Search
Now showing items 1-4 of 4
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Myocardial infarction (MI) triggers a reparative response involving fibroblast proliferation and differentiation driving extracellular matrix modulation necessary to form a stabilizing scar. Recently, it was shown that a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency, characterized by inadequate antibody responses and recurrent bacterial infections. Paradoxically, a majority of CVID patients ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background: IL-1β is a highly potent pro-inflammatory cytokine and its secretion is tightly regulated. Inactive pro-IL-1β is transcribed in response to innate immune receptors activating NFκB. If tissue damage occurs, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
The innate immune system is rapidly activated during myocardial infarction and blockade of extracellular complement system reduces infarct size. Intracellular complement, however, appears to be closely linked to metabolic ...