins, Jeff; Senk, Johanna; Korvasová, Karolína; Tetzlaff, Tom; Helias, Moritz; Kühn, Tobias; Denker, Michael; Mana, PierGianLuca; Grün, Sonja; Dahmen, David; Schuecker, Jannis; Goedeke, Sven; Keup, Christian; Goedeke, Sven; Heuer, Katja; Bakker, Rembrandt; Tiesinga, Paul; Toro, Roberto; Qin, Wei; Hadjinicolaou, Alex; Grayden, David B; Ibbotson, Michael R; Kameneva, Tatiana; Lytton, William W; Mulugeta, Lealem; Drach, Andrew; Myers, Jerry G; Horner, Marc; Vadigepalli, Rajanikanth; Morrison, Tina; Walton, Marlei; Steele, Martin; Anthony Hunt, C.; Tam, Nicoladie; Amaducci, Rodrigo; Muñiz, Carlos; Reyes-Sánchez, Manuel; Rodríguez, Francisco B; Varona, Pablo; Cronin, Joseph T; Hennig, Matthias H; Iavarone, Elisabetta; Yi, Jane; Shi, Ying; Zandt, Bas-Jan; Van Geit, Werner; Rössert, Christian; Markram, Henry; Hill, Sean; O’Reilly, Christian; Iavarone, Elisabetta; Shi, Ying; Perin, Rodrigo; Lu, Huanxiang; Zandt, Bas-Jan; Bryson, Alexander; Rössert, Christian; Hadrava, Michal; Hlinka, Jaroslav; Hosaka, Ryosuke; Olenik, Mark; Houghton, Conor; Iannella, Nicolangelo; Launey, Thomas; Kameneva, Tatiana; Kotsakidis, Rebecca; Meffin, Hamish; Soriano, Jaymar; Kubo, Takatomi; Inoue, Takao; Kida, Hiroyuki; Yamakawa, Toshitaka; Suzuki, Michiyasu; Ikeda, Kazushi; Abbasi, Samira; Hudson, Amber E; Heck, Detlef H; Jaeger, Dieter; Lee, Joel; Abbasi, Samira; Janušonis, Skirmantas; Saggio, Maria L; Spiegler, Andreas; Stacey, William C; Bernard, Christophe; Lillo, Davide; Bernard, Christophe; Petkoski, Spase; Spiegler, Andreas; Drakesmith, Mark; Jones, Derek K; Zadeh, Ali S; Kambhampati, Chandra; Karbowski, Jan; Kaya, Zeynep G; Lakretz, Yair; Treves, Alessandro; Li, Lily W; Lizier, Joseph; Kerr, Cliff C; Masquelier, Timothée; Kheradpisheh, Saeed R; Kim, Hojeong; Kim, Chang S; Marakshina, Julia A; Vartanov, Alexander V; Neklyudova, Anastasia A; Kozlovskiy, Stanislav A; Kiselnikov, Andrey A; Taniguchi, Kanako; Kitano, Katsunori; Schmitt, Oliver; Lessmann, Felix; Schwanke, Sebastian; Eipert, Peter; Meinhardt, Jennifer; Beier, Julia; Kadir, Kanar; Karnitzki, Adrian; Sellner, Linda; Klünker, Ann-Christin; Kuch, Lena; Ruß, Frauke; Jenssen, Jörg; Wree, Andreas; Sanz-Leon, Paula; Knock, Stuart A; Chien, Shih-Cheng; Maess, Burkhard; Knösche, Thomas R; Cohen, Charles C; Popovic, Marko A; Klooster, Jan; Kole, Maarten H; Roberts, Erik A; Kopell, Nancy J; Kepple, Daniel; Giaffar, Hamza; Rinberg, Dima; Koulakov, Alex; Forlim, Caroline G; Klock, Leonie; Bächle, Johanna; Stoll, Laura; Giemsa, Patrick; Fuchs, Marie; Schoofs, Nikola; Montag, Christiane; Gallinat, Jürgen; Lee, Ray X; Stephens, Greg J; Kuhn, Bernd; Tauffer, Luiz; Isope, Philippe; Inoue, Katsuma; Ohmura, Yoshiyuki; Yonekura, Shogo; Kuniyoshi, Yasuo; Jang, Hyun J; Kwag, Jeehyun; de Kamps, Marc; Lai, Yi M; dos Santos, Filipa; Lam, K. P; Andras, Peter; Imperatore, Julia; Helms, Jessica; Tompa, Tamas; Lavin, Antonieta; Inkpen, Felicity H; Ashby, Michael C; Lepora, Nathan F; Shifman, Aaron R; Lewis, John E; Zhang, Zhong; Feng, Yeqian; Tetzlaff, Christian; Kulvicius, Tomas; Li, Yinyun; Pena, Rodrigo F O; Bernardi, Davide; Roque, Antonio C; Lindner, Benjamin; Bernardi, Davide; Vellmer, Sebastian; Saudargiene, Ausra; Maninen, Tiina; Havela, Riikka; Linne, Marja-Leena; Powanwe, Arthur; Longtin, Andre; Naveros, Francisco; Garrido, Jesús A; Graham, Joe W; Dura-Bernal, Salvador; Angulo, Sergio L; Neymotin, Samuel A; Antic, Srdjan D (Journal article / Tidsskriftartikkel / PublishedVersion, 2017)
  • 3-Methylcholanthrene Induces Chylous Ascites in TCDD-Inducible Poly-ADP-Ribose Polymerase (Tiparp) Knockout Mice 
