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Now showing items 101-200 of 674
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Ciliopathies are clinically and genetically heterogeneous diseases. We studied three patients from two independent families presenting with features of Joubert syndrome: abnormal breathing pattern during infancy, developmental ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
The majority of people with dementia have behavioral and psychological symptoms of dementia (BPSD), including depression, anxiety and agitation. These may be elicited or aggravated by disrupted ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Current nutritional management of infants born very preterm results in significant deficiency of the essential fatty acids (FAs) arachidonic acid (ARA) and docosahexaenoic acid (DHA). The impact ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Children and adolescents with a lower socioeconomic position have poorer dietary behaviours compared to their counterparts with a higher socioeconomic position. A better understanding of the mechanisms behind such socioeconomic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
To limit SARS-CoV-2 spread, quarantine and isolation are obligatory in several situations in Norway. We found low self-reported adherence to requested measures among 1,704 individuals (42%; 95% confidence interval: 37–48). ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Literature focusing on the association between sedentary behaviours and physical activity has provided equivocal results and has been dominated by TV viewing as the indicator of sedentary behaviour. There is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
BAKGRUNN
Covid-19-pneumoni kan gi alvorlig hypoksemisk respirasjonssvikt som krever intensivmedisinsk behandling. Vi ønsket å beskrive covid-19-intensivpasienter som ble behandlet med og uten invasiv ventilasjonsstøtt ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Cell replacement therapies hold great therapeutic potential. Nevertheless, our knowledge of the mechanisms governing the developmental processes is limited, impeding the quality of differentiation protocols. Generating ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Current studies addressing the influence of interleukin-33 or its receptor (IL-33R/ST2) on development of atopic dermatitis-like inflammation in mice have reported conflicting results. We compared the response in single- ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
The National Early Warning Score (NEWS2) is currently recommended in the UK for the risk stratification of COVID-19 patients, but little is known about its ability to detect severe cases. We aimed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
In breast cancer, immunohistochemistry (IHC) subtypes, together with grade and stage, are well-known independent predictors of breast cancer death. Given the immense changes in breast cancer ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background: Disrupted sleep is common among nursing home patients with dementia and is associated with increased agitation, depression, and cognitive impairment. Detecting and treating sleep problems in this population are ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Generating insulin-producing β-cells from human induced pluripotent stem cells is a promising cell replacement therapy for improving or curing insulin-dependent diabetes. The transplantation of end-stages differentiating ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Large‐scale in vitro drug sensitivity screens are an important tool in personalized oncology to predict the effectiveness of potential cancer drugs. The prediction of the sensitivity of cancer cell lines to a panel of drugs ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
CRISPR/Cas9 is a powerful gene‐editing tool allowing for specific gene manipulation at targeted sites in the genome. Here, we used CRISPR/Cas9‐mediated gene editing to introduce single amino acid mutations into proteins ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background: Extracellular matrix (ECM) remodeling is essential for skeletal muscle development and adaption in response to environmental cues such as exercise and injury. The cell surface proteoglycan syndecan-4 has been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract BACKGROUND: Iodine is crucial for normal growth and neurodevelopment. Before 1950, goitre caused by iodine deficiency was widespread in Norway, but decreased significantly after mandatory fortification of animal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Objective:
Limiting SFA intake may minimise the risk of CHD. However, such reduction often leads to increased intake of carbohydrates. We aimed to evaluate associations and the interplay of carbohydrate and SFA intake ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Grapes contain high concentrations of secondary metabolites and antioxidants that have been linked to a reduction of several chronic diseases. Here, we report results of a UK retail survey, which investigated the effect ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Despite a remarkable decline in global child mortality, more than 6 million children died in 2018, of which 0.9 million (15%) deaths occurred among children aged 5 to 14 years, mostly in low- and middle-income countries ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Recently, a large group of patients with persistent dyspnea, poor physical capacity, and reduced health-related quality of life (HRQoL) following pulmonary embolism (PE) has been identified and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Norwegian children are more frequently hospitalized with influenza than adults. Little is known about the characteristics of these children. Our aim was to investigate the presence of pre-existing risk conditions ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background and Aims: Morphological changes in mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) are well-characterized. Yet, it remains elusive whether these are a consequence of seizures or originate from ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
In the dairy breeding industry, prediction of bull fertility in artificial insemination (AI) is important for efficient and economically sustainable production. However, it is challenging to identify bulls with superior ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Pattern recognition receptors (PRRs) are crucial for responses to infections and tissue damage; however, their role in autoimmunity is less clear. Herein we demonstrate that 2 C-type lectin receptors (CLRs) Mcl and Mincle ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Nicotinamide adenine dinucleotide (NAD+) plays a fundamental role in life and health through the regulation of energy biogenesis, redox homeostasis, cell metabolism, and the arbitration of cell survival via linkages to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
STUDY QUESTION
Have mean age at menarche or mean age at natural menopause changed from the 1939 birth cohort to the 1964 birth cohort?
