Browsing Institutt for medisinske basalfag by Title

Now showing items 425-444 of 3153

  • C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation 
    N'Diaye, Marie; Brauner, Susanna; Flytzani, Sevasti; Kular, Lara; Warnecke, Andreas; Adzemovic, Milena Z.; Piket, Eliane; Min, Jin-Hong; Edwards, Will; Mela, Filia; Choi, Hoi Ying; Magg, Vera; James, Tojo; Lindén, Magdalena; Reichardt, Holger M.; Daws, Michael Rory; Van Horssen, Jack; Kockum, Ingrid; Harris, Robert A.; Olsson, Tomas; Guerreiro-Cacais, Andre O.; Jagodic, Maja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Pattern recognition receptors (PRRs) are crucial for responses to infections and tissue damage; however, their role in autoimmunity is less clear. Herein we demonstrate that 2 C-type lectin receptors (CLRs) Mcl and Mincle ...
  • CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing 
    Lehr, Andrew; Kumar, Arvind; Tezlaff, Christian; Hafting, Torkel; Fyhn, Marianne; Stöber, Tristan Manfred (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Hippocampal region CA2 has received increased attention due to its importance in social recognition memory. While its specific function remains to be identified, there are indications that CA2 plays a major role in a variety ...
  • Ca2+ signals in astrocytes facilitate spread of epileptiform activity 
    Heuser, Kjell; Nome, Cecilie; Pettersen, Klas; Åbjørsbråten, Knut Sindre; Jensen, Vidar; Tang, Wannan; Sprengel, Rolf; Taubøll, Erik; Nagelhus, Erlend Arnulf; Enger, Rune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Epileptic seizures are associated with increased astrocytic Ca2+ signaling, but the fine spatiotemporal kinetics of the ictal astrocyte–neuron interplay remains elusive. By using 2-photon imaging of awake head-fixed mice ...
  • Ca2+-mediated activation of ERK in hepatocytes by norepinephrine and prostaglandin F2α: role of calmodulin and src kinases 
    Melien, Øyvind; Nilssen, Laila S; Dajani, Olav F; Larsen Sand, Kristin; Iversen, Jens-Gustav; Sandnes, Dagny L; Christoffersen, Thoralf (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2002)
    Background Previous studies have shown that several agents that stimulate heptahelical G-protein coupled receptors activate the extracellular signal regulated kinases ERK1 (p44mapk) and ERK2 (p42mapk) in ...
  • Calcium from salmon and cod bone is well absorbed in young healthy men: a double-blinded randomised crossover design 
    Malde, Marian K; Bügel, Susanne; Kristensen, Mette; Malde, Ketil; Graff, Ingvild E; Pedersen, Jan I (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Calcium (Ca) - fortified foods are likely to play an important role in helping the consumer achieve an adequate Ca intake, especially for persons with a low intake of dairy products. Fish bones ...
  • Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas. 
    Eich, Torsten M.; Ståhle, Magnus; Gustafsson, Bengt; Horneland, Rune; Lempinen, Marko; Lundgren, Torbjörn; Rafael, Ehab; Tufveson, Gunnar; Zur-Mühlen, Bengt; Olerud, Johan; Scholz, Hanne; Korsgren, Olle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: Effective digestive enzymes are crucial for successful islet isolation. Supplemental proteases are essential because they synergize with collagenase for effective pancreatic digestion. The activity of these ...
  • Calculating unreported confidence intervals for paired data 
    Hirji, Karim F; Fagerland, Morten W (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Confidence intervals (or associated standard errors) facilitate assessment of the practical importance of the findings of a health study, and their incorporation into a meta-analysis. For paired ...
  • Calibrating regionally downscaled precipitation over Norway through quantile-based approaches 
    Bolin, David; Frigessi, Arnoldo; Guttorp, Peter; Haug, Ola; Orskaug, Elisabeth; Scheel, Ida; Wallin, Jonas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Dynamical downscaling of earth system models is intended to produce high-resolution climate information at regional to local scales. Current models, while adequate for describing temperature distributions at relatively ...
  • Calibration of the comet assay using ionising radiation 
    Brunborg, Gunnar; Eide, Dag Markus; Graupner, Anne; Gutzkow, Kristine Bjerve; Shaposhnikov, Sergey; Kruszewski, Marcin; Sirota, Nikolay; Jones, George D. D.; Koppen, Gudrun; Vanhavere, Filip; Møller, Peter; Stetina, Rudolf; Dahl, Hildegunn; Collins, Andrew Richard Sherman (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Several trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks ...