    Cho, Tiffany; Bott, Debbie; Ahmed, Shaimaa; Hutin, David; Gomez, Alvin; Tamblyn, Laura; Zhou, Angela C.; Watts, Tania H.; Grant, Denis M; Matthews, Jason (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    TCDD-inducible poly-ADP-ribose polymerase (TIPARP) is an aryl hydrocarbon receptor (AHR) target gene that functions as part of a negative feedback loop to repress AHR activity. Tiparp−/− mice exhibit increased sensitivity ...
  • 3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry 
    Lin, Ann; Skottvoll, Frøydis Sved; Rayner, Simon; Pedersen-Bjergaard, Stig; Sullivan, Gareth; Krauss, Stefan; Wilson, Steven Ray Haakon; Harrison, Sean (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    In vitro derived simplified 3D representations of human organs or organ functionalities are predicted to play a major role in disease modeling, drug development, and personalized medicine, as they complement traditional ...
  • 3PO inhibits inflammatory NFκB and stress-activated kinase signaling in primary human endothelial cells independently of its target PFKFB3 
    Wik, Jonas Aakre; Lundbäck, Peter; La Cour Poulsen, Lars; Haraldsen, Guttorm; Skålhegg, Bjørn Steen; Hol, Johanna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Inhibition of the key glycolytic activator 6-phosphofructokinase 2/fructose-2,6-bisphosphatase-3 (PFKFB3) by 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one (3PO) strongly attenuates pathological angiogenesis in cancer and ...
  • 4D nucleomes in single cells: what can computational modeling reveal about spatial chromatin conformation? 
    Sekelja, Monika; Paulsen, Jonas; Collas, Philippe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Genome-wide sequencing technologies enable investigations of the structural properties of the genome in various spatial dimensions. Here, we review computational techniques developed to model the three-dimensional genome ...
  • 5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication 
    Prikrylova, Terezia; Robertson, Julia; Ferrucci, Francesca; Konorska, Dorota Joanna; Aanes, Håvard; Manaf, Adeel; Zhang, Beibei; Vågbø, Cathrine Broberg; Kusnierczyk, Anna; Gilljam, Karin Margaretha; Løvkvam-Køster, Caroline; Otterlei, Marit; Dahl, John Arne; Enserink, Jorrit; Klungland, Arne; Robertson, Adam Brian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    In most mammalian cells, DNA replication occurs once, and only once between cell divisions. Replication initiation is a highly regulated process with redundant mechanisms that prevent errant initiation events. In lower ...
  • A Bayesian mixed modeling approach for estimating heritability 
    Nustad, Haakon E; Page, Christian M; Reiner, Andrew H; Zucknick, Manuela; LeBlanc, Marissa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background A Bayesian mixed model approach using integrated nested Laplace approximations (INLA) allows us to construct flexible models that can account for pedigree structure. Using these models, we estimate ...
  • A case of post-transfusion purpura with severe refractory thrombocytopenia but no cutaneous manifestations 
    Bhamra, Jagjit; Iversen, Per Ole; Titze, Thomas K; Tjønnfjord, Geir Erland; Akkøk, Cigdem Ahaein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Posttransfusion purpura is a serious adverse effect of transfusion due to HPA-antibodies. A young female was diagnosed with acute leukaemia, and treatment commenced. Severe thrombocytopenia ensued. No platelet increment ...