SUMMARY ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Hippocampal sharp wave ripples (SPW-R) have been identified as key bio-markers of important brain functions such as memory consolidation and decision making. Understanding their underlying mechanisms in healthy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Objective How and to what extent electrical brain activity is affected in pharmacologically altered states of consciousness, where it is mainly the phenomenological content rather than the level of consciousness that is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
We test whether a measure based on the directed transfer function (DTF) calculated from short segments of electroencephalography (EEG) time-series can be used to monitor the state of the patients also ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Dreams are internally generated experiences that occur independently of current sensory input. Here we argue, based on cortical anatomy and function, that dream experiences are tightly related to the workings of a specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Existing evidence on the association between food insecurity and childhood obesity is mixed. In addition, literature from developing countries in general and Ethiopia in particular on the nexus ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Early‐adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It is unclear whether subsequent changes in weight affect risk. We pooled individual‐level data from 17 prospective studies ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Replacing intake of SFA with PUFA reduces serum cholesterol levels and CVD risk. The effect on glycaemic regulation is, however, less clear. The main objective of the present study was to investigate the short-term effect ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Acute bronchiolitis during infancy and human rhinovirus (HRV) lower respiratory tract infections increases the risk of asthma in atopic children. We aimed to explore whether specific viruses, allergic sensitisation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
While high-throughput drug screening offers possibilities to profile phenotypic responses of hundreds of compounds, elucidation of the cell context-specific mechanisms of drug action requires additional analyses. To that ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The rising incidence of cutaneous melanoma over the past few decades has prompted substantial efforts to develop risk prediction models identifying people at high risk of developing melanoma to facilitate targeted screening ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Neisseria gonorrhoeae multilocus sequence type (ST)-7827 emerged in a dramatic fashion in Norway in the period 2016–2018. Here, we aim to shed light on the provenance and expansion of this ST. ST-7827 was found to be ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background
Statins may restrict the cellular functions required for melanoma growth and metastasis.
Objectives
To determine whether long‐term statin use commenced before diagnosis of a primary melanoma is associated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Generalized linear models are often misspecified because of overdispersion, heteroscedasticity and ignored nuisance variables. Existing quasi‐likelihood methods for testing in misspecified models often do not provide ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Concerns have been raised about the use of opioid maintenance treatment (OMT) during pregnancy and negative effects for the offspring. While neonatal outcomes and short-term effects are relatively well ...
Use of immunomodulating drugs and risk of cutaneous melanoma: A nationwide nested case-control study
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Purpose: Cutaneous melanoma is among the fastest growing malignancies in Norway and ultraviolet radiation (UVR) exposure is the primary environmental risk factor. Immunomodulating drugs can increase skin photosensitivity ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
We assessed the effect of weight-loss induced with a low-carbohydrate-high-fat diet with and without exercise, on body-composition, cardiorespiratory fitness and cardiovascular risk factors. A total of 57 overweight and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
The glymphatic system, that is aquaporin 4 (AQP4) facilitated exchange of CSF with interstitial fluid (ISF), may provide a clearance pathway for protein species such as amyloid-β and tau, which accumulate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Recurrent attacks of acute intermittent porphyria (AIP) result in poor quality of life and significant risks of morbidity and mortality. Liver transplantation (LT) offers a cure, but published data on outcomes after LT are ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
3′, 5′ – Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that is involved in many cellular functions and biological processes. In several cell types, cholera toxin will increase the level of cAMP, ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Slow stroking touch activates C-tactile (CT) fibres in the human skin and is typically described as pleasant. Over a longer duration of stroking, affective habituation sets in, indicated by a reduction in rated pleasantness. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Astrocytic Ca2+ signaling has been intensively studied in health and disease but has not been quantified during natural sleep. Here, we employ an activity-based algorithm to assess astrocytic Ca2+ signals in the neocortex ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The calcium-binding proteins parvalbumin and calbindin are expressed in neuronal populations regulating brain networks involved in spatial navigation, memory processes, and social interactions. Information about the numbers ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Microfluidic technology is a valuable tool for realizing more in vitro models capturing cellular and organ level responses for rapid and animal‐free risk assessment of new chemicals and drugs. Microfluidic cell‐based devices ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Objective:
The aim of the current study was to evaluate the effect on frequency, variety and amount of vegetables served and staff’s food-related practices in the multicomponent BRA intervention.