  • Calming Effects of Touch in Human, Animal, and Robotic Interaction — Scientific State-of-the-Art and Technical Advances 
    Eckstein, Monika; Mamaev, Ilshat; Ditzen, Beate; Sailer, Uta (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Small everyday gestures such as a tap on the shoulder can affect the way humans feel and act. Touch can have a calming effect and alter the way stress is handled, thereby promoting mental and physical health. Due to current ...
  • cAMP Signalling in Modification of DNA Damage Responses in Lymphoid Cells : Implications for Development and Treatment of BCP-ALL 
    Naderi, Elin Hallan (Doctoral thesis / Doktoravhandling, 2010)
    DNA damage responses are important both in the development and treatment of cancers. The main focus of the present thesis has been to explore whether the level of the second messenger cAMP can affect the cell’s response ...
  • cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53 
    Skah, Seham; Richartz, Nina; Duthil, Eva; Gilljam, Karin Margaretha; Bindesbøll, Christian; Naderi, Elin Hallan; Eriksen, Agnete Bratsberg; Ruud, Ellen; Dirdal, Marta Maria; Simonsen, Anne; Blomhoff, Heidi Kiil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Autophagy is important in regulating the balance between cell death and survival, with the tumor suppressor p53 as one of the key components in this interplay. We have previously utilized an in vitro model of the most ...
  • cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53 
    Skah, Seham; Richartz, Nina; Duthil, Eva; Gilljam, Karin Margaretha; Bindesbøll, Christian; Naderi, Elin Hallan; Eriksen, Agnete Bratsberg; Ruud, Ellen; Dirdal, Marta Maria; Simonsen, Anne; Blomhoff, Heidi Kiil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Autophagy is important in regulating the balance between cell death and survival, with the tumor suppressor p53 as one of the key components in this interplay. We have previously utilized an in vitro model of the most ...
  • Can antibiotic prescriptions in respiratory tract infections be improved? A cluster-randomized educational intervention in general practice - The Prescription Peer Academic Detailing (Rx-PAD) Study [NCT00272155] 
    Gjelstad, Svein; Fetveit, Arne; Straand, Jørund; Dalen, Ingvild; Rognstad, Sture; Lindbaek, Morten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background More than half of all antibiotic prescriptions in general practice are issued for respiratory tract infections (RTIs), despite convincing evidence that many of these infections are caused by ...
  • Can breast cancer be stopped? Modifiable risk factors of breast cancer among women with a prior benign or premalignant lesion 
    Lilleborge, Marie; Falk, Ragnhild Sørum; Sørlie, Therese; Ursin, Giske; Hofvind, Solveig (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Physical inactivity, high postmenopausal body mass index, alcohol consumption and use of menopausal hormone therapy are established risk factors for breast cancer. Less is known about whether these factors influence the ...
  • Can interruption of innate immune recognition-mediated emergency myelopoiesis impede tumor progression? 
    Malliack, Rahul; Duttaroy, Asim Kanti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Cancer cells survive and grow despite various advanced anti-cancer therapy. To overcome this antineoplastic resistance, adjuvant therapy is often required to prevent cancer cells' immunoescape capacity. Established tumors ...
  • Can plant-derived anti-HIV compounds be used in COVID-19 cases? 
    Das, Diptimayee; Bihari Jena, Atala; Banerjee, Antara; Kumar Radhakrishnan, Arun; Duttaroy, Asim Kanti; Pathak, Surajit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    People living with HIV are more exposed to the adverse health effects of the worldwide COVID-19 pandemic. The pandemic's health and social repercussions may promote drug abuse and inadequate HIV management among this ...
  • Can we rely on simulated patients’ satisfaction with their consultation for assessing medical students’ communication skills? A cross-sectional study 
    Gude, T.; Grimstad, H.; Holen, A.; Anvik, T.; Baerheim, A.; Fasmer, O. B; Hjortdahl, P; Vaglum, P. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background In medical education, teaching methods offering intensive practice without high utilization of faculty resources are needed. We investigated whether simulated patients’ (SPs’) satisfaction with ...
  • Cancer epidemiology in practice: Working notes on cancer history-based selection and censoring 
    Berge, Leon Alexander Mclaren; Grimsrud, Tom Kristian; Babigumira, Ronnie; Støer, Nathalie Charlotte; Shala, Nita Kaupang; Veierød, Marit Bragelien; Stenehjem, Jo Steinson (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Researchers conducting observational studies of exposure-cancer associations must make decisions regarding the selection and censoring of study subjects with respect to their cancer history. Given available information, ...
  • Cancer incidence and mortality among firefighters 
    Jalilian, Hamed; Ziaei, Mansour; Weiderpass, Elisabete; Rueegg, Corina Silvia; Khosravi, Yahya; Kjærheim, Kristina (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Firefighters are exposed to both known and suspected carcinogens. This study aims to systematically review the literature on the association of firefighting occupation and cancer incidence and mortality, overall and for ...