  • A cluster-randomized educational intervention to reduce inappropriate prescription patterns for elderly patients in general practice - The Prescription Peer Academic Detailing (Rx-PAD) study [NCT00281450] 
    Straand, Jørund; Fetveit, Arne; Rognstad, Sture; Gjelstad, Svein; Brekke, Mette; Dalen, Ingvild (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background Age-related alterations in metabolism and excretion of medications increase the risk of adverse drug events in the elderly. Inappropriate polypharmacy and prescription practice entails increased ...
  • A comparison of general and ambulance specific stressors: predictors of job satisfaction and health problems in a nationwide one-year follow-up study of Norwegian ambulance personnel 
    Sterud, Tom; Hem, Erlend; Lau, Bjørn; Ekeberg, Øivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Objectives To address the relative importance of general job-related stressors, ambulance specific stressors and individual characteristics in relation to job satisfaction and health complaints (emotional ...
  • A comprehensive metabolic profiling of the metabolically healthy obesity phenotype 
    Telle-Hansen, Vibeke H; Christensen, Jacob J; Formo, Gulla A; Holven, Kirsten B; Ulven, Stine M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as “metabolically healthy obese” (MHO). In contrast to ...
  • A comprehensive multicomponent school-based educational intervention did not affect fruit and vegetable intake at the 14-year follow-up 
    Øvrebø, Bente; Stea, Tonje Holte; te Velde, Saskia J.; Bjelland, Mona; Klepp, Knut Inge; Bere, Elling Tufte (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The intake of fruit and vegetables is associated with beneficial health outcomes, and studies aimed at increasing fruit and vegetable intake lack long-term follow-up. The primary objective of this study was to evaluate the ...
  • A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation 
    Cui, Yixian; Parashar, Smriti; Zahoor, Muhammad; Needham, Patrick; Mari, Muriel; Zhu, Ming; Chen, Shulian; Ho, Hsuan-Chung; Reggiori, F; Farhan, Hesso; Brodsky, Jeffrey L; Ferro-Novick, Susan (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The COPII-cargo adaptor complex Lst1-Sec23 selectively sorts proteins into vesicles that bud from the endoplasmic reticulum (ER) and traffic to the Golgi. Improperly folded proteins are prevented from exiting the ER and ...
  • A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework 
    LeBlanc, Marissa; Zuber, Verena; Thompson, Wesley K; Andreassen, Ole A; Frigessi, Arnoldo; Andreassen, Bettina K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background There is considerable evidence that many complex traits have a partially shared genetic basis, termed pleiotropy. It is therefore useful to consider integrating genome-wide association study ...
  • A cross-sectional prospective study of seclusion, restraint and involuntary medication in acute psychiatric wards: patient, staff and ward characteristics 
    Husum, Tonje L; Bjørngaard, Johan H; Finset, Arnstein; Ruud, Torleif (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Previous research on mental health care has shown considerable differences in use of seclusion, restraint and involuntary medication among different wards and geographical areas. This study ...
  • A day-by-day investigation of changes in criminal convictions before and after entering and leaving opioid maintenance treatment: a national cohort study 
    Bukten, Anne; Røislien, Jo; Skurtveit, Svetlana; Waal, Helge; Gossop, Michael; Clausen, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
  • A diet change from dry food to beef induces reversible changes on the faecal microbiota in healthy, adult client-owned dogs 
    Herstad, Kristin M V; Gajardo, Karina; Bakke, Anne M; Moe, Lars; Ludvigsen, Jane; Rudi, Knut; Rud, Ida; Sekelja, Monika; Skancke, Ellen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Diet has a major influence on the composition of the gut microbiota, whose importance for gut health and overall well-being is increasingly recognized. Knowledge is limited regarding health ...
  • A few more minutes make a difference? The relationship between content and length of GP consultations 
    Gude, Tore; Vaglum, Per Jørgen Wiggen; Anvik, Tor; Baerheim, Anders; Grimstad, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Objectives. To investigate the relationship between the length of a medical consultation in a general practice setting and the biopsychosocial information obtained by the physician, and to explore the characteristics of ...