Design:
Cluster ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Aims: This article reports on the development and reliability of two questionnaires that measure adherence to the Norwegian National Guideline on Food and Meals in School among primary schools and after-school services. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Factor VII activating protease (FSAP) is a circulating serine protease of broad specificity that is likely to be involved in many pathophysiological processes. The activation of the circulating zymogen form of FSAP by ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background: Altitude training stresses several physiological and metabolic processes and alters the dietary needs of the athletes. International Olympic Committee (IOC)'s Nutrition Expert Group suggests that athletes should ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background
Adults with intellectual disabilities living in residential houses have a high prevalence of obesity which is related to poor dietary habits.
Aim
The aim of this study was to assess supporting staff`s ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Objectives Oxidised cholesterol metabolites are linked to increased production of the active vitamin A (Vit-A) form and monocyte/macrophage activation, which may be reflected by neopterin, a marker of both interferon-γ–mediated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background and aims Diet may alter gene expression in immune cells involved in atherosclerotic cardiovascular disease susceptibility. However, we still lack a robust understanding of the association between diet and immune ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
In the Wada test, one hemisphere is selectively anaesthetised by unilateral intracarotid injection of a fast-acting anaesthetic agent. This gives a unique opportunity to observe the functions and physiological ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Relatively little is known about the ecological forces shaping the gut microbiota composition during infancy. Therefore, the objective of the present study was to identify the nutrient utilization- and short-chain fatty ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Genetic and clinical observations have indicated T cells are involved in MS pathology. There is little insight in how T cells are involved and whether or not these can be used as markers for MS. Objectives ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Despite the fact that the estrogenic effects of bisphenols were first described 80 years ago, recent data about its potential negative impact on birth outcome parameters raises a strong rationale to investigate further. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract The time after a breast cancer diagnosis is a potential period for making positive dietary changes, but previous results are conflicting. The main aim of the present study was to study breast cancer patients’ ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The prevalence of dry eye disease is high worldwide and poses a great burden on patients’ daily lives. Accurate diagnosis of the disease is important, and it requires application of various methods. Hyperosmolarity is ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
We introduce a new concept called “Iterative Multi-Mode Discretization (IMMD)” which is a new type of efficient data sparsification that can scale up many tasks in data mining. In this paper we demonstrate the application ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
We aimed to investigate the association between baseline levels of total serum glutathione (tGSH) and rate of chronic disease accumulation over time. The study population (n = 2,596) was derived from a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
The objective was to investigate which predictive equations provide the best estimates of resting energy expenditure (REE) in postpartum women with overweight and obesity. Lactating women with overweight or ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background: Over the past two decades, hybrid and total minimally invasive esophagectomy for esophageal cancer (EC) has increasingly been implemented with the aim to improve morbidity, functional result and ultimately the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Mathematical modeling and simulation is a promising approach to personalizedcancer medicine. Yet, the complexity, heterogeneity and multi-scale nature ofcancer pose significant computational challenges. Coupling discrete ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Objective. To determine longitudinal changes in lifestyle behaviour and lipid management in a chronic coronary heart disease (CHD) population. Design. A multi-centre cohort study consecutively included 1127 patients at ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background and aims
A first-time acute myocardial infarction (AMI) is a severe diagnosis that leads to initiation or intensification of lipid-lowering medication to prevent recurrent events. Individuals with familial ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Introduction
We aimed to investigate QoL in EA patients in relation to comparison groups and to clinical factors including experienced traumatic stress.
Material and Methods
Adolescents with EA in Norway born between ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Chronic brain pathology and pre-stroke cognitive impairment (PCI) is predictive of post-stroke dementia. The aim of the current study was to measure pre-stroke neurodegenerative and vascular ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
Fish consumption is associated with reduced risk of CVD, which may be partly mediated by alterations in plasma lipids, such as HDL-cholesterol. However, comprehensive analyses of associations between fatty ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
Purpose of Review
Human pancreas-on-a-chip (PoC) technology is quickly advancing as a platform for complex in vitro modeling of islet physiology. This review summarizes the current progress ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
BACKGROUND:
An electroencephalogram (EEG) is the most dominant method for detecting epileptic seizures. However, the existing techniques use single-channel EEGs from public databases and the sample size is small.
OBJ ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Aim
Adult neurogenesis occurs in two major niches in the brain: the subgranular zone of the hippocampal formation and the ventricular‐subventricular zone. Neurogenesis in both niches is reduced in ageing and neurological ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Study design
A national, retrospective, cross-sectional study.
Objectives
To analyze the prevalence of pressure injury (PI), and characteristics associated with PI development in the hospitalized population of persons ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Inhibition of the key glycolytic activator 6-phosphofructokinase 2/fructose-2,6-bisphosphatase-3 (PFKFB3) by 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one (3PO) strongly attenuates pathological angiogenesis in cancer and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Enterococcus faecium is a gut commensal of the gastro-digestive tract, but also known as nosocomial pathogen among hospitalized patients. Population genetics based on whole-genome sequencing has revealed that E. faecium ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background & aims
The Scored Patient-Generated Subjective Global Assessment (PG-SGA©) is a validated nutritional screening, assessment, monitoring, and triage tool. When translated to other languages, the questions and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background and aims
Gastrointestinal (GI) symptoms, malabsorption, reduced food intake and weight loss are common sequela of gastrectomy. This can result in malnutrition with a subsequent prolonged recovery, reduced ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Scope
It is aimed to investigate how intake of high‐fat meals composed of different dairy products with a similar fat content affects postprandial peripheral blood mononuclear cell (PBMC) expression of inflammation‐related ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Brainstem regions support vital bodily functions, yet their genetic architectures and involvement in common brain disorders remain understudied. Here, using imaging-genetics data from a discovery sample of 27,034 individuals, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Essential for successful interaction with the environment is the human capacity to resolve events in time. Typical event timing paradigms are judgements of simultaneity (SJ) and of temporal order (TOJ). It remains unclear ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
We describe a novel, easy and efficient combinatorial phage display peptide substrate‐mining method to map the substrate specificity of proteases. The peptide library is displayed on the pVII capsid of the M13 bacteriophage, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
To maintain homeostasis, all cells respond to environmental cues via a multitude of surface receptors. In order to act appropriately in their environment, cells are dependent on the transduction of the incoming signal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Aims
Blockade of β-adrenoceptors reduces sympathetic nervous system activity and improves survival in patients with heart failure with reduced left ventricular ejection fraction ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background and aims: The comparative effectiveness of sigmoidoscopy and fecal immunochemical testing (FIT) for colorectal cancer (CRC) screening is unknown. Methods: Individuals aged 50-74 years living in South-East Norway ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Being able to replicate real experiments with computational simulations is a unique opportunity to refine and validate models with experimental data and redesign the experiments based on simulations. However, since it is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The volume, composition, and movement of the cerebrospinal fluid (CSF) are important for brain physiology, pathology, and diagnostics. Nevertheless, few studies have focused on the main structure that produces CSF, the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Several theories link consciousness to complex cortical dynamics, as suggested by comparison of brain signal diversity between conscious states and states where consciousness is lost or reduced. In particular, Lempel-Ziv ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Background
Accumulating evidence links paternal adiposity in the periconceptional period to offspring health outcomes. DNA methylation has been proposed as a mediating mechanism, ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background
Major cancers are associated with lifestyle, and previous studies have found that the non-immigrant populations in the Nordic countries have higher incidence rates of most cancers than the immigrant populations. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Aim
To analyse the use of radiotherapy (RT) and factors affecting overall survival (OS) after RT in breast cancer patients with brain metastases.
Methods
Breast cancer patients treated from 2008 to 2018 with whole ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Autophagosome biogenesis involves de novo formation of a membrane that elongates to sequester cytoplasmic cargo and closes to form a double-membrane vesicle (an autophagosome). This process has remained enigmatic since its ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Previous unimodal PET and fMRI studies in humans revealed a reproducible vestibular brain activation pattern, but with variations in its weighting and expansiveness. Hybrid studies minimizing methodological variations at ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Objective To investigate any changes in mental distress levels over 20 years among medical students, as well as the clinical importance of these changes. Design Two cross-sectional surveys 20 years apart. Setting The ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The aim was to compile the evidence from Randomized Controlled Trials (RCTs) of diet or dietary supplements used to reduce disease activity in adults with Rheumatoid Arthritis (RA). Searches were performed in the databases ...